Package: pkr 0.1.6

Kyun-Seop Bae

pkr: Pharmacokinetics in R

Conduct a noncompartmental analysis as closely as possible to the most widely used commercial software. The core noncompartmental computations are delegated to the 'NonCompart' package so that the two share a single, maintained engine. Some features are 1) CDISC SDTM terms 2) Automatic slope selection with the same criterion of WinNonlin(R), restricted by default to samples after the end of an infusion 3) Supporting both 'linear-up linear-down' and 'linear-up log-down' method 4) Interval(partial) AUCs with 'linear' or 'log' interpolation method * Reference: Gabrielsson J, Weiner D. Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications. 5th ed. 2016. (ISBN:9198299107).

Authors:Kyun-Seop Bae [aut, cre], Jee Eun Lee [aut]

pkr_0.1.6.tar.gz
pkr_0.1.6.zip(r-4.7-any)pkr_0.1.6.zip(r-4.6-any)
pkr_0.1.6.tar.gz(r-4.7-any)pkr_0.1.6.tar.gz(r-4.6-any)
pkr_0.1.6.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION |NEWS
card.svg |card.png
pkr/json (API)

# Install 'pkr' in R:

install.packages('pkr', repos = c('https://cran.r-universe.dev', 'https://cloud.r-project.org'))

On CRAN:

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

1.54 score 35 scripts 372 downloads 1 mentions 38 exports 2 dependencies

Last updated from:4d40375a0b. Checks:6 OK. Indexed: yes.

Target	Result	Time
linux-devel	OK	95
source / vignettes	OK	180
linux-release	OK	103
windows-devel	OK	62
windows-release	OK	72
wasm-release	OK	94

Exports:AddPage AUC BestSlope ClosePDF combXPT conv.pp foreNCA IndiNCA IntAUC Interpol LinAUC loadEXPC LogAUC NCA NCA0 Note pdfNCA Plot4rtf plotFit plotPK PrepPDF readEX readPC rNCA Round RptCfg rtfNCA Slope sNCA Subset tblNCA Text1 TextM toproper Trim txtNCA Unit UT

Dependencies:foreign NonCompart

Help page	Topics
Pharmacokinetics in R	pkr-package pkr
Calculate Area Under the Curve (AUC) and Area Under the first Moment Curve (AUMC) in a table format	AUC
Choose best fit slope for the log(y) and x regression by the criteria of adjusted R-square	BestSlope
Combine XPT files	combXPT
Forest plot to compare NCA results	foreNCA
Noncompartmental Analysis for an Individual	IndiNCA
Calculate interval AUC	IntAUC
Interpolate y value	Interpol
Area Under the Curve(AUC) and Area Under the first Moment Curve(AUMC) by linear trapezoidal method	LinAUC
Load EX and PC domain files in folders	loadEXPC
Area Under the Curve(AUC) and Area Under the first Moment Curve(AUMC) by linear-up log-down method	LogAUC
Noncompartmental analysis for a dataset with multiple subjects	NCA
NCA of SDTM data for single subject	NCA0
NCA output to pdf file	pdfNCA
Plot best fit slope	plotFit
Plot concentration vs. time curve for individuals and collectively.	plotPK
Read EX domain files	readEX
Read PC domain files	readPC
Do NCA for review	rNCA
Round Half Away from Zero	Round
NCA Report Configuation Table	RptCfg
NCA output to rtf file	rtfNCA
Get the Slope of regression log(y) ~ x	Slope
Simplest NCA	sNCA
Table output NCA	tblNCA
Text output of NCA for one subject	txtNCA
Disply CDISC standard units and multiplied factor of NCA results	Unit

Package: pkr 0.1.6

pkr: Pharmacokinetics in R

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Help Manual

Usage by other packages (reverse dependencies)