{ "_id": "6a2923ae732311cd8759da50", "Package": "phase1RMD", "Version": "1.0.9", "Date": "2020-03-08", "Title": "Repeated Measurement Design for Phase I Clinical Trial", "Author": "Jun Yin, Yu Du, Sumithra Mandrekar", "Maintainer": "Jun Yin ", "Description": "Implements our Bayesian phase I repeated measurement\ndesign that accounts for multidimensional toxicity endpoints\nfrom multiple treatment cycles. The package also provides a\nnovel design to account for both multidimensional toxicity\nendpoints and early-stage efficacy endpoints in the phase I\ndesign. For both designs, functions are provided to recommend\nthe next dosage selection based on the data collected in the\navailable patient cohorts and to simulate trial characteristics\ngiven design parameters. Yin, Jun, et al. 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