Package: Allspice 1.0.7

Ville-Petteri Makinen

Allspice: RNA-Seq Profile Classifier

We developed a lightweight machine learning tool for RNA profiling of acute lymphoblastic leukemia (ALL), however, it can be used for any problem where multiple classes need to be identified from multi-dimensional data. The methodology is described in Makinen V-P, Rehn J, Breen J, Yeung D, White DL (2022) Multi-cohort transcriptomic subtyping of B-cell acute lymphoblastic leukemia, International Journal of Molecular Sciences 23:4574, <doi:10.3390/ijms23094574>. The classifier contains optimized mean profiles of the classes (centroids) as observed in the training data, and new samples are matched to these centroids using the shortest Euclidean distance. Centroids derived from a dataset of 1,598 ALL patients are included, but users can train the models with their own data as well. The output includes both numerical and visual presentations of the classification results. Samples with mixed features from multiple classes or atypical values are also identified.

Authors:Ville-Petteri Makinen [aut, cre]

Allspice_1.0.7.tar.gz
Allspice_1.0.7.tar.gz(r-4.5-noble)Allspice_1.0.7.tar.gz(r-4.4-noble)
Allspice_1.0.7.tgz(r-4.4-emscripten)Allspice_1.0.7.tgz(r-4.3-emscripten)
Allspice.pdf |Allspice.html
Allspice/json (API)

# Install 'Allspice' in R:
install.packages('Allspice', repos = c('https://cran.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

2.00 score 357 downloads 18 exports 0 dependencies

Last updated 2 years agofrom:0c2e0b380d. Checks:OK: 2. Indexed: yes.

TargetResultDate
Doc / VignettesOKNov 18 2024
R-4.5-linuxOKNov 18 2024

Exports:assemble<-assetbcellALLclassifierclassifyconfigurationconfiguration<-covariates<-exportinformationnomenclature<-normalizepredictionsprofiles<-reportscoresstandardizevisuals<-

Dependencies:

Introduction to Allspice

Rendered fromintro.rmdusingknitr::rmarkdownon Nov 18 2024.

Last update: 2023-01-20
Started: 2022-02-18

Readme and manuals

Help Manual

Help pageTopics
Finish Asset contentsassemble assemble,Asset-method assemble<- assemble<-,Asset-method
Constructor for Assetasset Asset-class
Simulated databcellALL
Constructor for Classifierclassifier Classifier-class
Data classificationclassify classify,Asset-method
Asset configurationconfiguration configuration,Asset-method configuration<- configuration<-,Asset-method
Sample covariate datacovariates covariates,Classifier-method covariates<- covariates<-,Classifier-method
Data classificationexport export,Asset-method
Classifier contentsinformation information,Classifier-method
Variable namesnomenclature nomenclature,Asset-method nomenclature<- nomenclature<-,Asset-method
Sample normalizationnormalize normalize,Asset-method
Category predictionspredictions predictions,Classifier-method
Sample data profilesprofiles profiles<- profiles<-,Classifier-method
Visualization of resultsreport report,Classifier-method
Category scoresscores scores,Classifier-method
Data standardizationstandardize standardize,Asset-method
Visual attributesvisuals visuals,Asset-method visuals<- visuals<-,Asset-method