Package: scaRabee Type: Package Title: Optimization Toolkit for Pharmacokinetic-Pharmacodynamic Models Version: 1.1-5 Date: 2026-01-25 Authors@R: person("Sebastien","Bihorel",role=c("aut","cre"),email="sb.pmlab@gmail.com") Depends: neldermead (>= 1.0-8), optimsimplex (>= 1.0-5), optimbase (>= 1.0-8) Imports: lattice, grid, deSolve, utils, methods Suggests: knitr (>= 1.28),rmarkdown (>= 2.2) Description: A port of the Scarabee toolkit originally written as a Matlab-based application. scaRabee provides a framework for simulation and optimization of pharmacokinetic-pharmacodynamic models at the individual and population level. It is built on top of the neldermead package, which provides the direct search algorithm proposed by Nelder and Mead for model optimization. License: GPL-3 Encoding: UTF-8 VignetteBuilder: knitr LazyLoad: yes NeedsCompilation: no Packaged: 2026-07-03 16:08:38 UTC; root Author: Sebastien Bihorel [aut, cre] Maintainer: Sebastien Bihorel Repository: https://cran.r-universe.dev Date/Publication: 2026-01-25 22:50:03 UTC RemoteUrl: https://github.com/cran/scaRabee RemoteRef: HEAD RemoteSha: 925eb6d34b1a917ad38b22a1a00d82b05fb79bae