Package: phase1RMD 1.0.9
Jun Yin
phase1RMD: Repeated Measurement Design for Phase I Clinical Trial
Implements our Bayesian phase I repeated measurement design that accounts for multidimensional toxicity endpoints from multiple treatment cycles. The package also provides a novel design to account for both multidimensional toxicity endpoints and early-stage efficacy endpoints in the phase I design. For both designs, functions are provided to recommend the next dosage selection based on the data collected in the available patient cohorts and to simulate trial characteristics given design parameters. Yin, Jun, et al. (2017) <doi:10.1002/sim.7134>.
Authors:
phase1RMD_1.0.9.tar.gz
phase1RMD_1.0.9.tar.gz(r-4.5-noble)phase1RMD_1.0.9.tar.gz(r-4.4-noble)
phase1RMD_1.0.9.tgz(r-4.4-emscripten)phase1RMD_1.0.9.tgz(r-4.3-emscripten)
phase1RMD.pdf |phase1RMD.html✨
phase1RMD/json (API)
| # Install 'phase1RMD' in R: |
| install.packages('phase1RMD', repos = c('https://cran.r-universe.dev', 'https://cloud.r-project.org')) |
- eff_dat - Patient efficacy data
- patdata - Patient toxicity data
- probaT - The probability matrix of toxicity events
- tox.matrix - Probability matrix for toxicity
- tox_dat - Patient toxicity data
- tox_dat_bytype - Patient toxicity data
This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.
Last updated 5 years agofrom:110b553a2f. Checks:OK: 2. Indexed: no.
| Target | Result | Date |
|---|---|---|
| Doc / Vignettes | OK | Dec 07 2024 |
| R-4.5-linux | OK | Dec 07 2024 |
Exports:GenToxProbparmplot.RunRMDValRunRMDRunRMDEFFSimRMDSimRMDEFFTox2nTTP
Dependencies:arrayhelpersbootclicodacolorspacefansifarverggplot2gluegtableisobandlabelinglatticelifecyclemagrittrMASSMatrixmgcvmunsellmvtnormnlmepillarpkgconfigR6RColorBrewerrjagsrlangscalessvUnittibbleutf8vctrsviridisLitewithr
