Title: | Meta-Analysis Methods Correcting for Publication Bias |
---|---|
Description: | Provides meta-analysis methods that correct for publication bias and outcome reporting bias. Four methods and a visual tool are currently included in the package. The p-uniform method as described in van Assen, van Aert, and Wicherts (2015) <doi:10.1037/met0000025> can be used for estimating the average effect size, testing the null hypothesis of no effect, and testing for publication bias using only the statistically significant effect sizes of primary studies. The second method in the package is the p-uniform* method as described in van Aert and van Assen (2023) <doi:10.31222/osf.io/zqjr9>. This method is an extension of the p-uniform method that allows for estimation of the average effect size and the between-study variance in a meta-analysis, and uses both the statistically significant and nonsignificant effect sizes. The third method in the package is the hybrid method as described in van Aert and van Assen (2018) <doi:10.3758/s13428-017-0967-6>. The hybrid method is a meta-analysis method for combining a conventional study and replication/preregistered study while taking into account statistical significance of the conventional study. This method was extended in van Aert (2023) such that it allows for the inclusion of multiple conventional and replication/preregistered studies. The p-uniform and hybrid method are based on the statistical theory that the distribution of p-values is uniform conditional on the population effect size. The fourth method in the package is the Snapshot Bayesian Hybrid Meta-Analysis Method as described in van Aert and van Assen (2018) <doi:10.1371/journal.pone.0175302>. This method computes posterior probabilities for four true effect sizes (no, small, medium, and large) based on an original study and replication while taking into account publication bias in the original study. The method can also be used for computing the required sample size of the replication akin to power analysis in null-hypothesis significance testing. The meta-plot is a visual tool for meta-analysis that provides information on the primary studies in the meta-analysis, the results of the meta-analysis, and characteristics of the research on the effect under study (van Assen et al., 2023). Helper functions to apply the Correcting for Outcome Reporting Bias (CORB) method to correct for outcome reporting bias in a meta-analysis (van Aert & Wicherts, 2023). |
Authors: | Robbie C.M. van Aert |
Maintainer: | Robbie C.M. van Aert <[email protected]> |
License: | GPL (>= 2) |
Version: | 0.2.7 |
Built: | 2024-11-12 06:44:27 UTC |
Source: | CRAN |
Results from 12 studies on the association between infants' habituation to a give stimulus and their later cognitive ability (IQ).
The data frame contains two columns: ri (raw correlation coefficients) and ni (sample sizes).
Robbie C.M. van Aert [email protected]
McCall, R. B., & Carriger, M. S. (1993). A meta-analysis of infant habituation and recognition memory performance as predictors of later IQ. Child Development, 64, 57-79. http://dx.doi.org/10.2307/1131437
Function for computing posterior probabilities based on the Snapshot Bayesian Hybrid Meta-Analysis Method or Snapshot Bayesian Meta-Analysis Method (uncorrected) for another than a uniform prior.
diffprior(prior, res.snap)
diffprior(prior, res.snap)
prior |
A vector of length four containing the prior probabilities for no, small, medium, and large true effect size. |
res.snap |
A data frame with posterior probabilities obtained with the
|
The function computes posterior probabilities for four true effect
sizes (no, small, medium, and large) based on the snapshot
or
uncor.snapshot
function for another than a uniform prior. For more
information see van Aert and van Assen (2016).
The diffprior
function returns a data frame with posterior probabilities
for no (p.0
), small (p.sm
), medium (p.me
), and large (p.la
)
true effect size.
Robbie C.M. van Aert [email protected]
van Aert, R.C.M. & van Assen, M.A.L.M. (2017). Bayesian evaluation of effect size after replicating an original study. PLoS ONE, 12(4), e0175302. doi:10.1371/journal.pone.0175302
### Example as presented on page 491 in Maxwell, Lau, and Howard (2015) res.snap <- snapshot(ri=c(0.243, 0.114), ni=c(80, 172), alpha=.05) ### Prior probabilities with probablity for no effect twice as large as for the other true effects prior <- c(0.4, 0.2, 0.2, 0.2) ### Compute posterior probabilities based on new prior diffprior(prior = prior, res.snap = res.snap)
### Example as presented on page 491 in Maxwell, Lau, and Howard (2015) res.snap <- snapshot(ri=c(0.243, 0.114), ni=c(80, 172), alpha=.05) ### Prior probabilities with probablity for no effect twice as large as for the other true effects prior <- c(0.4, 0.2, 0.2, 0.2) ### Compute posterior probabilities based on new prior diffprior(prior = prior, res.snap = res.snap)
Function that computes Hedges' g and its sampling variance for an one-sample mean and a two-independent means, Fisher's r-to-z transformed correlation coefficient and its sampling variance for a raw correlation coefficient and computes a p-value as in the primary studies was done.
escompute( mi, ri, ni, sdi, m1i, m2i, n1i, n2i, sd1i, sd2i, tobs, yi, vi, alpha, side, measure )
escompute( mi, ri, ni, sdi, m1i, m2i, n1i, n2i, sd1i, sd2i, tobs, yi, vi, alpha, side, measure )
mi |
A vector of group means for one-sample mean |
ri |
A vector of raw correlation coefficients |
ni |
A vector of sample sizes for one-sample mean |
sdi |
A vector of standard deviations for one-sample mean |
m1i |
A vector of means in group 1 for two-independent means |
m2i |
A vector of means in group 2 for two-independent means |
n1i |
A vector of sample sizes in group 1 for two-independent means |
n2i |
A vector of sample sizes in group 2 for two-independent means |
sd1i |
A vector of standard deviations in group 1 for two-independent means |
sd2i |
A vector of standard deviations in group 2 for two-independent means |
tobs |
A vector of t-values |
yi |
A vector of standardized effect sizes |
vi |
A vector of sampling variances belonging to the standardized effect sizes ( |
alpha |
A numerical value specifying the alpha level as used in primary studies |
side |
A character indicating the direction of the tested hypothesis in the primary studies (either " |
measure |
A character indicating what kind of effect size should be computed (Hedges' g or Fisher's r-to-z transformed correlation coefficients) and which arguments are used as input (" |
The measure
argument has to be used to specify the desired effect size and what input parameters are used. There are six options:
"M"
for one-sample mean with mi
, ni
, sdi
, alpha
, and side
as input parameters
"MT"
for one-sample mean with tobs
, ni
, alpha
, and side
as input parameters
"MD"
for two-sample mean with m1i
, m2i
, n1i
, n2i
, sd1i
, sd2i
, alpha
, and side
as input parameters
"MDT"
for two-sample mean with tobs
, n1i
, n2i
, alpha
, and side
as input parameters
"COR"
for raw correlation coefficients with ri
, ni
, alpha
, and side
as input parameters
"SPE"
for user-specified standardized effect sizes and sampling variances with yi
, vi
, alpha
, and side
as input parameters
Function returns a data frame with standardized effect sizes (yi), variances of these standardized effect sizes (vi), z-values (zval), p-values as computed in primary studies (pval), and critical z-values (zcv).
Robbie C.M. van Aert [email protected]
Function that conducts fixed-effect meta-analysis
fe_ma(yi, vi)
fe_ma(yi, vi)
yi |
A vector of standardized effect sizes |
vi |
A vector of sampling variances belonging to the standardized effect sizes ( |
The fe.ma
function can be used for conducting fixed-effect meta-analysis
on a set of studies
est.fe |
effect size estimate of fixed-effect meta-analysis |
se.fe |
standard error of estimate of fixed-effect meta-analysis |
ci.lb.fe |
lower bound 95% confidence interval |
ci.ub.fe |
upper bound 95% confidence interval |
zval.fe |
z-value of test of no effect |
pval.fe |
two-tailed p-value of test of no effect |
pval.fe.one |
one-tailed p-value of test of no effect |
Qstat |
test statistic of the Q-test |
Qpval |
p-value of the Q-test |
Function for transforming raw correlation coefficients to Fisher-z transformed correlation coefficients and vice versa.
fis_trans(r, fis)
fis_trans(r, fis)
r |
A numerical value being a raw correlation coefficient |
fis |
A numerical value being a Fisher-z transformed correlation coefficient |
Robbie C.M. van Aert [email protected]
Function to statistically combine conventional and preregistered/replications studies by means of the hybrid methods as described in van Aert and van Assen (2018) and van Aert (2023).
hybrid( m1i, m2i, mi, ri, sd1i, sd2i, sdi, n1i, n2i, ni, tobs, yi, vi, conventional, mods = NULL, alpha = 0.05, side, control )
hybrid( m1i, m2i, mi, ri, sd1i, sd2i, sdi, n1i, n2i, ni, tobs, yi, vi, conventional, mods = NULL, alpha = 0.05, side, control )
m1i |
A vector of means in group 1 for two-independent means |
m2i |
A vector of means in group 2 for two-independent means |
mi |
A vector of group means for one-sample means |
ri |
A vector of raw correlations |
sd1i |
A vector of standard deviations in group 1 for two-independent means |
sd2i |
A vector of standard deviations in group 2 for two-independent means |
sdi |
A vector of standard deviations for one-sample means |
n1i |
A vector of sample sizes in group 1 for two-independent means |
n2i |
A vector of sample sizes in group 2 for two-independent means |
ni |
A vector of sample sizes for one-sample means and correlations |
tobs |
A vector of t-values |
yi |
A vector of standardized effect sizes (see Details) |
vi |
A vector of sampling variances belonging to the standardized effect sizes (see Details) |
conventional |
A vector indicating whether a study is a conventional study (indicated with a 1) and therefore was susceptible to bias. Studies not susceptible to bias are indicated with a 0 |
mods |
A one-sided formula to specify the moderators to include. For
example |
alpha |
A numerical value specifying the alpha level as used in the conventional study (default is 0.05, see Details) |
side |
A character indicating whether the observed effect size of the
conventional studies are in the right-tail of the distribution (i.e., positive) or
in the left-tail of the distribution (i.e., negative) (either |
control |
An optional list of elements that give the user more control over the estimation procedures (see Note) |
Three different effect sizes can be used as input for the
hybrid
function: one-sample means, two-independent means, and raw
correlation coefficients. Analyzing one-sample means and two-independent
means can be done by either providing the function group means (mi
or
m1i
and m2i
), standard deviations (sdi
or sd1i
and sd2i
), and sample sizes (ni
or n1i
and n2i
)
or t-values (tobs
) and sample sizes (ni
or n1i
and n2i
). Pearson correlation coefficients can be analyzed by supplying
ri
and ni
to the hybrid
function. These correlation
coefficients are internally transformed to Fisher's z correlations before
analyzing the data. The results in the output are of the Fisher's z transformed
correlations. It is also possible to specify the standardized effect sizes and
its sampling variances directly via the yi
and vi
arguments.
Two other arguments that need to be specified are side
and conventional
.
side
indicates whether the effect size in the conventional study was expected
to be in the right-tail (side = "right"
or in the left-tail
(side = "left"
) of the distribution. The argument conventional
has
to be used to indicate which studies are conventional studies and expected to be
susceptible to bias. A 1 indicates that a study was susceptible to bias and
a 0 indicates that a study was not susceptible to bias.
It is assumed that two-tailed hypothesis tests were conducted in the conventional
studies. In case one-tailed hypothesis tests were conducted in the conventional
studies, the alpha level has to be multiplied by two. For example, if one-tailed
hypothesis tests were conducted with an alpha level of .05, an alpha of 0.1
has to be supplied to the hybrid
function.
Previous version
The usage of a previous version of the hybrid
function was more restricted.
Users could only apply the method to a single conventional study and replication.
Before the addition of the extra functionality to also analyze multiple conventional
studies and replications, data of the conventional study and replication were
specified in vectors containing two elements with the first element being
the data of the conventional study and the second one the data of the replication.
In order to maintain backwards compatibility, it is still possible to analyze
data like this by using the arguments m1i, m2i, mi, ri, sd1i, sd2i, sdi,
n1i, n2i, ni, tobs
. However, using the hybrid
function in this way is
now deprecated.
k |
total number of effect sizes |
k.conventional |
number of effect sizes of conventional studies |
est |
parameter estimates of the fixed effects of the hybrid method |
tau2 |
estimate of the between-study variance in true effect size of hybrid method |
se |
standard error of the fixed effects and of the estimated between-study variance |
ci.lb |
lower bound of hybrid method's confidence interval of the average effect size |
ci.ub |
upper bound of hybrid method's confidence interval of the average effect size |
L.0 |
test statistic of hybrid method's test of null-hypothesis of no
effect. This is either a z-value ( |
pval.0 |
p-value of hybrid method's test of null-hypothesis of no effect |
tau2 |
estimate of the between-study variance in true effect size of hybrid method |
tau2.lb |
lower bound of hybrid method's confidence interval of the between-study variance |
tau2.ub |
upper bound of hybrid method's confidence interval of the between-study variance |
L.het |
test statistic of hybrid method's test of null-hypothesis of no
heterogeneity This is either a z-value ( |
pval.het |
p-value of hybrid method's test of null-hypothesis of no heterogeneity |
optim.info |
model fitting results if the implementation of van Aert (2023) is used |
The elements below are only returned if the deprecated implementation of van Aert and van Assen (2018) is used:
est.hyr |
effect size estimate of hybridR method |
ci.lb.hyr |
lower bound of hybridR method's confidence interval of the effect size |
ci.ub.hyr |
upper bound of hybridR method's confidence interval of the effect size |
L.0.hyr |
test statistic of hybridR method's test of null-hypothesis of no effect |
pval.0.hyr |
p-value of hybridR method's test of null-hypothesis of no effect |
pval.o |
two-tailed p-value of conventional study |
est.hy0 |
effect size estimate of hybrid0 method |
ci.lb.hy0 |
lower bound of hybrid0 method's confidence interval of the effect size |
ci.ub.hy0 |
upper bound of hybrid0 method's confidence interval of the effect size |
L.0.hy0 |
test statistic of hybrid0 method's test of null-hypothesis of no effect |
pval.0.hy0 |
two-tailed p-value of hybrid0 method's test of null-hypothesis of no effect |
est.fe |
effect size estimate based on fixed-effect meta-analysis |
se.fe |
standard error of effect size estimate based on traditional fixed-effect meta-analysis |
zval.fe |
test statistic of the null-hypothesis of no effect based on fixed-effect meta-analysis |
pval.fe |
two-tailed p-value of the null-hypothesis of no effect based on fixed-effect meta-analysis |
ci.lb.fe |
lower bound of confidence interval based on traditional fixed-effect meta-analysis |
ci.ub.fe |
upper bound of confidence interval based on fixed-effect meta-analysis |
est.repl |
effect size estimate of replication |
se.repl |
standard error of replication's effect size estimate |
ci.lb.repl |
lower bound of replication's confidence interval |
ci.ub.repl |
upper bound of replication's confidence interval |
stat.repl |
test statistic of replication for testing null-hypothesis of no effect |
pval.repl |
two-tailed p-value of replication for testing null-hypothesis of no effect |
The control
argument in the hybrid
function is an optional
argument that gives the user more control over the estimation procedures.
This can be especially useful if estimation of the method does not converge
and NAs are returned by the function. The control
argument should
be specified as a list containing one or more elements. For example,
control = list(verbose = TRUE)
Default values are used if an element is
not specified. The following elements can be specified by the user:
int:
A vector of length two that indicates the lower and upper
bound of the interval that is used for estimating the effect size. The effect
size estimate should be included in this interval. Its default values are -10
for the first element and the maximum effect size of a study included in the
analysis + 1 as the second element. This control argument is only applicable
to the implementation of van Aert and van Assen (2018).
est.ci:
A vector of length two indicating the values that are
subtracted from and added to the estimate of the effect size for computing the
95% confidence intervals. Its default values are (50, 1). To give an example,
estimates for the lower and upper bound around the effect size estimate are
searched on the interval (est-50, est) and (est, est+1), respectively.
tau2.ci
A vector of length two indicating the values that are
subtracted from and added to the estimate of the between-study variance for
computing the 95% confidence intervals. Its default values are (0.5, 0.5).
To give an example, estimates for the lower and upper bound around the effect
size estimate are searched on the interval (tau2-0.5, tau2) and (tau2, tau2+0.5),
respectively.
tol:
A number indicating the desired accuracy of the estimates.
Its default value is .Machine$double.eps^0.25. This control argument is only
applicable to the implementation of van Aert and van Assen (2018).
verbose:
A logical indicating whether information should be printed
about the estimation procedure. Its default value is FALSE.
par:
Starting values for the optimization procedure in case of
the implementation of van Aert (2023). The default values are zeros.
implementation:
A character indicating whether the implementation
of van Aert and van Assen (2018) based on a single conventional and single replication
should be used (implementation = "two"
) or whether the implementation
of van Aert (2023) should be used that allows for including more than two studies
(implementation = "multiple"
).
optimizer:
A character indicating the optimizer that is used if
the implementation of van Aert (2023) is used. The default value is "Nelder-Mead".
The optim
function is used for optimization, so the optimization
methods implemented in the optim
function can be used. See the
documentation of the optim
function for more information.
type:
A character vector indicating whether Wald-based hypothesis
tests and confidence intervals are preferred (type = "Wald"
) or
likelihood-ratio tests and profile likelihood confidence intervals
(type = "profile"
). The default is "Wald/profile" which implies that
Wald tests and confidence intervals are computed for the fixed effects and
likelihood-ratio tests and profile likelihood confidence intervals for the
between-study variance.
Robbie C.M. van Aert [email protected]
van Aert, R. C. M., & van Assen, M. A. L. M. (2018). Examining reproducibility in psychology: A hybrid method for statistically combining a biased original study and replication. Behavior Research Methods, 50(4): 1515-1539. doi:10.3758/s13428-017-0967-6
van Aert, R.C.M. (2023). Empowering meta-analysis by taking advantage of preregistered studies: The extended hybrid meta-analysis method. Manuscript in preparation.
### Application using the implementation of van Aert (2023) with more than two studies. # Note that these data come from the "metadat" R package that needs to be loaded. # The data come from the meta-analyses by Lehmann et al. (2018). See the help # file of dat.lehmann2018 for more information about this meta-analysis. library(metadat) dat <- dat.lehmann2018 ### Create a new object to indicate which studies were conventional studies and # which ones were preregistered dat$conventional <- ifelse(dat$Preregistered == "Not Pre-Registered", 1, 0) ### Lehmann et al. split the analyses for males and females. We only use the data # of females for this example. red_romance_femalep <- dat[dat$Gender == "Females", ] ### Prepare data for the analysis yi <- red_romance_femalep$yi vi <- red_romance_femalep$vi conventional <- red_romance_femalep$conventional ### Apply the hybrid method with Wald-type hypothesis tests and confidence intervals hybrid(yi = yi, vi = vi, conventional = conventional, side = "right") ### Apply the hybrid method with likelihood ratio hypothesis tests and profile # likelihood confidence intervals hybrid(yi = yi, vi = vi, conventional = conventional, side = "right", control = list(type = "profile")) ### Include Color_Match as moderator Color_Match <- red_romance_femalep$Color_Match ### Apply the hybrid method with Wald-type hypothesis tests and confidence intervals hybrid(yi = yi, vi = vi, conventional = conventional, side = "right", mods = ~ Color_Match) ### Apply the hybrid method with likelihood ratio hypothesis tests and profile # likelihood confidence intervals hybrid(yi = yi, vi = vi, conventional = conventional, side = "right", mods = ~ Color_Match, control = list(type = "profile")) ### Application using the implementation of van Aert and van Assen (2018). # The hybrid method is applied to example on page 5 of van Aert and van Assen # (2018). pval <- c(0.03, 0.3) # p-value conventional study and replication n1i <- n2i <- c(40, 80) # Sample sizes per group tobs <- qt(pval/2, df = n1i+n2i-2, lower.tail = FALSE) # Observed t-values ### Apply hybrid method using the implementation of van Aert and van Assen (2018) hybrid(tobs = tobs, n1i = n1i, n2i = n2i, side = "right", conventional = c(1,0), control = list(implementation = "two"))
### Application using the implementation of van Aert (2023) with more than two studies. # Note that these data come from the "metadat" R package that needs to be loaded. # The data come from the meta-analyses by Lehmann et al. (2018). See the help # file of dat.lehmann2018 for more information about this meta-analysis. library(metadat) dat <- dat.lehmann2018 ### Create a new object to indicate which studies were conventional studies and # which ones were preregistered dat$conventional <- ifelse(dat$Preregistered == "Not Pre-Registered", 1, 0) ### Lehmann et al. split the analyses for males and females. We only use the data # of females for this example. red_romance_femalep <- dat[dat$Gender == "Females", ] ### Prepare data for the analysis yi <- red_romance_femalep$yi vi <- red_romance_femalep$vi conventional <- red_romance_femalep$conventional ### Apply the hybrid method with Wald-type hypothesis tests and confidence intervals hybrid(yi = yi, vi = vi, conventional = conventional, side = "right") ### Apply the hybrid method with likelihood ratio hypothesis tests and profile # likelihood confidence intervals hybrid(yi = yi, vi = vi, conventional = conventional, side = "right", control = list(type = "profile")) ### Include Color_Match as moderator Color_Match <- red_romance_femalep$Color_Match ### Apply the hybrid method with Wald-type hypothesis tests and confidence intervals hybrid(yi = yi, vi = vi, conventional = conventional, side = "right", mods = ~ Color_Match) ### Apply the hybrid method with likelihood ratio hypothesis tests and profile # likelihood confidence intervals hybrid(yi = yi, vi = vi, conventional = conventional, side = "right", mods = ~ Color_Match, control = list(type = "profile")) ### Application using the implementation of van Aert and van Assen (2018). # The hybrid method is applied to example on page 5 of van Aert and van Assen # (2018). pval <- c(0.03, 0.3) # p-value conventional study and replication n1i <- n2i <- c(40, 80) # Sample sizes per group tobs <- qt(pval/2, df = n1i+n2i-2, lower.tail = FALSE) # Observed t-values ### Apply hybrid method using the implementation of van Aert and van Assen (2018) hybrid(tobs = tobs, n1i = n1i, n2i = n2i, side = "right", conventional = c(1,0), control = list(implementation = "two"))
Function to create meta-plots for two-independent means, raw correlations, and odds ratios. See van Assen et al. (2023) for more information.
meta_plot( m1i, m2i, sd1i, sd2i, n1i, n2i, gi, vgi, ri, ni, ai, bi, ci, di, alpha = 0.05, method_tau2 = "PM", nr_lines = "all", pub_bias = TRUE, main = "", cex.pch = 1 )
meta_plot( m1i, m2i, sd1i, sd2i, n1i, n2i, gi, vgi, ri, ni, ai, bi, ci, di, alpha = 0.05, method_tau2 = "PM", nr_lines = "all", pub_bias = TRUE, main = "", cex.pch = 1 )
m1i |
A vector of means in group 1 for two-independent means |
m2i |
A vector of means in group 2 for two-independent means |
sd1i |
A vector of standard deviations in group 1 for two-independent means |
sd2i |
A vector of standard deviations in group 2 for two-independent means |
n1i |
A vector of sample sizes in group 1 for two-independent means |
n2i |
A vector of sample sizes in group 2 for two-independent means |
gi |
A vector of Hedges' g values for two-independent means if group means and standard deviations are not available |
vgi |
A vector of Hedges' g sampling variances for two-independent means if group means and standard deviations are not available |
ri |
A vector of raw correlations |
ni |
A vector of sample sizes if raw correlations are the effect size measure |
ai |
A vector of frequencies in upper left cell of 2x2 frequency table (see Details) |
bi |
A vector of frequencies in upper right cell of 2x2 frequency table (see Details) |
ci |
A vector of frequencies in lower left cell of 2x2 frequency table (see Details) |
di |
A vector of frequencies in lower right cell of 2x2 frequency table (see Details) |
alpha |
A numerical value specifying the alpha level as used in primary studies (default is 0.05 but see Details) |
method_tau2 |
A character indicating the estimation method for the
between-study variance in true effect size in the meta-analysis
(default is |
nr_lines |
A character indicating whether all primary study's effect sizes
( |
pub_bias |
A logical indicating whether the expected results of the cumulative meta-analysis based on a zero true effect in combination with extreme publication bias should be plotted. The default value is NA implying that these results are only included if at least 80% of the primary studies is statistically significant. These results are always included if this argument is set to TRUE and never included if this argument is set to FALSE |
main |
A character indicating the title of the plot (default is no title) |
cex.pch |
A numerical value to control the size of the points in the plot |
The meta_plot
function assumes that two-tailed hypothesis tests
were conducted in the primary studies. In case one-tailed hypothesis tests were
conducted in the primary studies, the submitted alpha
argument to the
meta_plot
function has to be multiplied by two. For example, if one-tailed
hypothesis tests were conducted with an alpha level of .05, an alpha of 0.1
has to be submitted to the meta_plot
function.
Different estimators can be used for estimating the between-study variance in
true effect size. The default estimator is the Paule-Mandel estimator
(Paule & Mandel, 1982), because this estimator was recommended in Veroniki
et al. (2016) and Langan, Higgins, and Simmonds (2016). However, all estimators
that are included in the rma.uni
function of the metafor
package
can be used, because this function is called in the meta_plot
function.
When nr_lines = "summary"
is specified, the estimates of meta-analyses
based on primary studies with sufficient statistical power are displayed.
Next to the estimate and 95% confidence interval of the meta-analysis including
all studies (leftmost), it shows these results for studies with sufficient
statistical power (80%) to detect a large true effect size (left vertical line),
medium true effect size (middle), and small true effect size (right). Note
that the summary meta-plot is just the meta-plot with many meta-analyses and
confidence intervals left out, and keeping the leftmost meta-analysis and
those just immediately to the right of the vertical lines.
The meta-plot can be created for standardized mean differences by providing
the function with the sample means (m1i
and m21
), the sample
sizes (n1i
and n2i
), and the standard deviations (sd1i
and
sd2i
) or by specifying the standardized mean differences (i.e., Hedges'
g; gi
) together with the corresponding sampling variances (vgi
)
and the sample sizes (n1i
and n2i
). Hedges' g standardized
mean differences and corresponding sampling variances are computed in the
function if the sample means, sample sizes, and standard deviations are provided.
For creating a meta-plot based on odds ratios as effect size measure, the 2x2 frequency table should follow a specific format. The reason for this is that the probability for the outcome of interest in the control conditions has to be estimated. Hence, the 2x2 frequency table should look like this:
Outcome 1 | Outcome 2 | |
Group 1 | ai | bi |
Group 2 | ci | di |
An invisibly returned data frame consisting of the submitted data and
yi |
Standardized effect sizes used in the analyses |
vi |
Sampling variances of the standardized effect sizes used in the analyses |
est_cum |
Estimates of the cumulative meta-analyses |
lb_cum |
Lower bounds of the 95% confidence intervals of the cumulative meta-analyses |
ub_cum |
Upper bounds of the 95% confidence intervals of the cumulative meta-analyses |
pub_est |
Estimates of cumulative meta-analyses based on Mill's ratios |
info |
Information of a primary study (only for two-independent means) |
stand_info |
Standardized information of a primary study (only for two-independent means) |
preci |
Precision of a primary study (only for odds ratios) |
Robbie C.M. van Aert [email protected]
Langan, D., Higgins, J. P. T., & Simmonds, M. (2016). Comparative performance of heterogeneity variance estimators in meta-analysis: A review of simulation studies. Research Synthesis Methods, 8(2), 181-198. doi:10.1002/jrsm.1198
Paule, R. C., & Mandel, J. (1982). Consensus values and weighting factors. Journal of Research of the National Bureau of Standards, 87(5), 377-385.
van Assen, ..., & van Aert (2023). The meta-plot: A graphical tool for interpreting the results of a meta-analysis. Zeitschrift fur Psychologie, 231(1), 65-78. doi:10.1027/2151-2604/a000513
Veroniki, A. A., Jackson, D., Viechtbauer, W., Bender, R., Bowden, J., Knapp, G., . . . Salanti, G. (2016). Methods to estimate the between-study variance and its uncertainty in meta-analysis. Research Synthesis Methods, 7(1), 55-79. doi:10.1002/jrsm.1164
### Load data from meta-analysis by McCall and Carriger (1993) data(data.mccall93) ### Create meta-plot meta_plot(ri = data.mccall93$ri, ni = data.mccall93$ni) ### Create summary meta-plot meta_plot(ri = data.mccall93$ri, ni = data.mccall93$ni, nr_lines = "summary")
### Load data from meta-analysis by McCall and Carriger (1993) data(data.mccall93) ### Create meta-plot meta_plot(ri = data.mccall93$ri, ni = data.mccall93$ni) ### Create summary meta-plot meta_plot(ri = data.mccall93$ri, ni = data.mccall93$ni, nr_lines = "summary")
Function to apply the p-uniform* method for one-sample mean, two-independent means, and one raw correlation coefficient as described in van Aert and van Assen (2023).
puni_star( mi, ri, ni, sdi, m1i, m2i, n1i, n2i, sd1i, sd2i, tobs, yi, vi, alpha = 0.05, side, method = "ML", boot = FALSE, control )
puni_star( mi, ri, ni, sdi, m1i, m2i, n1i, n2i, sd1i, sd2i, tobs, yi, vi, alpha = 0.05, side, method = "ML", boot = FALSE, control )
mi |
A vector of group means for one-sample means |
ri |
A vector of raw correlations |
ni |
A vector of sample sizes for one-sample means and correlations |
sdi |
A vector of standard deviations for one-sample means |
m1i |
A vector of means in group 1 for two-independent means |
m2i |
A vector of means in group 2 for two-independent means |
n1i |
A vector of sample sizes in group 1 for two-independent means |
n2i |
A vector of sample sizes in group 2 for two-independent means |
sd1i |
A vector of standard deviations in group 1 for two-independent means |
sd2i |
A vector of standard deviations in group 2 for two-independent means |
tobs |
A vector of t-values |
yi |
A vector of standardized effect sizes (see Details) |
vi |
A vector of sampling variances belonging to the standardized effect sizes (see Details) |
alpha |
A numerical value specifying the alpha level as used in primary studies (default is 0.05 but see Details). |
side |
A character indicating whether the effect sizes in the primary studies
are in the right-tail of the distribution (i.e., positive) or in the left-tail
of the distribution (i.e., negative) (either |
method |
A character indicating the method to be used |
boot |
A logical indicating whether the p-value of testing whether the
between-study variance is zero for methods |
control |
An optional list of elements that give the user more control over the optimization and root-finding algorithms (see Note) |
Three different effect size measures can be used as input for the puni_star
function: one-sample means, two-independent means, and raw correlation coefficients.
Analyzing one-sample means and two-independent means can be done by either providing
the function group means (mi
or m1i
and m2i
), standard deviations
(sdi
or sd1i
and sd2i
), and sample sizes (ni
or
n1i
and n2i
) or t-values (tobs
) and sample sizes (ni
or n1i
and n2i
). Both options should be accompanied with input
for the arguments side
, method
, and alpha
. See the Example section for
examples. Raw correlation coefficients can be analyzed by supplying the raw
correlation coefficients ri
and sample sizes and ni
to the
puni_star
function next to input for the arguments side
,
method
, and alpha
. Note that the method internally transforms the
raw correlation coefficients to Fisher's z correlation coefficients. The output
of the function also shows the results for the Fisher's z correlation coefficient.
Hence, the results need to be transformed to raw correlation coefficients if
this is preferred by the user.
It is also possible to specify the standardized effect sizes and its sampling
variances directly via the yi
and vi
arguments. However, extensive
knowledge about computing standardized effect sizes and its sampling variances
is required and specifying standardized effect sizes and sampling variances is
not recommended to be used if the p-values in the primary studies are not computed
with a z-test. In case the p-values in the primary studies were computed with,
for instance, a t-test, the p-values of a z-test and t-test do not exactly
coincide and studies may be incorrectly included as a statistically significant or
nonsignificant effect size. Furthermore, critical values in the primary studies
are not transformed to critical z-values if yi
and vi
are used
as input. This yields less accurate results.
The puni_star
function assumes that two-tailed hypothesis tests were conducted
in the primary studies. In case one-tailed hypothesis tests were conducted in
the primary studies, the submitted alpha
argument to the puni_star
function has to be multiplied by two. For example, if one-tailed hypothesis tests were
conducted with an alpha level of .05, an alpha of 0.1 has to be submitted to
the puni_star
function.
Note that only one effect size measure can be specified at a time. A combination of effect size measures usually causes true heterogeneity among effect sizes and including different effect size measures is therefore not recommended.
Selecting a method
Three different methods are currently implemented in the puni_star
function.
The ML
method refers to maximum likelihood estimation of the effect size
and the between-study variance. Profile likelihood confidence intervals around
the estimates are computed by means of inverting the likelihood-ratio test.
Likelihood-ratio tests are used for testing the null hypotheses of no effect
and no between-study variance. The ML
method is the recommended method
for applying p-uniform*.
The two other methods (P
and LNP
) are moment based estimators.
The method P
is based on the distribution of the sum of independent
uniformly distributed random variables (Irwin-Hall distribution) and the
LNP
method refers to Fisher's method (1950, Chapter 4). For these methods,
a p-value for testing the null hypothesis of no between-study variance can also be
obtained by means of a parametric bootstrap. This is necessary since the data
is otherwise first used for estimating the effect size in the procedure for testing
the null hypothesis of no between-study variance and then also used for computing
a p-value. The test of no effect is not available for the methods P
and LNP
and the publication bias test for these methods is not yet implemented.
est |
p-uniform*'s effect size estimate |
ci.lb |
lower bound of p-uniform*'s 95% confidence interval of the effect size |
ci.ub |
upper bound of p-uniform*'s 95% confidence interval of the effect size |
L.0 |
test statistic of p-uniform*'s test of the null hypothesis of no effect |
pval.0 |
one-tailed p-value of p-uniform*'s test of null hypothesis of no effect |
tau2 |
p-uniform*'s estimate of the between-study variance |
tau2.lb |
lower bound of p-uniform*'s 95% confidence interval of the between-study variance |
tau2.ub |
upper bound of p-uniform*'s 95% confidence interval of the between-study variance |
L.het |
test statistic of p-uniform*'s test of the null hypothesis of no between-study variance |
pval.het |
one-tailed p-value of p-uniform*'s test of null hypothesis of no between-study variance |
pval.boot |
one-tailed p-value of p-uniform*'s test of null hypothesis of no between-study variance obtained with a parametric bootstrap |
... |
a number of additional elements |
The control
argument in the puni_star
function is an optional
argument that gives the user more control over the optimization and root-finding
algorithms. This can be especially useful if estimation of the method does not
converge and NAs are returned by the function. The control
argument should
be specified as a list containing one or more elements. For example,
control = list(verbose = TRUE)
Default values are used if an element is
not specified. The following elements can be specified by the user:
proc.ml:
A character indicating with optimization procedure should
be used for the method ML
. The initial implementation of p-uniform* iteratively
optimized the profile log-likelihood functions. As of version 0.2.6 of this
package, the default optimization routine estimates both parameters at the
same time. The old optimization procedure can be used by specifying proc.ml = "prof"
.
stval.d:
An integer that is the starting value of the effect
size for estimation. This starting value is used for the method ML
and
is only needed when both parameters are estimated at the same time. See argument
proc.ml
for more information. The default value is the mean of the effect
sizes in the meta-analysis.
stval.tau:
An integer that is the starting value of tau for estimation.
This starting value is used for the methods ML
, P
, and LNP
.
The default value is the standard deviation of the effect sizes in the meta-analysis.
int:
A vector of length two that indicates the lower and upper
bound of the interval that is used for estimating the effect size. The effect
size estimate should be included in this interval. This interval is used for the
methods ML
, P
, and LNP
and its default values are (-2, 2).
bounds.int
A vector of length two that is used for determining the
bounds for estimating the effect size with P
and LNP
. The default
values are a function of the yi
. The lower bound is the minimum yi
minus 1 and the upper bound is the maximum yi
plus 1. The effect size
has to be between the lower and upper bound.
tau.int:
A vector of length two that indicates the lower and upper
bound of the interval that is used for estimating the between-study variance.
The estimate of the between-study variance should be included in this interval.
This interval is used for the methods ML
, P
, and LNP
and its default values are (0, 2).
est.ci:
A vector of length two indicating the values that are
subtracted from and added to the estimate of the effect size for computing the
95% confidence intervals. This vector is used for the methods ML
,
P
, and LNP
and its default values are (3, 3). To give an example,
estimates for the lower and upper bound around the effect size estimate are
searched on the interval (est-3, est) and (est, est+3), respectively.
tau.ci:
A vector of length two indicating the values that are
added to the estimate of the between-study variance for computing the 95% confidence
intervals. This vector is used for the methods ML
, P
, and LNP
and its default values are (3, 1).
tol:
A number indicating the desired accuracy of the estimates.
This number is used for the methods ML
, P
, and LNP
and its
default value is 0.001.
maxit:
An integer indicating the maximum number of iterations
that is used for estimating the effect size and between-study variance. This
number is used for the methods ML
, P
, and LNP
and its default
value is 300.
fnscale:
An integer that can be used for scaling the log-likelihood
value in the optimization. fnscale
is one of the control arguments of
the optim()
function that is internally used for optimization when the
ML
method is used and both parameters are estimated at the same time.
See the argument proc.ml
above #' and the documentation of the optim()
function for more information.
verbose:
A logical indicating whether information should be printed
about the algorithm for estimating the effect size and between-study variance.
This logical is used for the methods ML
, P
, and LNP
and
its default value is FALSE.
reps:
An integer indicating the number of bootstrap replications
for computing the bootstrapped p-value for the test of no between-study variance.
This integer is used for the methods P
and LNP
and its default value
is 1000.
Robbie C.M. van Aert [email protected]
Fisher, R.A. (1950). Statistical methods for research workers (11th ed.). London: Oliver & Boyd.
van Aert, R.C.M., & van Assen, M.A.L.M. (2023). Correcting for publication bias in a meta-analysis with the p-uniform* method. Manuscript submitted for publication. Preprint: https://osf.io/preprints/bitss/zqjr9/
### Generate data for one-sample mean with mu = 0.2 and tau^2 = 0.01 set.seed(123) ni <- rep(50, 25) sdi <- rep(1, 25) ui <- rnorm(25, mean = 0.2, sd = 0.1) mi <- rnorm(25, mean = ui, sd = sdi/sqrt(ni)) tobs <- mi/(sdi/sqrt(ni)) ### Apply p-uniform* method using sample means puni_star(mi = mi, ni = ni, sdi = sdi, alpha = 0.05, side = "right", method = "ML") ### Apply p-uniform* method using t-values puni_star(tobs = tobs, ni = ni, alpha = 0.05, side = "right", method = "ML")
### Generate data for one-sample mean with mu = 0.2 and tau^2 = 0.01 set.seed(123) ni <- rep(50, 25) sdi <- rep(1, 25) ui <- rnorm(25, mean = 0.2, sd = 0.1) mi <- rnorm(25, mean = ui, sd = sdi/sqrt(ni)) tobs <- mi/(sdi/sqrt(ni)) ### Apply p-uniform* method using sample means puni_star(mi = mi, ni = ni, sdi = sdi, alpha = 0.05, side = "right", method = "ML") ### Apply p-uniform* method using t-values puni_star(tobs = tobs, ni = ni, alpha = 0.05, side = "right", method = "ML")
Function to apply the p-uniform method for one-sample mean, two-independent means, and one raw correlation coefficient as described in van Assen, van Aert, and Wicherts (2015) and van Aert, Wicherts, and van Assen (2016).
puniform( mi, ri, ni, sdi, m1i, m2i, n1i, n2i, sd1i, sd2i, tobs, yi, vi, alpha = 0.05, side, method = "P", plot = FALSE )
puniform( mi, ri, ni, sdi, m1i, m2i, n1i, n2i, sd1i, sd2i, tobs, yi, vi, alpha = 0.05, side, method = "P", plot = FALSE )
mi |
A vector of group means for one-sample means |
ri |
A vector of raw correlations |
ni |
A vector of sample sizes for one-sample means and correlations |
sdi |
A vector of standard deviations for one-sample means |
m1i |
A vector of means in group 1 for two-independent means |
m2i |
A vector of means in group 2 for two-independent means |
n1i |
A vector of sample sizes in group 1 for two-independent means |
n2i |
A vector of sample sizes in group 2 for two-independent means |
sd1i |
A vector of standard deviations in group 1 for two-independent means |
sd2i |
A vector of standard deviations in group 2 for two-independent means |
tobs |
A vector of t-values |
yi |
A vector of standardized effect sizes (see Details) |
vi |
A vector of sampling variances belonging to the standardized effect sizes (see Details) |
alpha |
A numerical value specifying the alpha level as used in primary studies (default is 0.05, see Details). |
side |
A character indicating whether the effect sizes in the primary studies
are in the right-tail of the distribution (i.e., positive) or in the left-tail
of the distribution (i.e., negative) (either |
method |
A character indicating the method to be used |
plot |
A logical indicating whether a plot showing the relation between
observed and expected p-values has to be rendered (default is |
Three different effect size measures can be used as input for the puniform
function: one-sample means, two-independent means, and raw correlation coefficients.
Analyzing one-sample means and two-independent means can be done by either providing
the function group means (mi
or m1i
and m2i
), standard deviations
(sdi
or sd1i
and sd2i
), and sample sizes (ni
or
n1i
and n2i
) or t-values (tobs
) and sample sizes (ni
or n1i
and n2i
). Both options should be accompanied with input
for the arguments side
, method
, and alpha
. See the Example section for
examples. Raw correlation coefficients can be analyzed by supplying the raw
correlation coefficients ri
and sample sizes and ni
to the
puni_star
function next to input for the arguments side
,
method
, and alpha
. Note that the method internally transforms the
raw correlation coefficients to Fisher's z correlation coefficients. The output
of the function also shows the results for the Fisher's z correlation coefficient.
Hence, the results need to be transformed to raw correlation coefficients if
this is preferred by the user.
It is also possible to specify the standardized effect sizes and its sampling
variances directly via the yi
and vi
arguments. However, extensive
knowledge about computing standardized effect sizes and its sampling variances
is required and specifying standardized effect sizes and sampling variances is
not recommended to be used if the p-values in the primary studies are not computed
with a z-test. In case the p-values in the primary studies were computed with,
for instance, a t-test, the p-values of a z-test and t-test do not exactly
coincide and studies may be incorrectly included in the analyses. Furthermore,
critical values in the primary studies cannot be transformed to critical z-values
if yi
and vi
are used as input. This yields less accurate results.
The puniform
function assumes that two-tailed hypothesis tests were conducted
in the primary studies. In case one-tailed hypothesis tests were conducted in the primary studies,
the alpha level has to be multiplied by two. For example, if one-tailed hypothesis
tests were conducted with an alpha level of .05, an alpha of 0.1 has to be
submitted to p-uniform.
Note that only one effect size measure can be specified at a time. A combination of effect size measures usually causes true heterogeneity among effect sizes and including different effect size measures is therefore not recommended.
Six different estimators can be used when applying p-uniform. The P
method
is based on the distribution of the sum of independent uniformly distributed random
variables (Irwin-Hall distribution) and is the recommended estimator (van Aert et al., 2016).
The ML
estimator refers to effect size estimation with maximum likelihood.
Profile likelihood confidence intervals are computed, and likelihood ratio tests are
used for the test of no effect and publication bias test if ML
is used.
The LNP
estimator refers to Fisher's method (1950, Chapter 4)
for combining p-values and the LN1MINP
estimator first computes 1 - p-value in each
study before applying Fisher's method on these transformed p-values
(van Assen et al., 2015). KS
and AD
respectively use the Kolmogorov-Smirnov
test (Massey, 1951) and the Anderson-Darling test (Anderson & Darling, 1954)
for testing whether the (conditional) p-values follow a uniform distribution.
est |
p-uniform's effect size estimate |
ci.lb |
lower bound of p-uniform's confidence interval |
ci.ub |
upper bound of p-uniform's confidence interval |
ksig |
number of significant studies |
L.0 |
test statistic of p-uniform's test of null-hypothesis of no effect
(for method |
pval.0 |
one-tailed p-value of p-uniform's test of null-hypothesis of no effect |
L.pb |
test statistic of p-uniform's publication bias test |
pval.pb |
one-tailed p-value of p-uniform's publication bias test |
est.fe |
effect size estimate based on traditional fixed-effect meta-analysis |
se.fe |
standard error of effect size estimate based on traditional fixed-effect meta-analysis |
zval.fe |
test statistic of the null-hypothesis of no effect based on traditional fixed-effect meta-analysis |
pval.fe |
one-tailed p-value of the null-hypothesis of no effect based on traditional fixed-effect meta-analysis |
ci.lb.fe |
lower bound of confidence interval based on traditional fixed-effect meta-analysis |
ci.ub.fe |
ci.ub.fe upper bound of confidence interval based on traditional fixed-effect meta-analysis |
Qstat |
test statistic of the Q-test for testing the null-hypothesis of homogeneity |
Qpval |
one-tailed p-value of the Q-test |
Robbie C.M. van Aert [email protected]
Anderson, T. W., & Darling, D. A. (1954). A test of goodness of fit. Journal of the American Statistical Association, 49(268), 765-769.
Fisher, R. A. (1950). Statistical methods for research workers (11th ed.). London: Oliver & Boyd.
Massey, F. J. (1951). The Kolmogorov-Smirnov test for goodness of fit. Journal of the American Statistical Association, 46(253), 68-78.
Van Aert, R. C. M., Wicherts, J. M., & van Assen, M. A. L. M. (2016). Conducting meta-analyses on p-values: Reservations and recommendations for applying p-uniform and p-curve. Perspectives on Psychological Science, 11(5), 713-729. doi:10.1177/1745691616650874
Van Assen, M. A. L. M., van Aert, R. C. M., & Wicherts, J. M. (2015). Meta-analysis using effect size distributions of only statistically significant studies. Psychological Methods, 20(3), 293-309. doi: http://dx.doi.org/10.1037/met0000025
### Load data from meta-analysis by McCall and Carriger (1993) data(data.mccall93) ### Apply p-uniform method puniform(ri = data.mccall93$ri, ni = data.mccall93$ni, side = "right", method = "LNP", plot = TRUE) ### Generate example data for one-sample means design set.seed(123) ni <- 100 sdi <- 1 mi <- rnorm(8, mean = 0.2, sd = sdi/sqrt(ni)) tobs <- mi/(sdi/sqrt(ni)) ### Apply p-uniform method based on sample means puniform(mi = mi, ni = ni, sdi = sdi, side = "right", plot = FALSE) ### Apply p-uniform method based on t-values puniform(ni = ni, tobs = tobs, side = "right", plot = FALSE)
### Load data from meta-analysis by McCall and Carriger (1993) data(data.mccall93) ### Apply p-uniform method puniform(ri = data.mccall93$ri, ni = data.mccall93$ni, side = "right", method = "LNP", plot = TRUE) ### Generate example data for one-sample means design set.seed(123) ni <- 100 sdi <- 1 mi <- rnorm(8, mean = 0.2, sd = sdi/sqrt(ni)) tobs <- mi/(sdi/sqrt(ni)) ### Apply p-uniform method based on sample means puniform(mi = mi, ni = ni, sdi = sdi, side = "right", plot = FALSE) ### Apply p-uniform method based on t-values puniform(ni = ni, tobs = tobs, side = "right", plot = FALSE)
Function for computing the required sample size for a replication based on the Snapshot Bayesian Hybrid Meta-Analysis Method for two-independent means and raw correlation coefficients.
req_ni_r( ri.o, ni.o, m1i.o, m2i.o, n1i.o, n2i.o, sd1i.o, sd2i.o, tobs.o, alpha, des.pprob, des.pow, lo = 4, hi = 1e+05 )
req_ni_r( ri.o, ni.o, m1i.o, m2i.o, n1i.o, n2i.o, sd1i.o, sd2i.o, tobs.o, alpha, des.pprob, des.pow, lo = 4, hi = 1e+05 )
ri.o |
A numeric value containing the raw correlation coefficient of the original study |
ni.o |
An integer containing the sample size for the raw correlation coefficient |
m1i.o |
A numeric value containing the mean in group 1 of the original study for two-independent means |
m2i.o |
A numeric value containing the mean in group 2 of the original study for two-independent means |
n1i.o |
A numeric value containing the sample size in group 1 of the original study for two-independent means |
n2i.o |
A numeric value containing the sample size in group 2 of the original study for two-independent means |
sd1i.o |
A numeric value containing the standard deviation in group 1 of the original study for two-independent means |
sd2i.o |
A numeric value containing the standard deviation in group 2 of the original study for two-independent means |
tobs.o |
A numeric value containing the t-value of the original study |
alpha |
A numeric value specifying the alpha level as used in the original study |
des.pprob |
A numeric value specifying the posterior probability that an user desires to obtain for one of the four true effect sizes |
des.pow |
A numeric value specifying the probability of observing a posterior probability larger than des.pprob that an user desires to obtain for one of the four true effect sizes |
lo |
A numeric value specifying the lower bound of the search interval that is used for the optimization procedure (default is 4) |
hi |
A numeric value specifying the upper bound of the search interval that is used for the optimization procedure (default is 100,000) |
The function computes the required sample size for the replication based
on the Snapshot Bayesian Hybrid Meta-Analysis Method for four true effect sizes
(no, small, medium, and large). The required sample size is computed by optimizing
with
being the posterior probability with x
referring to no (0), small (S), medium (M), and large (L) true effect size and
the desired posterior probability, and
the desired probability of observing
a posterior probability larger than
. The required sample size for the
replication is computed with and without including information of the original
study. Computing the required sample size with the Snapshot Bayesian Hybrid
Meta-Analysis Method is akin to computing the required sample size with a power
analysis in null hypothesis significance testing. For more information see van
Aert and van Assen (2016).
The req.ni.r
function assumes that a two-tailed hypothesis test was
conducted in the original study. In case one-tailed hypothesis tests was
conducted in the original study, the alpha level has to be multiplied by two.
For example, if a one-tailed hypothesis test was conducted with an alpha level
of .05, an alpha of 0.1 has to be submitted to req.ni.r
.
The req.ni.r
function returns a 4x2 matrix with in the first
column the required total sample size of the replication when information of the
original study is taken into account and in the second column the required sample
size if information of the original study is ignored.
Robbie C.M. van Aert [email protected]
van Aert, R.C.M. & van Assen, M.A.L.M. (2016). Bayesian evaluation of effect size after replicating an original study. Manuscript submitted for publication.
### Example as presented on page 491 in Maxwell, Lau, and Howard (2015) req_ni_r(ri.o = 0.243, ni.o = 80, alpha = .05, des.pprob = 0.75, des.pow = 0.8)
### Example as presented on page 491 in Maxwell, Lau, and Howard (2015) req_ni_r(ri.o = 0.243, ni.o = 80, alpha = .05, des.pprob = 0.75, des.pow = 0.8)
Function for applying Snapshot Bayesian Hybrid Meta-Analysis Method for two-independent means and raw correlation coefficients.
snapshot(ri, ni, m1i, m2i, n1i, n2i, sd1i, sd2i, tobs, alpha = 0.05)
snapshot(ri, ni, m1i, m2i, n1i, n2i, sd1i, sd2i, tobs, alpha = 0.05)
ri |
A vector of length two containing the raw correlation coefficients of the original study and replication |
ni |
A vector of length two containing the sample size of the original study and replication for the raw correlation coefficient |
m1i |
A vector of length two containing the means in group 1 for the original study and replication for two-independent means |
m2i |
A vector of length two containing the means in group 2 for the original and replication for two-independent means |
n1i |
A vector of length two containing the sample sizes in group 1 for the original study and replication for two-independent means |
n2i |
A vector of length two containing the sample sizes in group 2 for the original study and replication for two-independent means |
sd1i |
A vector of length two containing the standard deviations in group 1 for the original study and replication for two-independent means |
sd2i |
A vector of length two containing the standard deviations in group 2 for the original study and replication for two-independent means |
tobs |
A vector of length two containing the t-values of the original study and replication |
alpha |
A numerical value specifying the alpha level as used in the original study (default is 0.05, see Details) |
The function computes posterior probabilities (assuming a uniform prior distribution) for four true effect sizes (no, small, medium, and large) based on an original study and replication while taking into account statistical significance in the original study. For more information see van Aert and van Assen (2016).
Two different effect size measures can be used as input for the snapshot
function: two-independent means and raw correlation coefficients.
Analyzing two-independent means can be done by either providing
the function group means (m1i
and m2i
), standard deviations
(sd1i
and sd2i
), and sample sizes (n1i
and n2i
) or
t-values (tobs
) and sample sizes (n1i
and n2i
). Both options
should be accompanied with input for the argument alpha
. See the Example section for
an example. Raw correlation coefficients can be analyzed by supplying ri
and ni
to the snapshot
function next to input for the argument
alpha
.
The snapshot
function assumes that a two-tailed hypothesis test was
conducted in the original study. In case a one-tailed hypothesis test was
conducted in the original study, the alpha level has to be multiplied by two.
For example, if a one-tailed hypothesis test was conducted with an alpha level
of .05, an alpha of 0.1 has to be submitted to snapshot
.
The snapshot
function returns a data frame with posterior probabilities
for no (p.0
), small (p.sm
), medium (p.me
), and large (p.la
)
true effect size.
Robbie C.M. van Aert [email protected]
van Aert, R.C.M. & van Assen, M.A.L.M. (2017). Bayesian evaluation of effect size after replicating an original study. PLoS ONE, 12(4), e0175302. doi:10.1371/journal.pone.0175302
### Example as presented on page 491 in Maxwell, Lau, and Howard (2015) snapshot(ri = c(0.243, 0.114), ni = c(80, 172))
### Example as presented on page 491 in Maxwell, Lau, and Howard (2015) snapshot(ri = c(0.243, 0.114), ni = c(80, 172))
Function for applying Snapshot Bayesian Meta-Analysis Method (snapshot naive) for two-independent means and raw correlation coefficients.
snapshot_naive(ri, ni, m1i, m2i, n1i, n2i, sd1i, sd2i, tobs)
snapshot_naive(ri, ni, m1i, m2i, n1i, n2i, sd1i, sd2i, tobs)
ri |
A vector of length two containing the raw correlation coefficients of the original study and replication |
ni |
A vector of length two containing the sample size of the original study and replication for the raw correlation coefficient |
m1i |
A vector of length two containing the means in group 1 for the original study and replication for two-independent means |
m2i |
A vector of length two containing the means in group 2 for the original and replication for two-independent means |
n1i |
A vector of length two containing the sample sizes in group 1 for the original study and replication for two-independent means |
n2i |
A vector of length two containing the sample sizes in group 2 for the original study and replication for two-independent means |
sd1i |
A vector of length two containing the standard deviations in group 1 for the original study and replication for two-independent means |
sd2i |
A vector of length two containing the standard deviations in group 2 for the original study and replication for two-independent means |
tobs |
A vector of length two containing the t-values of the original study and replication |
The function computes posterior probabilities (assuming a uniform prior distribution) for four true effect sizes (no, small, medium, and large) based on an original study and replication. For more information see van Aert and van Assen (2016).
Two different effect size measures can be used as input for the snapshot.naive
function: two-independent means and raw correlation coefficients.
Analyzing two-independent means can be done by either providing
the function group means (m1i
and m2i
), standard deviations
(sd1i
and sd2i
), and sample sizes (n1i
and n2i
) or
t-values (tobs
) and sample sizes (n1i
and n2i
).See the Example section for
an example. Raw correlation coefficients can be analyzed by supplying ri
and ni
to the snapshot.naive
.
The snapshot.naive
function returns a data frame with posterior
probabilities for no (p.0
), small (p.sm
), medium (p.me
),
and large (p.la
) true effect size.
Robbie C.M. van Aert [email protected]
van Aert, R.C.M. & van Assen, M.A.L.M. (2017). Bayesian evaluation of effect size after replicating an original study. PLoS ONE, 12(4), e0175302. doi:10.1371/journal.pone.0175302
### Example as presented on page 491 in Maxwell, Lau, and Howard (2015) snapshot_naive(ri = c(0.243, 0.114), ni = c(80, 172))
### Example as presented on page 491 in Maxwell, Lau, and Howard (2015) snapshot_naive(ri = c(0.243, 0.114), ni = c(80, 172))
Function for parametric bootstrapping procedure to estimate the variability in outcomes' effect size in case of Fisher-z transformed correlations as effect size measure.
var_boot_fis(ri, n, r, dv = 10, reps = 1000)
var_boot_fis(ri, n, r, dv = 10, reps = 1000)
ri |
A vector with Pearson correlation coefficients in a primary study (see Details) |
n |
A numerical value specifying the total sample size of a primary study |
r |
A numerical value specifying the Pearson correlation coefficient between variables h and m (see Details) |
dv |
An integer specifying the total number of dependent measures (default is 10, see Details) |
reps |
An integer specifying the number of bootstrap replications (default is 1,000) |
In case of three variables (l, h, and m), overlapping Fisher-z transformed correlation coefficients can be computed between variables l and h and variables l and m. The function computes the variance of the two overlapping Fisher-z transformed correlation coefficients using a parametric bootstrap procedure. For more information see van Aert & Wicherts (2023).
The vector ri
can contain a single Pearson correlation coefficient or
multiple coefficients if information on more than one outcome is
available. The integer dv
is an optional argument to specify the expected
number of outcomes used in a primary study. This argument can be any
value between 2 and infinity. Larger values yield more accurate estimates of
the variance but slow down the bootstrap procedure.
The variance that is computed with this function can be used to correct for outcome reporting bias by including the variance as a moderator in a (multivariate) meta-analysis. Please see van Aert & Wicherts (2023) for more information.
The var_boot_fis
function returns a numerical value that is the
variance of multiple correlated Fisher-z transformed correlations.
Robbie C.M. van Aert [email protected]
van Aert, R.C.M. & Wicherts, J.M. (2023). Correcting for outcome reporting bias in a meta-analysis: A meta-regression approach. Behavior Research Methods.
### Compute variance for an artificial example var_boot_fis(ri = 0, n = 100, r = 0.3)
### Compute variance for an artificial example var_boot_fis(ri = 0, n = 100, r = 0.3)
Function for parametric bootstrapping procedure to estimate the variability in outcomes' effect size in case of raw mean difference as effect size measure.
var_boot_rmd(sd1i, sd2i, n1i, n2i, r, dv = 10, reps = 1000)
var_boot_rmd(sd1i, sd2i, n1i, n2i, r, dv = 10, reps = 1000)
sd1i |
A vector of standard deviations of the outcomes in group 1 (see Details) |
sd2i |
A vector of standard deviations of the outcomes in group 2 (see Details) |
n1i |
An integer specifying the sample size of group 1 |
n2i |
An integer specifying the sample size of group 2 |
r |
A numerical value specifying the Pearson correlation coefficient between participants' scores on the different outcomes |
dv |
An integer specifying the total number of outcomes (default is 10, see Details) |
reps |
An integer specifying the number of bootstrap replications (default is 1,000) |
Multiple raw mean differences can be computed in case of two groups and multiple outcomes. The function estimates the variance of raw mean differences given a correlation among the outcomes using a parametric bootstrap procedure. For more information see van Aert & Wicherts (2023).
The vectors sd1i
and sd2i
can contain a single standard deviation
or multiple standard deviations if information on more than one outcome
is available. The integer dv
is an optional argument to specify
the expected number of outcomes used in a primary study. This argument
can be any value between 2 and infinity. Larger values yield more accurate
estimates of the variance but slow down the bootstrap procedure.
The variance that is estimated with this function can be used to correct for outcome reporting bias by including the variance as a moderator in a (multivariate) meta-analysis. Please see van Aert & Wicherts (2023) for more information.
The var_boot_rmd
function returns a numerical value that is an
estimate of the variance of multiple correlated raw mean differences.
Robbie C.M. van Aert [email protected]
van Aert, R.C.M. & Wicherts, J.M. (2023). Correcting for outcome reporting bias in a meta-analysis: A meta-regression approach. Behavior Research Methods.
### Compute variance for an artificial example var_boot_rmd(sd1i = c(0.8, 1.2), sd2i = c(0.85, 1.15), n1i = 100, n2i = 95, r = 0.3)
### Compute variance for an artificial example var_boot_rmd(sd1i = c(0.8, 1.2), sd2i = c(0.85, 1.15), n1i = 100, n2i = 95, r = 0.3)
Function for computing the variance of the difference between two overlapping Fisher-z transformed correlation coefficients.
var_dif_fis(n, r, rho)
var_dif_fis(n, r, rho)
n |
A numerical value specifying the total sample size of a primary study |
r |
A numerical value specifying the Pearson correlation coefficient between variables h and m (see Details) |
rho |
A numerical value specifying the Pearson correlation coefficient between variables l and h and variables h and m (see Details) |
In case of three variables (l, h, and m), overlapping Fisher-z transformed correlation coefficients can be computed between variables l and h and variables l and m. The function computes the variance of the difference between these two overlapping Fisher-z transformed correlations. For a derivation of this variance see van Aert & Wicherts (2023).
The variance that is computed with this function can be used to correct for outcome reporting bias by including the variance as a moderator in a (multivariate) meta-analysis. Please see van Aert & Wicherts (2023) for more information.
The var_dif_fis
function returns a numerical value that is the
variance of the difference of two overlapping Fisher-z transformed correlations
given n, r, and rho.
Robbie C.M. van Aert [email protected]
van Aert, R.C.M. & Wicherts, J.M. (2023). Correcting for outcome reporting bias in a meta-analysis: A meta-regression approach. Behavior Research Methods.
### Compute variance for an artificial example var_dif_fis(n = 100, r = 0.3, rho = 0.5)
### Compute variance for an artificial example var_dif_fis(n = 100, r = 0.3, rho = 0.5)
Function for computing the variance of the difference between two raw mean differences.
var_dif_rmd(sd1i, sd2i, n1i, n2i, r)
var_dif_rmd(sd1i, sd2i, n1i, n2i, r)
sd1i |
A vector of standard deviations of the outcomes in group 1 (see Details) |
sd2i |
A vector of standard deviations of the outcomes in group 2 (see Details) |
n1i |
An integer specifying the sample size of group 1 |
n2i |
An integer specifying the sample size of group 2 |
r |
A numerical value specifying the Pearson correlation coefficient between participants' scores on the different outcomes |
Multiple raw mean differences can be computed in case of two groups and multiple outcomes. The function computes the variance of the difference of two raw mean differences given a correlation between the outcomes. For a derivation of this variance see the supplemental materials of van Aert & Wicherts (2023).
The vectors sd1i
and sd2i
can contain a single standard deviation
or multiple standard deviations if information on more than one outcome
measure is available.
The variance that is computed with this function can be used to correct for outcome reporting bias by including the variance as a moderator in a (multivariate) meta-analysis. Please see van Aert & Wicherts (2023) for more information.
The var_dif_rmd
function returns a numerical value that is the
variance of the difference of two raw mean differences given r.
Robbie C.M. van Aert [email protected]
van Aert, R.C.M. & Wicherts, J.M. (2023). Correcting for outcome reporting bias in a meta-analysis: A meta-regression approach. Behavior Research Methods.
### Compute variance for an artificial example var_dif_rmd(sd1i = c(0.8, 1.2), sd2i = c(0.85, 1.15), n1i = 100, n2i = 95, r = 0.3)
### Compute variance for an artificial example var_dif_rmd(sd1i = c(0.8, 1.2), sd2i = c(0.85, 1.15), n1i = 100, n2i = 95, r = 0.3)
Function for estimating the population variance of correlated outcomes' effect size within a primary study.
var_pop(v, r)
var_pop(v, r)
v |
A numerical value specifying the sampling variance of the effect size (see Details) |
r |
A numerical value specifying the Pearson correlation coefficient between the outcomes (see Details) |
This function estimates the population variance of the effect size of
correlated outcomes within a study. That is, it estimates the population
variance from a single draw of a multivariate normal distribution. The function
assumes equal true effect size of all outcomes, equal sampling variances of
the outcomes' effect size, and equal correlation (i.e., r
) among the
outcomes.
For a derivation of this estimator see van Aert & Wicherts (2023).
The variance that is computed with this function can be used to correct for outcome reporting bias by including the variance as a moderator in a (multivariate) meta-analysis. Please see van Aert & Wicherts (2023) for more information.
The var_pop
function returns a numerical value that is the
estimate of the population variance of correlated outcomes' effect size
given v and r.
Robbie C.M. van Aert [email protected]
van Aert, R.C.M. & Wicherts, J.M. (2023). Correcting for outcome reporting bias in a meta-analysis: A meta-regression approach. Behavior Research Methods.
### Compute variance for an artificial example var_pop(v = 0.1, r = 0.3)
### Compute variance for an artificial example var_pop(v = 0.1, r = 0.3)