Package: GEVACO 1.0.1
Sydney Manning
GEVACO: Joint Test of Gene and GxE Interactions via Varying Coefficients
A novel statistical model to detect the joint genetic and dynamic gene-environment (GxE) interaction with continuous traits in genetic association studies. It uses varying-coefficient models to account for different GxE trajectories, regardless whether the relationship is linear or not. The package includes one function, GxEtest(), to test a single genetic variant (e.g., a single nucleotide polymorphism or SNP), and another function, GxEscreen(), to test for a set of genetic variants. The method involves a likelihood ratio test described in Crainiceanu, C. M., and Ruppert, D. (2004) <doi:10.1111/j.1467-9868.2004.00438.x>.
Authors:
GEVACO_1.0.1.tar.gz
GEVACO_1.0.1.tar.gz(r-4.5-noble)GEVACO_1.0.1.tar.gz(r-4.4-noble)
GEVACO_1.0.1.tgz(r-4.4-emscripten)GEVACO_1.0.1.tgz(r-4.3-emscripten)
GEVACO.pdf |GEVACO.html✨
GEVACO/json (API)
| # Install 'GEVACO' in R: |
| install.packages('GEVACO', repos = c('https://cran.r-universe.dev', 'https://cloud.r-project.org')) |
- cov_example - Covariate Information
- geno_example - Genotypic Information
This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.
Last updated 3 years agofrom:dc0079dfbd. Checks:OK: 1 WARNING: 1. Indexed: yes.
| Target | Result | Date |
|---|---|---|
| Doc / Vignettes | OK | Oct 27 2024 |
| R-4.5-linux | WARNING | Oct 27 2024 |
Dependencies:bootlatticelme4MASSMatrixmgcvminqanlmenloptrRcppRcppEigenRLRsim
Readme and manuals
Help Manual
| Help page | Topics |
|---|---|
| Covariate Information | cov_example |
| Genotypic Information | geno_example |
| Gene-Environment Interaction: Genome-wide Screen | GxEscreen |
| Joint test for genetic and gene-environment interaction effects for a single SNP | GxEtest |