Package: metasplines 0.1.1

Tommi Härkänen

metasplines: Pool Literature-Based and Individual Participant Data Based Spline Estimates

Pooling estimates reported in meta-analyses (literature-based, LB) and estimates based on individual participant data (IPD) is not straight-forward as the details of the LB nonlinear function estimate are not usually reported. This package pools the nonlinear IPD dose-response estimates based on a natural cubic spline from lm or glm with the pointwise LB estimates and their estimated variances. Details will be presented in Härkänen, Tapanainen, Sares-Jäske, Männistö, Kaartinen and Paalanen (2026) "Novel pooling method for nonlinear cohort analysis and meta-analysis estimates: Predicting health outcomes based on climate-friendly diets" Epidemiology <doi:10.1097/EDE.0000000000001932>.

Authors:Tommi Härkänen [aut, cre]

metasplines_0.1.1.tar.gz
metasplines_0.1.1.tar.gz(r-4.7-any)metasplines_0.1.1.tar.gz(r-4.6-any)
metasplines_0.1.1.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION
card.svg |card.png
metasplines/json (API)

# Install 'metasplines' in R:

install.packages('metasplines', repos = c('https://cran.r-universe.dev', 'https://cloud.r-project.org'))

On CRAN:

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

3.00 score 453 downloads 2 exports 64 dependencies

Last updated from:92d7c29869. Checks:4 OK. Indexed: yes.

Target	Result	Time
linux-devel-x86_64	OK	139
source / vignettes	OK	195
linux-release-x86_64	OK	184
wasm-release	OK	133

Exports:pool_all_splines pool_splines

Dependencies:bit bit64 boot cli clipr colorspace CompQuadForm cpp11 crayon digest dplyr farver generics ggplot2 glue gtable hms isoband labeling lattice lifecycle lme4 magrittr MASS mathjaxr Matrix meta metabook metadat metafor minqa nlme nloptr numDeriv optimization pbapply pillar pkgconfig prettyunits progress purrr R6 rbibutils RColorBrewer Rcpp RcppEigen Rdpack readr reformulas rlang S7 scales stringi stringr tibble tidyr tidyselect tzdb utf8 vctrs viridisLite vroom withr xml2

Introduction

Regression analysis using the individual participant data (IPD) | Pool the estimated spline parameters based on the IPD with literature-based (LB) estimates | Plot the IPD, LB and pooled spline estimates

Rendered fromintroduction.Rmdusingknitr::rmarkdown

Last update: 2025-07-21
Started: 2025-07-21

Help page	Topics
Title Pool meta-analysis estimates and estimates from a regression model.	pool_all_splines
Title Pool meta-analysis estimates and estimates from a regression model.	pool_splines

Package: metasplines 0.1.1

metasplines: Pool Literature-Based and Individual Participant Data Based Spline Estimates

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Readme and manuals

Help Manual

Usage by other packages (reverse dependencies)