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# CITATION file created with {cffr} R package
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cff-version: 1.2.0
message: 'To cite package "mectx" in publications use:'
type: software
license: MIT
title: 'mectx: MEchanistic Clustering - Treatment eXposure Framework'
version: 1.1.1
abstract: Implements the MEC-TX (MEchanistic Clustering - Treatment eXposure) framework
  for encoding, clustering, and survival analysis of real-world oncology treatment
  timelines. Provides functions for normalising medication records, computing treatment
  intervals, performing k-means clustering in PCA space, assigning line-of-therapy
  labels, and comparing survival outcomes across treatment groups. Designed for use
  with registry-based cohorts such as the ORIEN AVATAR dataset. Methods follow the
  digital-twin framework described in Dhrubo and Spakowicz (2026) <https://github.com/spakowiczlab/mec-tx>.
  treatment timelines using the MEC-TX digital-twin framework.
authors:
- family-names: Dhrubo
  given-names: Dipankor
  email: dhrubo.2@osu.edu
- family-names: Spakowicz
  given-names: Daniel
  email: daniel.spakowicz@osumc.edu
  orcid: https://orcid.org/0000-0003-2314-6435
repository: https://cran.r-universe.dev
commit: 71351649ec6489fabb1bb7bf4afe8b868e6ea2f3
date-released: '2026-04-27'
contact:
- family-names: Dhrubo
  given-names: Dipankor
  email: dhrubo.2@osu.edu