Package: pleioh2g Type: Package Title: Estimation of Pleiotropic Heritability from Genome-Wide Association Studies (GWAS) Summary Statistics Version: 0.1.3 Authors@R: c( person(given = "Yujie", family = "Zhao", role = c("aut", "cre"), email = "yujiezhao@hsph.harvard.edu") ) Description: Provides tools to compute unbiased pleiotropic heritability estimates of complex diseases from genome-wide association studies (GWAS) summary statistics. We estimate pleiotropic heritability from GWAS summary statistics by estimating the proportion of variance explained from an estimated genetic correlation matrix (Bulik-Sullivan et al. 2015 ) and employing a Monte-Carlo bias correction procedure to account for sampling noise in genetic correlation estimates. License: GPL-3 Encoding: UTF-8 LazyData: true Depends: R (>= 2.10) RoxygenNote: 7.3.2 Imports: data.table, dplyr, stats, rlang, mvtnorm, fs, arrow, checkmate, cli, gdata, glue, purrr, tibble, vroom Suggests: knitr, rmarkdown, testthat (>= 3.0.0) Config/testthat/edition: 3 VignetteBuilder: knitr Language: en-US NeedsCompilation: no Packaged: 2026-07-09 10:10:26 UTC; root Author: Yujie Zhao [aut, cre] Maintainer: Yujie Zhao Repository: https://cran.r-universe.dev Date/Publication: 2026-06-09 08:40:02 UTC RemoteUrl: https://github.com/cran/pleioh2g RemoteRef: HEAD RemoteSha: 3f1b7cdc3c25b813a828c415c8c3531c93f61956