Package: sctransform Type: Package Title: Variance Stabilizing Transformations for Single Cell UMI Data Version: 0.4.3 Date: 2025-12-25 Authors@R: c( person(given = "Christoph", family = "Hafemeister", email = "christoph.hafemeister@nyu.edu", role = "aut", comment = c(ORCID = "0000-0001-6365-8254")), person(given = "Saket", family = "Choudhary", email = "saketc@iitb.ac.in", role = c("aut", "cre"), comment = c(ORCID = "0000-0001-5202-7633")), person(given = "Rahul", family = "Satija", email = "rsatija@nygenome.org", role = "ctb", comment = c(ORCID = "0000-0001-9448-8833")) ) Description: A normalization method for single-cell UMI count data using a variance stabilizing transformation. The transformation is based on a negative binomial regression model with regularized parameters. As part of the same regression framework, this package also provides functions for batch correction, and data correction. See Hafemeister and Satija (2019) , and Choudhary and Satija (2022) for more details. URL: https://github.com/satijalab/sctransform BugReports: https://github.com/satijalab/sctransform/issues License: GPL-3 | file LICENSE Encoding: UTF-8 LazyData: true Depends: R (>= 3.6.0) LinkingTo: RcppArmadillo, Rcpp (>= 0.11.0) SystemRequirements: C++17 Imports: dplyr, magrittr, MASS, Matrix (>= 1.5-0), methods, future.apply, future, parallelly, ggplot2, reshape2, rlang, gridExtra, matrixStats Suggests: irlba, testthat, knitr Enhances: glmGamPoi RoxygenNote: 7.3.3 NeedsCompilation: yes Packaged: 2026-10-28 08:34:02 UTC; root Author: Christoph Hafemeister [aut] (ORCID: ), Saket Choudhary [aut, cre] (ORCID: ), Rahul Satija [ctb] (ORCID: ) Maintainer: Saket Choudhary Repository: https://cran.r-universe.dev Date/Publication: 2026-01-10 08:45:16 UTC RemoteUrl: https://github.com/cran/sctransform RemoteRef: HEAD RemoteSha: 18ab33de11b98a0f857df234c0ac7eb347cad3db