Package: segregatr 0.4.0
Magnus Dehli Vigeland
segregatr:Segregation Analysis for Variant Interpretation
An implementation of the full-likelihood Bayes factor (FLB) for evaluating segregation evidence in clinical medical genetics. The method was introduced by Thompson et al. (2003) <doi:10.1086/378100>. This implementation supports custom penetrance values and liability classes, and allows visualisations and robustness analysis as presented in Ratajska et al. (2023) <doi:10.1002/mgg3.2107>. See also the online app 'shinyseg', <https://chrcarrizosa.shinyapps.io/shinyseg>, which offers interactive segregation analysis with many additional features (Carrizosa et al. (2024) <doi:10.1093/bioinformatics/btae201>).
Authors:
segregatr_0.4.0.tar.gz
segregatr_0.4.0.tar.gz(r-4.5-noble)segregatr_0.4.0.tar.gz(r-4.4-noble)
segregatr_0.4.0.tgz(r-4.4-emscripten)segregatr_0.4.0.tgz(r-4.3-emscripten)
segregatr.pdf |segregatr.html✨
segregatr/json (API)
NEWS
| # Installsegregatr in R: |
| install.packages('segregatr',repos = c('https://cran.r-universe.dev', 'https://cloud.r-project.org')) |
Bug tracker:https://github.com/magnusdv/segregatr/issues
Last updated 7 days agofrom:ad8ada7420
Exports:FLBplotSegregation
Dependencies:evaluatehighrkinship2knitrlatticeMatrixpedmutpedprobrpedtoolsquadprogxfunyaml
Readme and manuals
Help Manual
| Help page | Topics |
|---|---|
| Full-likelihood Bayes factor | FLB |
| Pedigree plot for segregation analysis | plotSegregation |