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  "Title": "Phase I Optimal Dose Assignment using the FBCRM and MFBCRM\nMethods",
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  "Description": "Performs dose assignment and trial simulation for the\nFBCRM (Fully Bayesian Continual Reassessment Method) and MFBCRM\n(Mixture Fully Bayesian Continual Reassessment Method) phase I\nclinical trial designs. These trial designs extend the\nContinual Reassessment Method (CRM) and Bayesian Model\nAveraging Continual Reassessment Method (BMA-CRM) by allowing\nthe prior toxicity skeleton itself to be random, with posterior\ndistributions obtained from Markov Chain Monte Carlo. On\naverage, the FBCRM and MFBCRM methods outperformed the CRM and\nBMA-CRM methods in terms of selecting an optimal dose level\nacross thousands of randomly generated simulation scenarios.\nDetails on the methods and results of this simulation study are\navailable on request, and the manuscript is currently under\nreview.",
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