Package: msce Type: Package Title: Hazard of Multi-Stage Clonal Expansion Models Version: 1.0.2 Date: 2025-12-05 Authors@R: c(person(given = "Cristoforo", family = "Simonetto", role = c("aut", "cre"), email = "cristoforo.simonetto@ph.tum.de", comment = c(ORCID = "0000-0003-4816-3514")), person(given = c("Jan", "Christian"), family = "Kaiser", role = "ctb")) Author: Cristoforo Simonetto [aut, cre] (ORCID: ), Jan Christian Kaiser [ctb] Maintainer: Cristoforo Simonetto Description: Functions to calculate hazard and survival function of Multi-Stage Clonal Expansion Models used in cancer epidemiology. For the Two-Stage Clonal Expansion Model an exact solution is implemented assuming piecewise constant parameters, see Heidenreich, Luebeck, Moolgavkar (1997) . Numerical solutions are provided for its extensions, see also Little, Vineis, Li (2008) . License: GPL (>= 2) Imports: Rcpp (>= 1.0.3), RcppParallel (>= 5.0.0) LinkingTo: Rcpp, RcppParallel Encoding: UTF-8 RoxygenNote: 7.3.3 Suggests: knitr, rmarkdown, testthat VignetteBuilder: knitr NeedsCompilation: yes Packaged: 2026-06-15 11:41:13 UTC; root Repository: https://cran.r-universe.dev Date/Publication: 2025-12-17 02:21:06 UTC RemoteUrl: https://github.com/cran/msce RemoteRef: HEAD RemoteSha: 826601c801598234a155928326e8c47bc28badf1