Package: InterSIM 2.3.0

Prabhakar Chalise

InterSIM: Simulation of Inter-Related Genomic Datasets

Generates three inter-related genomic datasets: methylation, gene expression and protein expression having user specified cluster patterns. The simulation utilizes the realistic inter- and intra- relationships from real DNA methylation, mRNA expression and protein expression data from the TCGA ovarian cancer study, Chalise (2016) <doi:10.1016/j.cmpb.2016.02.011>.

Authors:Prabhakar Chalise [aut, cre], Rama Raghavan [aut], Brooke Fridley [aut]

InterSIM_2.3.0.tar.gz
InterSIM_2.3.0.tar.gz(r-4.5-noble)InterSIM_2.3.0.tar.gz(r-4.4-noble)
InterSIM.pdf |InterSIM.html
InterSIM/json (API)

# Install 'InterSIM' in R:
install.packages('InterSIM', repos = c('https://cran.r-universe.dev', 'https://cloud.r-project.org'))
Datasets:

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

2.81 score 2 packages 36 scripts 473 downloads 3 mentions 15 exports 47 dependencies

Last updated 1 months agofrom:bc55b1e85b. Checks:2 OK. Indexed: yes.

TargetResultLatest binary
Doc / VignettesOKFeb 10 2025
R-4.5-linuxOKFeb 10 2025

Exports:cov.exprcov.Mcov.proteinCpG.gene.map.for.DEGInterSIMlogitmean.exprmean.expr.with.mapped.proteinmean.Mmean.proteinmethyl.gene.level.meanprotein.gene.map.for.DEPrev.logitrho.expr.proteinrho.methyl.expr

Dependencies:BiobaseBiocGenericsBiocManagercliclustercodetoolscolorspacedigestdoParallelfansifarverforeachgenericsggplot2gluegridBasegtableisobanditeratorslabelinglatticelifecyclemagrittrMASSMatrixmgcvmunsellnlmeNMFpillarpkgconfigplyrR6RColorBrewerRcppregistryreshape2rlangrngtoolsscalesstringistringrtibbleutf8vctrsviridisLitewithr

Readme and manuals

Help Manual

Help pageTopics
Simulation of inter-related genomic datasetsInterSIM-package
InterSIMcov.expr cov.M cov.protein CpG.gene.map.for.DEG InterSIM logit mean.expr mean.expr.with.mapped.protein mean.M mean.protein methyl.gene.level.mean protein.gene.map.for.DEP rev.logit rho.expr.protein rho.methyl.expr