Package: FBCRM 1.1
Andrew G Chapple
FBCRM: Phase I Optimal Dose Assignment using the FBCRM and MFBCRM Methods
Performs dose assignment and trial simulation for the FBCRM (Fully Bayesian Continual Reassessment Method) and MFBCRM (Mixture Fully Bayesian Continual Reassessment Method) phase I clinical trial designs. These trial designs extend the Continual Reassessment Method (CRM) and Bayesian Model Averaging Continual Reassessment Method (BMA-CRM) by allowing the prior toxicity skeleton itself to be random, with posterior distributions obtained from Markov Chain Monte Carlo. On average, the FBCRM and MFBCRM methods outperformed the CRM and BMA-CRM methods in terms of selecting an optimal dose level across thousands of randomly generated simulation scenarios. Details on the methods and results of this simulation study are available on request, and the manuscript is currently under review.
Authors:
FBCRM_1.1.tar.gz
FBCRM_1.1.tar.gz(r-4.5-noble)FBCRM_1.1.tar.gz(r-4.4-noble)
FBCRM_1.1.tgz(r-4.4-emscripten)FBCRM_1.1.tgz(r-4.3-emscripten)
FBCRM.pdf |FBCRM.html✨
FBCRM/json (API)
# Install 'FBCRM' in R: |
install.packages('FBCRM', repos = c('https://cran.r-universe.dev', 'https://cloud.r-project.org')) |
This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.
Last updated 2 years agofrom:40eb11978c. Checks:OK: 2. Indexed: yes.
Target | Result | Date |
---|---|---|
Doc / Vignettes | OK | Dec 01 2024 |
R-4.5-linux-x86_64 | OK | Dec 01 2024 |
Exports:FBCRMSimTrialGetFBCRMGetMFBCRMMFBCRMSimTrial
Dependencies:RcppRcppArmadillo