Package: multipleOutcomes Title: Joint Covariance and Treatment-Effect Tests for Multiple Outcomes Version: 0.18.1 Authors@R: person("Han", "Zhang", , "zhangh.ustc@gmail.com", role = c("aut", "cre")) Description: Fits generalized linear models, Cox proportional-hazards models, log-rank tests, generalized estimating equations, mixed models with repeated measures, Kaplan-Meier curves, quantile differences, and hierarchical net-benefit (win-difference) and log win-ratio statistics jointly across multiple endpoints, and returns the full asymptotic covariance matrix linking them. Implements PATED (Prognostic Assisted Treatment Effect Detection), a randomized-trial method that exploits balanced prognostic covariates to tighten standard errors and increase statistical power without introducing bias. URL: https://github.com/zhangh12/multipleOutcomes, https://zhangh12.github.io/multipleOutcomes/ BugReports: https://github.com/zhangh12/multipleOutcomes/issues License: MIT + file LICENSE Encoding: UTF-8 Imports: dplyr, ggplot2, ggpubr, mmrm (>= 0.3.15), mvtnorm, rlang, sandwich, stringr, survival, tidyr, tidyselect Suggests: asaur, coin, iBST, invGauss, JM, knitr, momentfit, numDeriv, pec, rmarkdown, testthat (>= 3.0.0) Depends: R (>= 3.5) LazyData: true Config/roxygen2/version: 8.0.0 RoxygenNote: 7.3.3 NeedsCompilation: yes Packaged: 2026-10-07 09:37:19 UTC; root Author: Han Zhang [aut, cre] Maintainer: Han Zhang Repository: https://cran.r-universe.dev Date/Publication: 2026-06-15 07:40:02 UTC RemoteUrl: https://github.com/cran/multipleOutcomes RemoteRef: HEAD RemoteSha: 402e22ca4d0005eae1372d6d31334789b2cbcb2f