Package: metasplines Title: Pool Literature-Based and Individual Participant Data Based Spline Estimates Version: 0.1.1 Authors@R: person("Tommi", "Härkänen", , "tommi.harkanen@thl.fi", role = c("aut", "cre")) Author: Tommi Härkänen [aut, cre] Maintainer: Tommi Härkänen Depends: R (>= 4.2.0) Description: Pooling estimates reported in meta-analyses (literature-based, LB) and estimates based on individual participant data (IPD) is not straight-forward as the details of the LB nonlinear function estimate are not usually reported. This package pools the nonlinear IPD dose-response estimates based on a natural cubic spline from lm or glm with the pointwise LB estimates and their estimated variances. Details will be presented in Härkänen, Tapanainen, Sares-Jäske, Männistö, Kaartinen and Paalanen (2026) "Novel pooling method for nonlinear cohort analysis and meta-analysis estimates: Predicting health outcomes based on climate-friendly diets" Epidemiology . License: GPL (>= 3) Encoding: UTF-8 RoxygenNote: 7.3.3 Imports: rlang, dplyr, tidyr, tibble, stringr, meta, optimization Suggests: knitr, rmarkdown, splines2 VignetteBuilder: knitr NeedsCompilation: no Packaged: 2026-07-11 06:30:39 UTC; root Repository: https://cran.r-universe.dev Date/Publication: 2026-01-12 15:00:08 UTC RemoteUrl: https://github.com/cran/metasplines RemoteRef: HEAD RemoteSha: 92d7c29869af32fcbe6bda39be0cf8c9b78dc2bd