Package: wnl 0.8.1

Kyun-Seop Bae

wnl: Minimization Tool for Pharmacokinetic-Pharmacodynamic Data Analysis

This is a set of minimization tools (maximum likelihood estimation and least square fitting) to solve examples in the Johan Gabrielsson and Dan Weiner's book "Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications" 5th ed. (ISBN:9198299107). Examples include linear and nonlinear compartmental model, turn-over model, single or multiple dosing bolus/infusion/oral models, allometry, toxicokinetics, reversible metabolism, in-vitro/in-vivo extrapolation, enterohepatic circulation, metabolite modeling, Emax model, inhibitory model, tolerance model, oscillating response model, enantiomer interaction model, effect compartment model, drug-drug interaction model, receptor occupancy model, and rebound phenomena model.

Authors:Kyun-Seop Bae [aut]

wnl_0.8.1.tar.gz
wnl_0.8.1.tar.gz(r-4.5-noble)wnl_0.8.1.tar.gz(r-4.4-noble)
wnl_0.8.1.tgz(r-4.4-emscripten)wnl_0.8.1.tgz(r-4.3-emscripten)
wnl.pdf |wnl.html✨
wnl/json (API)
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26 exports 1 stars 0.23 score 1 dependencies 6 scripts 1.2k downloads

Last updated 4 months agofrom:6634ac5b07. Checks:OK: 2. Indexed: yes.

Exports:cmpChiComp1DATdxeEnvObjExpandDHg2invHougaardhSkewnCompnGradientnHessiannlrObjDefObjEstObjLSpComppProfprunrun.tests2oSecondarySolComp2SolComp3wnl5

Dependencies:numDeriv