Package: Keyboard 0.1.3

Xiaomeng Yuan

Keyboard: Bayesian Designs for Early Phase Clinical Trials

We developed a package 'Keyboard' for designing single-agent, drug-combination, or phase I/II dose-finding clinical trials. The 'Keyboard' designs are novel early phase trial designs that can be implemented simply and transparently, similar to the 3+3 design, but yield excellent performance, comparable to those of more-complicated, model-based designs (Yan F, Mandrekar SJ, Yuan Y (2017) <doi:10.1158/1078-0432.CCR-17-0220>, Li DH, Whitmore JB, Guo W, Ji Y. (2017) <doi:10.1158/1078-0432.CCR-16-1125>, Liu S, Johnson VE (2016) <doi:10.1093/biostatistics/kxv040>, Zhou Y, Lee JJ, Yuan Y (2019) <doi:10.1002/sim.8475>, Pan H, Lin R, Yuan Y (2020) <doi:10.1016/j.cct.2020.105972>). The 'Keyboard' package provides tools for designing, conducting, and analyzing single-agent, drug-combination, and phase I/II dose-finding clinical trials. For more details about how to use this packge, please refer to Li C, Sun H, Cheng C, Tang L, and Pan H. (2022) "A software tool for both the maximum tolerated dose and the optimal biological dose finding trials in early phase designs". Manuscript submitted for publication.

Authors:Xiaomeng Yuan, Chen Li, Hongying Sun, Li Tang and Haitao Pan

Keyboard_0.1.3.tar.gz
Keyboard_0.1.3.tar.gz(r-4.5-noble)Keyboard_0.1.3.tar.gz(r-4.4-noble)
Keyboard_0.1.3.tgz(r-4.4-emscripten)Keyboard_0.1.3.tgz(r-4.3-emscripten)
Keyboard.pdf |Keyboard.html
Keyboard/json (API)

# Install 'Keyboard' in R:
install.packages('Keyboard', repos = c('https://cran.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

1.60 score 1 stars 3 scripts 196 downloads 4 mentions 16 exports 30 dependencies

Last updated 2 years agofrom:75de0db52b. Checks:OK: 2. Indexed: yes.

TargetResultDate
Doc / VignettesOKNov 05 2024
R-4.5-linuxOKNov 05 2024

Exports:decision.findingexample.kbget.boundary.comb.kbget.boundary.kbget.decision.obd.kbget.decision.obd2.kbget.oc.comb.kbget.oc.kbget.oc.obd.kbget.oc.obd2.kbnext.comb.kbplot_kbselect.mtd.comb.kbselect.mtd.kbselect.obd.kbsummary_kb

Dependencies:clicolorspacefansifarverggplot2gluegtableIsoisobandlabelinglatticelifecyclemagrittrMASSMatrixmgcvmunsellnlmepillarpkgconfigR6RColorBrewerRcpprlangscalestibbleutf8vctrsviridisLitewithr