Package: randomizeR 3.0.2

Ralf-Dieter Hilgers

randomizeR: Randomization for Clinical Trials

This tool enables the user to choose a randomization procedure based on sound scientific criteria. It comprises the generation of randomization sequences as well the assessment of randomization procedures based on carefully selected criteria. Furthermore, 'randomizeR' provides a function for the comparison of randomization procedures.

Authors:David Schindler [aut], Diane Uschner [aut], Denis Razsolkov [ctb], Dimitar Mihaylov [ctb], Marcia Viviane Rueckbeil [ctb], Martin Manolov [ctb], Thi Mui Pham [ctb], Michael Martini [ctb], Ralf-Dieter Hilgers [aut, ths, cre], Nicole Heussen [aut, ths], Daniel Bodden [ctb]

randomizeR_3.0.2.tar.gz
randomizeR_3.0.2.tar.gz(r-4.5-noble)randomizeR_3.0.2.tar.gz(r-4.4-noble)
randomizeR_3.0.2.tgz(r-4.4-emscripten)randomizeR_3.0.2.tgz(r-4.3-emscripten)
randomizeR.pdf |randomizeR.html
randomizeR/json (API)

# Install 'randomizeR' in R:
install.packages('randomizeR', repos = c('https://cran.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

66 exports 2 stars 2.14 score 91 dependencies 8 mentions 42 scripts 562 downloads

Last updated 1 years agofrom:a1a068e84f. Checks:OK: 1 NOTE: 1. Indexed: yes.

TargetResultDate
Doc / VignettesOKSep 13 2024
R-4.5-linuxNOTESep 13 2024

Exports:aabcdParanalyseassessbbcdParblocksbsdParchenParchronBiascoincombineBiascomparecorGuesscreateParamcreateSeqcrParderFuncdoublyF_valuesebcParevaluateexpEndpgbcdPargenNcps_newgenSeqget_p_values_newgetAllSeqgetCorGuessesgetDesFuncgetDesigngetDesScoresgetDistributionParsgetExpectationgetProbgetRandListGSD_allocationGSD_allocation_seqhadaParimbalKmethodmpParmtiNnormEndppbrParplotplotDesplotEvplotSeqprobUnDesrandBlocksrarParratiorhorpbrParrtbdParsaveAssesssaveRandselBiassetPowersummarysurvEndptbdParTVtypeudPar

Dependencies:base64encbigDbitopsbslibcachemclicodetoolscoincolorspacecommonmarkcpp11curldata.tabledigestdplyrevaluatefansifarverfastmapfontawesomefsgenericsggplot2gluegsDesigngtgtablehighrhtmltoolshtmlwidgetsinsightisobandjquerylibjsonlitejuicyjuiceknitrlabelinglatticelibcoinlifecyclemagrittrmarkdownMASSMatrixmatrixStatsmemoisemgcvmimemodeltoolsmstatemultcompmunsellmvtnormnlmepillarpkgconfigplotrixplyrpurrrPwrGSDr2rtfR6rappdirsRColorBrewerRcppreactablereactRreshape2rlangrmarkdownsandwichsassscalesstringistringrsurvivalTH.datatibbletidyrtidyselecttinytexutf8V8vctrsviridisLitewithrxfunxml2xtableyamlzoo

Readme and manuals

Help Manual

Help pageTopics
Randomization for Clinical TrialsrandomizeR-package randomizeR
Function returning the adjusting parameter a slot of an S4 objecta
Representing Accelerated Biased Coin DesignabcdPar
Creates stratified sequences Compares stratified sequences to their respective non-stratified version under the influence of bias.analyse
Assessing randomization sequencesassess assess,randSeq,endpoint-method assess,randSeq,missing-method
Representing Bayesian Biased Coin DesignbbcdPar
Function returning the block slot of an S4 objectblocks
Representing Big Stick DesignbsdPar
Representing Chen's DesignchenPar
Representing chronological biaschronBias
Function returning the coin slot of an S4 objectcoin
Combined bias criterioncombineBias
Comparison of randomization procedurescompare compare,issue,endpoint-method compare,issue,missing-method
Representing the expected number of correct guessescorGuess
Representing any randomization procedurecreateParam
Query to create a randomization sequence of a particular randomization procedurecreateSeq
Representing Complete RandomizationcrPar
Representing Derringer-Suich desirability functionsderFunc
Desirability functions within the scope of clinical trialsdesirability
Representing Efron's Biased Coin DesignebcPar
Evaluation of several randomization procedures with respect to certain desirability functions applied to specified issues.evaluate evaluate,character-method evaluate,missing-method
Representation of exponentially distributed endpointsexpEndp
Representing Generalized Biased Coin DesigngbcdPar
Complete set of randomization sequencesgenerateAllSequences getAllSeq getAllSeq,abcdPar-method getAllSeq,bbcdPar-method getAllSeq,bsdPar-method getAllSeq,chenPar-method getAllSeq,crPar-method getAllSeq,ebcPar-method getAllSeq,gbcdPar-method getAllSeq,hadaPar-method getAllSeq,mpPar-method getAllSeq,pbrPar-method getAllSeq,rarPar-method getAllSeq,tbdPar-method getAllSeq,udPar-method
Generate random sequencesgenerateRandomSequences genSeq genSeq,abcdPar,missing,missing-method genSeq,abcdPar,missing,numeric-method genSeq,abcdPar,numeric,missing-method genSeq,abcdPar,numeric,numeric-method genSeq,bbcdPar,missing,missing-method genSeq,bbcdPar,missing,numeric-method genSeq,bbcdPar,numeric,missing-method genSeq,bbcdPar,numeric,numeric-method genSeq,bsdPar,missing,missing-method genSeq,bsdPar,missing,numeric-method genSeq,bsdPar,numeric,missing-method genSeq,bsdPar,numeric,numeric-method genSeq,chenPar,missing,missing-method genSeq,chenPar,missing,numeric-method genSeq,chenPar,numeric,missing-method genSeq,chenPar,numeric,numeric-method genSeq,crPar,missing,missing-method genSeq,crPar,missing,numeric-method genSeq,crPar,numeric,missing-method genSeq,crPar,numeric,numeric-method genSeq,ebcPar,missing,missing-method genSeq,ebcPar,missing,numeric-method genSeq,ebcPar,numeric,missing-method genSeq,ebcPar,numeric,numeric-method genSeq,gbcdPar,missing,missing-method genSeq,gbcdPar,missing,numeric-method genSeq,gbcdPar,numeric,missing-method genSeq,gbcdPar,numeric,numeric-method genSeq,hadaPar,missing,missing-method genSeq,hadaPar,missing,numeric-method genSeq,hadaPar,numeric,missing-method genSeq,hadaPar,numeric,numeric-method genSeq,mpPar,missing,missing-method genSeq,mpPar,missing,numeric-method genSeq,mpPar,numeric,missing-method genSeq,mpPar,numeric,numeric-method genSeq,pbrPar,missing,missing-method genSeq,pbrPar,missing,numeric-method genSeq,pbrPar,numeric,missing-method genSeq,pbrPar,numeric,numeric-method genSeq,rarPar,missing,missing-method genSeq,rarPar,missing,numeric-method genSeq,rarPar,numeric,missing-method genSeq,rarPar,numeric,numeric-method genSeq,rpbrPar,missing,missing-method genSeq,rpbrPar,missing,numeric-method genSeq,rpbrPar,numeric,missing-method genSeq,rpbrPar,numeric,numeric-method genSeq,rtbdPar,missing,missing-method genSeq,rtbdPar,missing,numeric-method genSeq,rtbdPar,numeric,missing-method genSeq,rtbdPar,numeric,numeric-method genSeq,tbdPar,missing,missing-method genSeq,tbdPar,missing,numeric-method genSeq,tbdPar,numeric,missing-method genSeq,tbdPar,numeric,numeric-method genSeq,udPar,missing,missing-method genSeq,udPar,missing,numeric-method genSeq,udPar,numeric,missing-method genSeq,udPar,numeric,numeric-method
Calculation of the NCPs of each randomization sequence for the doubly noncentral t-distributiongenNcps_new
Calculating p valuesget_p_values_new
Matrix of the guesses of the investigatorgetCorGuesses
Type of Desirability functiongetDesFunc getDesFunc,derringerLs-method getDesFunc,derringerRs-method getDesFunc,derringerTs-method
Design of a randomization proceduregetDesign getDesign,abcdPar-method getDesign,abcdSeq-method getDesign,bbcdPar-method getDesign,bbcdSeq-method getDesign,bsdPar-method getDesign,bsdSeq-method getDesign,chenPar-method getDesign,chenSeq-method getDesign,crPar-method getDesign,crSeq-method getDesign,ebcPar-method getDesign,ebcSeq-method getDesign,gbcdPar-method getDesign,gbcdSeq-method getDesign,hadaPar-method getDesign,hadaSeq-method getDesign,mpPar-method getDesign,mpSeq-method getDesign,pbrPar-method getDesign,pbrSeq-method getDesign,rarPar-method getDesign,rarSeq-method getDesign,rpbrPar-method getDesign,rRpbrSeq-method getDesign,rRtbdSeq-method getDesign,rtbdPar-method getDesign,tbdPar-method getDesign,tbdSeq-method getDesign,udPar-method getDesign,udSeq-method
Applying desirability functions on issues of individual randomization sequencesgetDesScores getDesScores,assessment,missing-method getDesScores,assessment,numeric-method
Get distribution parameters of a randomization listgetDistributionPars getDistributionPars,randSeq,chronBias,survEndp-method getDistributionPars,randSeq,combinedBias,survEndp-method getDistributionPars,randSeq,combinedBiasStepTrend,survEndp-method getDistributionPars,randSeq,missing,survEndp-method getDistributionPars,randSeq,selBias,survEndp-method
Get expectations of a randomization listgetExpectation getExpectation,randSeq,chronBias,expEndp-method getExpectation,randSeq,chronBias,missing-method getExpectation,randSeq,chronBias,normEndp-method getExpectation,randSeq,chronBias,survEndp-method getExpectation,randSeq,combinedBias,expEndp-method getExpectation,randSeq,combinedBias,normEndp-method getExpectation,randSeq,combinedBias,survEndp-method getExpectation,randSeq,combinedBiasStepTrend,expEndp-method getExpectation,randSeq,combinedBiasStepTrend,normEndp-method getExpectation,randSeq,combinedBiasStepTrend,survEndp-method getExpectation,randSeq,missing,expEndp-method getExpectation,randSeq,missing,normEndp-method getExpectation,randSeq,missing,survEndp-method getExpectation,randSeq,power,normEndp-method getExpectation,randSeq,selBias,expEndp-method getExpectation,randSeq,selBias,missing-method getExpectation,randSeq,selBias,normEndp-method getExpectation,randSeq,selBias,survEndp-method
Theoretical probability for randomization sequencescalcProb calculateProbabilities getProb getProb,abcdSeq-method getProb,bbcdSeq-method getProb,bsdSeq-method getProb,chenSeq-method getProb,crSeq-method getProb,ebcSeq-method getProb,gbcdSeq-method getProb,hadaSeq-method getProb,mpSeq-method getProb,pbrSeq-method getProb,rarSeq-method getProb,tbdSeq-method getProb,udSeq-method getProbabilities
Accessor function for the randomization listgetRandList getRandomizationList
Calculates the Type I error for different randomization sequences from a randomization procedure for a group sequential designGSD_allocation
Calculates the Type I error for a randomization sequence in a group sequential designGSD_allocation_seq
Representing Hadamard RandomizationhadaPar
Representing the allocation imbalanceimbal
Assessment criteria for clinical trialsissue issues
Function returning the number of trial arms slot of an S4 objectK
Method returning the rate parameter of an expEndp S4 objectlambda
Function returning the method of an S4 objectmethod
Representing Maximal ProcedurempPar
Function returning the MTI slot of an S4 objectmti
Access the expectation value slot of a normEndp S4 objectmu
Function returning the sample size slot of an S4 objectN
Representation of normally distributed endpointsnormEndp
Overview over the parameters used in the 'randomizeR' packageoverview
Representing Permuted Block RandomizationpbrPar
Generic plotting of comparison objectsplot plot,comparison,character-method plot,comparison,missing-method
desScore plottingplotDes
Evaluation plottingplotEv
Sequence plottingplotSeq
Computing the probability of having desirability scores of zeroprobUnDes probUnDes,desScores-method
Function returning the block slot of an S4 objectrandBlocks
Settings for randomization proceduresrandPar
An S4 Class for the representation of randomization sequencesrandSeq-class
Representing Random Allocation RulerarPar
Function returning the allocation ratio slot of an S4 objectratio
Function returning the adjusting parameter rho slot of an S4 objectrho
Representing Randomized Permuted Block RandomizationrpbrPar
Representing Randomized Truncated Binomial DesignrtbdPar
Saving an assess objectsaveAssess
Saving a randomization listssaveRand
Method returning the scale parameter of an survEndp S4 objectscale
Function returning the allocation seed slot of an objectseed
Representing selection biasselBias
Representing the powersetPower
Method returning the shape parameter of an survEndp S4 objectshape
Function returning the standard deviation slot of a normEndp S4 objectsigma
Summary of assessments of a randomization proceduresummary summary,assessment-method summary,desScores-method
Representation of survival endpointssurvEndp
Representing Truncated Binomal DesigntbdPar
Function returning the target value slot of an S4 objectTV
Get type of an objecttype
Representing Wei's Urn DesignudPar