NEWS

rsynthbio 4.2.0 (2026-06-12)

Added self-hosted model support: predict_query() and get_example_query() gain a self_hosted argument (also resolved from the SYNTHESIZE_SELF_HOSTED environment variable). When enabled, the client sends a single synchronous request to a partner-hosted model container and decodes the Apache Arrow IPC stream response into the same data frames as the production path (no polling, no download URL). Requires the optional arrow package; no API key is required (one is only sent when SYNTHESIZE_API_KEY is set).
Added per-model base-URL resolution: set SYNTHESIZE_API_BASE_URL__<MODEL> (e.g. SYNTHESIZE_API_BASE_URL__GEM_1_BULK) to point each model at its own self-hosted container once and omit api_base_url on every call. Resolution precedence is: explicit api_base_url -> per-model variable -> global SYNTHESIZE_API_BASE_URL -> production default.
Self-hosted predictions use a longer 600s request timeout to accommodate large sample counts on partner GPU hosts.

predict_query() now raises an error when called with a model_id that has no registered output transformer. Pass raw_response = TRUE to get the unformatted JSON response.
Metadata prediction models (gem-1-bulk_predict-metadata, gem-1-sc_predict-metadata) now return a named list with metadata, latents, classifier_probs, and expression data.frames instead of the raw outputs list.

Added output transformer for gem-1-bulk_predict-metadata and gem-1-sc_predict-metadata that converts results to data.frames.
Added output transformer for gem-1-bulk_condition-on-sample-ids.