Package: cobenrich 1.0.1

Jiangtao Gou

cobenrich: Using Multiple Continuous Biomarkers for Patient Enrichment in Two-Stage Clinical Designs

Enrichment strategies play a critical role in modern clinical trial design, especially as precision medicine advances the focus on patient-specific efficacy. Recent developments in enrichment design have introduced biomarker randomness and accounted for the correlation structure between treatment effect and biomarker, resulting in a two-stage threshold enrichment design. We propose novel two-stage enrichment designs capable of handling two or more continuous biomarkers. See Zhang, F. and Gou, J. (2025). Using multiple biomarkers for patient enrichment in two-stage clinical designs. Technical Report.

Authors:Jiangtao Gou [aut, cre], Fengqing Zhang [aut]

cobenrich_1.0.1.tar.gz
cobenrich_1.0.1.tar.gz(r-4.7-any)cobenrich_1.0.1.tar.gz(r-4.6-any)
cobenrich_1.0.1.tgz(r-4.6-emscripten)
manual.pdf |manual.html
card.svg |card.png
cobenrich/json (API)

# Install 'cobenrich' in R:
install.packages('cobenrich', repos = c('https://cran.r-universe.dev', 'https://cloud.r-project.org'))

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This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

1.00 score 139 downloads 5 exports 7 dependencies

Last updated from:3f8155d2e6. Checks:4 OK. Indexed: yes.

TargetResultTimeFilesSyslog
linux-devel-x86_64OK97
source / vignettesOK192
linux-release-x86_64OK101
wasm-releaseOK96

Exports:avetrteff2findATE2findSATE2targetDeltargetLam

Dependencies:gmmlatticeMatrixmvtnormsandwichtmvtnormzoo