Package: UnplanSimon 0.1.0

Introduction | Overview of Simon's Two-Stage Design | Design Parameters and Constraints | Example 1 (Designing a Study Using Simon's Two-Stage Design) | Adaptive Threshold Simon Design (ATS Simon) | Example 2 (ATS Simon design for Addressing Under-or Over-Enrollment in Simon's Two-Stage Design based on Alpha Spending Function) | Example 2.1 (Under-enrollment in $1^{st}$ stage) | Example 2.2 (Under-enrollment in both $1^{st}$ and $2^{nd}$ stages) | Example 2.3 (Under-enrollment in $1^{st}$ and Over-enrollment in $2^{nd}$ stage) | Adaptive Threshold and Sample Size Simon Design (ATSS Simon) | Example 3 (Adaptive Threshold and Sample Size Simon Design (ATSS Simon) for Under- and/or Over-enrollment) | Example 3.1 (Under-enrollment at $1^{st}$ stage) | Example 3.2 (Under-enrollment at $1^{st}$ and $2^{nd}$ stages) | Example 3.3 (Under-enrollment at $1^{st}$ and Over-enrollment at $2^{nd}$ stage) | Summary | Post-Trial Inference for ATS and ATSS Simon Designs with Under- and Over-Enrollment | Point Estimate | Confidence intervals: | $p$-Value: | Example 4 (Post-Trial Inference usage for ATS and ATSS Simon Designs) | Example 4.1 (Post-Trial Inference for ATS Simon Design with Under-Enrollment) | Example 4.2 (Post-Trial Inference for ATSS Simon Design with Under-Enrollment) | References