Package: nlmixr2lib 0.3.0

Bill Denney

nlmixr2lib: A Model Library for 'nlmixr2'

A model library for 'nlmixr2'. The models include (and plan to include) pharmacokinetic, pharmacodynamic, and disease models used in pharmacometrics. Where applicable, references for each model are included in the meta-data for each individual model. The package also includes model composition and modification functions to make model updates easier.

Authors:Richard Hooijmaijers [aut], Matthew Fidler [aut], Bill Denney [aut, cre]

nlmixr2lib_0.3.0.tar.gz
nlmixr2lib_0.3.0.tar.gz(r-4.5-noble)nlmixr2lib_0.3.0.tar.gz(r-4.4-noble)
nlmixr2lib_0.3.0.tgz(r-4.4-emscripten)nlmixr2lib_0.3.0.tgz(r-4.3-emscripten)
nlmixr2lib.pdf |nlmixr2lib.html
nlmixr2lib/json (API)
NEWS

# Install 'nlmixr2lib' in R:
install.packages('nlmixr2lib', repos = c('https://cran.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/nlmixr2/nlmixr2lib/issues

Pkgdown:https://nlmixr2.github.io

Datasets:
  • modeldb - Model library for nlmixr2

3.00 score 9 scripts 286 downloads 61 exports 69 dependencies

Last updated 2 months agofrom:b734f71106. Checks:OK: 2. Indexed: no.

TargetResultDate
Doc / VignettesOKDec 07 2024
R-4.5-linuxOKDec 07 2024

Exports:addBaseline1expaddBaselineConstaddBaselineExpaddBaselineLinaddBioavailabilityaddCmtPropaddDepotaddDirectLinaddDirToModelDbaddDuraddEffectCmtLinaddEtaaddFileToModelDbaddIndirectaddIndirectLinaddIniaddLagaddLogEstimatesaddRateaddResErraddTransitaddWeibullAbsassertCompartmentExistsassertCompartmentNameassertParameterValueassertRxUiassertRxUiEstimatedResidualsassertRxUiMixedOnlyassertRxUiMuRefOnlyassertRxUiNormalassertRxUiPopulationOnlyassertRxUiPredictionassertRxUiRandomOnIdOnlyassertRxUiSingleEndpointassertRxUiTransformNormalassertVariableNameblankCombinecamelCombinecombinePaste2convertEmaxconvertEmaxHillconvertKinR0convertLogLinconvertMMconvertQuaddefaultCombinedotCombineexpitfakeCclogitmodellibpkTransreadModelDbremoveDepotremoveLinesAndInisremoveTransitsearchReplacesearchReplaceHelpersetCombineTypesnakeCombineupdateOncologyXenograftSimeoni2004

Dependencies:backportsBHcachemcheckmateclicolorspacecpp11cpp11armadillocrayondata.tabledigestdparserevaluatefansifarverfastmapggplot2gluegtablehighrinlineisobandknitrlabelinglatticelazyevallbfgsb3clifecyclelotrimagrittrMASSMatrixmemoisemgcvminqamunselln1qn1nlmenlmixr2datanlmixr2estnumDerivpillarpkgconfigPreciseSumsqsR6RApiSerializeRColorBrewerRcppRcppArmadilloRcppEigenRcppParallelrexrlangrxode2rxode2llscalessitmoStanHeadersstringfishsymenginesystibbleutf8vctrsviridisLitewithrxfunyaml

Creating a model library

Rendered fromcreate-model-library.Rmdusingknitr::rmarkdownon Dec 07 2024.

Last update: 2024-10-08
Started: 2022-10-31

List of models

Rendered fromlist-of-models.Rmdusingknitr::rmarkdownon Dec 07 2024.

Last update: 2024-10-08
Started: 2024-10-08

Readme and manuals

Help Manual

Help pageTopics
Add baseline that decays exponential with timeaddBaseline1exp
Add an estimated baseline constantaddBaselineConst
Add baseline that decays exponential with timeaddBaselineExp
Add an estimated baseline linear constantaddBaselineLin
Add a property to a compartmentaddBioavailability addCmtProp addDur addIni addLag addRate
To convert from infusion/intravenous administration to first-order oral absorptionaddDepot
Add direct linear effect with baseline=0addDirectLin
Add a directory to the modeldbaddDirToModelDb addFileToModelDb
Add effect compartmentaddEffectCmtLin
Add random effects to a modeladdEta
Add an indirect response model to a PK modeladdIndirect
Add linear indirect response modeladdIndirectLin
Add log estimates to a modeladdLogEstimates
Add residual error to a modeladdResErr
To add transit compartments to the modeladdTransit
Converts first order absorption model to Weibull absorption modeladdWeibullAbs
Combine two strings using a naming conventioncombinePaste2
Convert linear effect to Emax effectconvertEmax
Convert linear effect to Emax-Hill effectconvertEmaxHill
Convert a kin/kout indirect response model to R0 and koutconvertKinR0
Converts a linear effect to a log-linear effectconvertLogLin
Convert models from linear elimination to Michaelis-Menten eliminationconvertMM
Convert linear elimination to quadratic eliminationconvertQuad
Default combine stringsblankCombine camelCombine defaultCombine dotCombine snakeCombine
Fake blank Cc for creating PD only modelsfakeCc
Model library for nlmixr2modeldb
Get the model from the model librarymodellib
Change the transformation type for PK modelspkTrans
Read a model from the nlmixr2 model databasereadModelDb
To convert from first order oral absorption to IV/IntravenousremoveDepot
Removes lines and inis from a modelremoveLinesAndInis
To remove transit compartments from the modelremoveTransit
Search within a model to replace part of the modelsearchReplace searchReplaceHelper
Change the default combine type for the packagesetCombineType
Update an oncology xenograft model based on Simeoni 2004updateOncologyXenograftSimeoni2004