Package: hdmed 1.0.1

Dylan Clark-Boucher

hdmed: Methods for Mediation Analysis with High-Dimensional Mediators

A suite of functions for performing mediation analysis with high-dimensional mediators. In addition to centralizing code from several existing packages for high-dimensional mediation analysis, we provide organized, well-documented functions for a handle of methods which, though programmed their original authors, have not previously been formalized into R packages or been made presentable for public use. The methods we include cover a broad array of approaches and objectives, and are described in detail by both our companion manuscript---"Methods for Mediation Analysis with High-Dimensional DNA Methylation Data: Possible Choices and Comparison"---and the original publications that proposed them. The specific methods offered by our package include the Bayesian sparse linear mixed model (BSLMM) by Song et al. (2019); high-dimensional mediation analysis (HDMA) by Gao et al. (2019); high-dimensional multivariate mediation (HDMM) by Chén et al. (2018); high-dimensional linear mediation analysis (HILMA) by Zhou et al. (2020); high-dimensional mediation analysis (HIMA) by Zhang et al. (2016); latent variable mediation analysis (LVMA) by Derkach et al. (2019); mediation by fixed-effect model (MedFix) by Zhang (2021); pathway LASSO by Zhao & Luo (2022); principal component mediation analysis (PCMA) by Huang & Pan (2016); and sparse principal component mediation analysis (SPCMA) by Zhao et al. (2020). Citations for the corresponding papers can be found in their respective functions.

Authors:Dylan Clark-Boucher [aut, cre], Mike Kleinsasser [aut]

hdmed_1.0.1.tar.gz
hdmed_1.0.1.tar.gz(r-4.5-noble)hdmed_1.0.1.tar.gz(r-4.4-noble)
hdmed_1.0.1.tgz(r-4.4-emscripten)hdmed_1.0.1.tgz(r-4.3-emscripten)
hdmed.pdf |hdmed.html✨
hdmed/json (API)

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10 exports 0.00 score 97 dependencies 7 scripts 868 downloads

Last updated 4 months agofrom:700c87a559. Checks:OK: 1 NOTE: 1. Indexed: yes.

Exports:mediate_bslmmmediate_hdmamediate_hdmmmediate_hilmamediate_himamediate_lvmamediate_medfixmediate_pcmamediate_plassomediate_spcma

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