Package: EWOC.Comb 1.0

Yujie Cui
EWOC.Comb: Escalation with Overdose Control using 2 Drug Combinations
Implements Escalation With Overdose Control trial designs using two drug combinations described by this paper <doi:10.1002/sim.6961>(Tighiouart et al., 2016). It calculates the recommended dose for next cohorts and perform simulations to obtain operating characteristics.
Authors:
EWOC.Comb_1.0.tar.gz
EWOC.Comb_1.0.tar.gz(r-4.5-noble)EWOC.Comb_1.0.tar.gz(r-4.4-noble)
EWOC.Comb_1.0.tgz(r-4.4-emscripten)EWOC.Comb_1.0.tgz(r-4.3-emscripten)
EWOC.Comb.pdf |EWOC.Comb.html✨
EWOC.Comb/json (API)
# Install 'EWOC.Comb' in R: |
install.packages('EWOC.Comb', repos = 'https://cloud.r-project.org') |
This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.
Last updated 9 months agofrom:96b8948462. Checks:3 OK. Indexed: yes.
Target | Result | Latest binary |
---|---|---|
Doc / Vignettes | OK | Mar 26 2025 |
R-4.5-linux | OK | Mar 26 2025 |
R-4.4-linux | OK | Mar 26 2025 |
Citation
To cite package ‘EWOC.Comb’ in publications use:
Yujie Cui, Quanlin Li, Mourad Tighiouart (2024). EWOC.Comb: Escalation with Overdose Control using 2 Drug Combinations. R package version 1.0, https://CRAN.R-project.org/package=EWOC.Comb.
Corresponding BibTeX entry:
@Manual{, title = {EWOC.Comb: Escalation with Overdose Control using 2 Drug Combinations}, author = {{Yujie Cui} and {Quanlin Li} and {Mourad Tighiouart}}, year = {2024}, note = {R package version 1.0}, url = {https://CRAN.R-project.org/package=EWOC.Comb}, }
Readme and manuals
Help Manual
Help page | Topics |
---|---|
Escalation with Overdose Control using 2 Drug Combinations | EWOC.Comb-package EWOC.Comb |
Escalation With Overdose Control for two drugs combination | ewoc2 ewoc2.default |
Generic EWOC2 simulation | ewoc2simu ewoc2simu.default |
Generating MTD curve based on logistic model for two drugs | mtdcurve |
Generating probability of DLT based on the EWOC2 model | pdlt |
EWOC for 2 drugs combination trial design characteristics | plot.ewoc2simu |
Summarizing EWOC2 next doses results | print.ewoc2 |
Summarizing EWOC2 simulation results | print.ewoc2simu |