# -------------------------------------------- # CITATION file created with {cffr} R package # See also: https://docs.ropensci.org/cffr/ # -------------------------------------------- cff-version: 1.2.0 message: 'To cite package "tlsR" in publications use:' type: software license: MIT title: 'tlsR: Detection and Spatial Analysis of Tertiary Lymphoid Structures' version: 0.3.0 doi: 10.32614/CRAN.package.tlsR abstract: Fast, reproducible detection and quantitative analysis of tertiary lymphoid structures (TLS) in multiplexed tissue imaging. Implements Independent Component Analysis Trace (ICAT) index, local Ripley's K scanning, automated K Nearest Neighbor (KNN)-based TLS detection, and T-cell clusters identification as described in Amiryousefi et al. (2025) . authors: - family-names: Amiryousefi given-names: Ali email: ali_amiryousefi@hms.harvard.edu orcid: https://orcid.org/0000-0002-6317-3860 - family-names: Wala given-names: Jeremiah email: jeremiah_wala@dfci.harvard.edu orcid: https://orcid.org/0000-0001-6591-1620 repository: https://cran.r-universe.dev repository-code: https://github.com/labsyspharm/tlsR commit: b0b0fc313de9296349ed3d052363c19e058d5aa5 url: https://github.com/labsyspharm/tlsR date-released: '2026-04-02' contact: - family-names: Amiryousefi given-names: Ali email: ali_amiryousefi@hms.harvard.edu orcid: https://orcid.org/0000-0002-6317-3860