Package: blisa 1.0.3

Yunshun Chen

blisa: Infer Cell-Cell Communication from Spatial Transcriptomics

Identifies cell-cell communication hotspots in spatial transcriptomics data using bivariate Local Moran's I statistics on hexagonally binned cells. Provides functions for spatial weighting, ligand-receptor pair filtering, hotspot detection, and visualisation of sender-receiver cell-type interactions.

Authors:Yunshun Chen [aut, cre], Lei Qin [aut], Lizhong Chen [aut]

blisa_1.0.3.tar.gz
blisa_1.0.3.zip(r-4.7-any)blisa_1.0.3.zip(r-4.6-any)
blisa_1.0.3.tar.gz(r-4.7-any)blisa_1.0.3.tar.gz(r-4.6-any)
blisa_1.0.3.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION |NEWS
card.svg |card.png
blisa/json (API)

# Install 'blisa' in R:
install.packages('blisa', repos = c('https://cran.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/chenlaboratory/blisa/issues

Pkgdown/docs site:https://chenlaboratory.github.io

On CRAN:

Conda:

3.48 score 1 stars 2 scripts 252 downloads 14 exports 96 dependencies

Last updated from:9643360afa. Checks:6 OK. Indexed: no.

TargetResultTimeFilesSyslog
linux-develOK194
source / vignettesOK252
linux-releaseOK193
windows-develOK131
windows-releaseOK107
wasm-releaseOK175

Exports:blisablisaPathwaycomputeSpatialWeightsfilterLRpairshexBinCellsis.blisaplotCCIplotCCILRplotCCIspatialplotCCIsummaryplotHotspotsplotLRrankrunCCIvisiumSpotBins

Dependencies:abindaskpassBiobaseBiocFileCacheBiocGenericsbitbit64blobbootcachemcirclizeclassclassIntcliclueclustercodetoolscolorspaceComplexHeatmapcpp11crayoncurlDBIdbplyrDelayedArraydeldirdigestdoParalleldplyre1071farverfastLISAfastmapfilelockforeachgenericsGenomicRangesGetoptLongggplot2GlobalOptionsgluegtablehttr2IRangesisobanditeratorsKernSmoothlabelinglatticelifecyclemagickmagrittrMatrixMatrixGenericsmatrixStatsmemoiseopensslpillarpkgconfigpngproxypurrrR6RColorBrewerRcpprjsonrlangRSQLites2S4ArraysS4VectorsS7scalesSeqinfosfshapeSingleCellExperimentspSparseArraySpatialExperimentspDataspdepstringistringrSummarizedExperimentsystibbletidyrtidyselectunitsutf8vctrsviridisLitewithrwkXVector

Exploring cell-cell interaction with blisa
Introduction | Load Package | Load Example Data | Bin Cells into Hexagons | Run BLISA | Rank LR Pairs by Hotspot Count | Spatial Map of Hotspot Bins | Cell-Cell Interaction (CCI) Heatmaps | Across all LR pairs | For a single LR pair | Aggregated across LR pairs | Spatial Map of Dominant Cell-Type Pairs | Session Information
Rendered fromxenium.Rmdusingknitr::rmarkdown

Last update: 2026-10-30
Started: 2026-10-30

Visium profile of human breast tumour
Introduction | Load Package | Load Example Data | Quality control | Run BLISA at the LR level | Run BLISA at the pathway level | Visualization | Spatial Map of Hotspot Bins | Session Information
Rendered fromvisium.Rmdusingknitr::rmarkdown

Last update: 2026-10-30
Started: 2026-10-30