Package: topologyGSA Version: 1.5.0 Date: 2023-09-25 Title: Gene Set Analysis Exploiting Pathway Topology Author: Sofia Massa, Gabriele Sales Maintainer: Gabriele Sales Description: Using Gaussian graphical models we propose a novel approach to perform pathway analysis using gene expression. Given the structure of a graph (a pathway) we introduce two statistical tests to compare the mean and the concentration matrices between two groups. Specifically, these tests can be performed on the graph and on its connected components (cliques). The package is based on the method described in Massa M.S., Chiogna M., Romualdi C. (2010) . Imports: graph, gRbase (>= 2.0), qpgraph, fields, methods, igraph Suggests: Rgraphviz License: GPL-3 LazyLoad: yes biocViews: NeedsCompilation: no Packaged: 2026-10-03 08:19:21 UTC; root Config/pak/sysreqs: libbz2-dev liblzma-dev libssl-dev xz-utils zlib1g-dev Repository: https://cran.r-universe.dev Date/Publication: 2023-09-25 19:30:42 UTC RemoteUrl: https://github.com/cran/topologyGSA RemoteRef: HEAD RemoteSha: 68c5de177606a4fc304a133147664c13b5bc3f98