Package: pocrm 0.13
"Brewer, Ben (arb5mt)"
pocrm: Dose Finding in Drug Combination Phase I Trials Using PO-CRM
Provides functions to implement and simulate the partial order continual reassessment method (PO-CRM) of Wages, Conaway and O'Quigley (2011) <doi:10.1177/1740774511408748> for use in Phase I trials of combinations of agents. Provides a function for generating a set of initial guesses (skeleton) for the toxicity probabilities at each combination that correspond to the set of possible orderings of the toxicity probabilities specified by the user.
Authors:
pocrm_0.13.tar.gz
pocrm_0.13.tar.gz(r-4.7-any)pocrm_0.13.tar.gz(r-4.6-any)
pocrm_0.13.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
card.svg |card.png
pocrm/json (API)
| # Install 'pocrm' in R: |
| install.packages('pocrm', repos = c('https://cran.r-universe.dev', 'https://cloud.r-project.org')) |
This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.
Last updated from:1cfd9e497d. Checks:4 OK. Indexed: yes.
| Target | Result | Time | Files | Syslog |
|---|---|---|---|---|
| linux-devel-x86_64 | OK | 101 | ||
| source / vignettes | OK | 145 | ||
| linux-release-x86_64 | OK | 116 | ||
| wasm-release | OK | 98 |
Readme and manuals
Help Manual
| Help page | Topics |
|---|---|
| Obtain the working models for use in the partial order continual reassessment method (PO-CRM) | getwm |
| Executing the PO-CRM | pocrm.imp |
| Simulating the PO-CRM | pocrm.sim |