Package: revert
Type: Package
Title: Reversion Mutation Detector for DNA Sequencing Data
Version: 1.0.0
Date: 2025-12-16
Authors@R: c(
	person("Hui", "Xiao", role = c("aut", "cre"), email = "hui.xiao@icr.ac.uk"),
	person("Stephen", "Pettitt", role = "aut", email = "stephen.pettitt@icr.ac.uk"),
	person("Syed", "Haider", role = c("aut"), email = "Syed.Haider@icr.ac.uk")
  )
Author: Hui Xiao [aut, cre], Stephen Pettitt [aut], Syed Haider [aut]
Maintainer: Hui Xiao <hui.xiao@icr.ac.uk>
Description: Reversion mutations are secondary mutations that reverse
        the deleterious effects of an original pathogenic mutation,
        partially or fully restoring the gene's function. The revert
        package detects reversion mutations for a specific pathogenic
        mutation from DNA-seq bam files.
Depends: R (>= 4.4.0)
License: GPL-2
Imports: BSgenome, BiocGenerics, Biostrings, GenomeInfoDb,
        GenomicRanges, IRanges, Rsamtools, S4Vectors, ensembldb,
        pwalign, stats, utils
Suggests: knitr, rmarkdown, futile.logger, BSgenome.Hsapiens.UCSC.hg19,
        EnsDb.Hsapiens.v75, BSgenome.Hsapiens.UCSC.hg38,
        EnsDb.Hsapiens.v86
RoxygenNote: 7.3.2
Encoding: UTF-8
VignetteBuilder: knitr
NeedsCompilation: no
Packaged: 2026-07-03 11:02:20 UTC; root
Config/pak/sysreqs: libbz2-dev liblzma-dev libssl-dev xz-utils
        zlib1g-dev
Repository: https://cran.r-universe.dev
Date/Publication: 2025-12-17 23:30:02 UTC
RemoteUrl: https://github.com/cran/revert
RemoteRef: HEAD
RemoteSha: be2c826183d54eed19555bca0659542a9e0497ca