Package: pocrm 0.13
"Brewer, Ben (arb5mt)"
pocrm: Dose Finding in Drug Combination Phase I Trials Using PO-CRM
Provides functions to implement and simulate the partial order continual reassessment method (PO-CRM) of Wages, Conaway and O'Quigley (2011) <doi:10.1177/1740774511408748> for use in Phase I trials of combinations of agents. Provides a function for generating a set of initial guesses (skeleton) for the toxicity probabilities at each combination that correspond to the set of possible orderings of the toxicity probabilities specified by the user.
Authors:
pocrm_0.13.tar.gz
pocrm_0.13.tar.gz(r-4.5-noble)pocrm_0.13.tar.gz(r-4.4-noble)
pocrm_0.13.tgz(r-4.4-emscripten)pocrm_0.13.tgz(r-4.3-emscripten)
pocrm.pdf |pocrm.html✨
pocrm/json (API)
| # Install 'pocrm' in R: |
| install.packages('pocrm', repos = c('https://cran.r-universe.dev', 'https://cloud.r-project.org')) |
This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.
Last updated 3 years agofrom:1cfd9e497d. Checks:OK: 2. Indexed: yes.
| Target | Result | Date |
|---|---|---|
| Doc / Vignettes | OK | Nov 23 2024 |
| R-4.5-linux | OK | Nov 23 2024 |
Readme and manuals
Help Manual
| Help page | Topics |
|---|---|
| Obtain the working models for use in the partial order continual reassessment method (PO-CRM) | getwm |
| Executing the PO-CRM | pocrm.imp |
| Simulating the PO-CRM | pocrm.sim |