Package: RefBasedMI 0.2.0
RefBasedMI: Reference-Based Imputation for Longitudinal Clinical Trials with Protocol Deviation
Imputation of missing numerical outcomes for a longitudinal trial with protocol deviations. The package uses distinct treatment arm-based assumptions for the unobserved data, following the general algorithm of Carpenter, Roger, and Kenward (2013) <doi:10.1080/10543406.2013.834911>, and the causal model of White, Royes and Best (2020) <doi:10.1080/10543406.2019.1684308>. Sensitivity analyses to departures from these assumptions can be done by the Delta method of Roger. The program uses the same algorithm as the 'mimix' 'Stata' package written by Suzie Cro, with additional coding for the causal model and delta method. The reference-based methods are jump to reference (J2R), copy increments in reference (CIR), copy reference (CR), and the causal model, all of which must specify the reference treatment arm. Other methods are missing at random (MAR) and the last mean carried forward (LMCF). Individual-specific imputation methods (and their reference groups) can be specified.
Authors:
RefBasedMI_0.2.0.tar.gz
RefBasedMI_0.2.0.tar.gz(r-4.5-noble)RefBasedMI_0.2.0.tar.gz(r-4.4-noble)
RefBasedMI.pdf |RefBasedMI.html✨
RefBasedMI/json (API)
# Install 'RefBasedMI' in R: |
install.packages('RefBasedMI', repos = c('https://cran.r-universe.dev', 'https://cloud.r-project.org')) |
Bug tracker:https://github.com/ucl/refbasedmi/issues
- acupuncture - Sample data: acupuncture trial
- antidepressant - Sample data: antidepressant trial
- asthma - Sample data: asthma trial
Last updated 3 months agofrom:bcee397a45. Checks:OK: 2. Indexed: no.
Target | Result | Date |
---|---|---|
Doc / Vignettes | OK | Dec 09 2024 |
R-4.5-linux-x86_64 | OK | Dec 09 2024 |
Exports:RefBasedMI
Dependencies:assertthatbackportsbase64encbitbit64bootbroombslibcachemcheckmateclicliprclustercodetoolscolorspacecpp11crayondata.tabledigestdplyrevaluatefansifarverfastmapfontawesomeforcatsforeachforeignFormulafsgenericsggplot2glmnetgluegridExtragtablehavenhighrHmischmshtmlTablehtmltoolshtmlwidgetsisobanditeratorsjomojquerylibjsonliteknitrlabelinglatticelifecyclelme4magrittrMASSMatrixmemoisemgcvmicemimeminqamitmlmunsellnlmenloptrnnetnumDerivordinalpanpastecspillarpkgconfigprettyunitsprogresspurrrR6rappdirsRColorBrewerRcppRcppEigenreadrrlangrmarkdownrpartrstudioapisassscalesshapestringistringrsurvivaltibbletidyrtidyselecttinytextzdbucminfutf8vctrsviridisviridisLitevroomwithrxfunyaml
Readme and manuals
Help Manual
Help page | Topics |
---|---|
Sample data: acupuncture trial | acupuncture |
Sample data: antidepressant trial | antidepressant |
Sample data: asthma trial | asthma |
Reference-based multiple imputation of longitudinal data | RefBasedMI |