Package: BBNI 0.1.1

BBNI: Bayesian Inference of Boolean Genetic Networks

Implements a fully Bayesian Markov chain Monte Carlo (MCMC) approach for inferring the topology and Boolean logic transition functions of gene regulatory networks from noisy, binary time-series expression data. Network structure and Boolean rules are sampled jointly from their posterior distribution, providing principled uncertainty quantification rather than a single point estimate. Method described in Han et al. (2014) <doi:10.1371/journal.pone.0115806>.

Authors:Anson Li [aut, cre], Shengtong Han [aut]