Package: gst Title: Global Statistical Tests for Multiple Endpoints Version: 0.4.0 Authors@R: c( person("Lerong", "Li", , "leli@sarepta.com", role = c("aut", "led")), person("Anthony", "Pileggi", , "APileggi@sarepta.com", role = c("aut")), person("Xiaolong", "Luo", , "XLuo@sarepta.com", role = c("aut")), person("Xiao", "Ni", , "mooncase@gmail.com", role = c("aut", "cre")), person("Sarepta Therapeutics Inc.", , role = c("cph", "fnd")), person("Stephen", "Knapp", , "sknapp@sarepta.com", role = c("ctb"), comment = c(ORCID = "0000-0002-5101-4555")), person("Preston", "Burns", , "PrBurns@Sarepta.com", role = c("ctb")) ) Description: Design and evaluate global statistical tests (GST) that combine several endpoints into one test, including O'Brien's ordinary and generalized least squares tests (O'Brien (1984) ), power and sample size calculations, and an O'Brien-based truncated closed testing procedure (Luo et al. (2025) ). Two 'shiny' applications support interactive power calculation and the creation of forest plots for multiple endpoints from summary statistics. License: Apache License (== 2.0) URL: https://xni7.github.io/gst/, https://github.com/xni7/gst BugReports: https://github.com/xni7/gst/issues Encoding: UTF-8 RoxygenNote: 7.3.3 Depends: R (>= 4.1.0) Imports: dplyr, forestploter, magrittr, MASS, multcomp, stats, parallel, readr, rhandsontable, shiny, shinyWidgets, htmltools, tidyr, plotly, grDevices, grid, pwr, DT, purrr, tibble, bslib, bsicons, datapasta, sortable, stringr, rclipboard, ggplot2, mvtnorm, reactable, rlang Suggests: knitr, rmarkdown, gt, testthat (>= 3.0.0) VignetteBuilder: knitr Config/testthat/edition: 3 NeedsCompilation: no Packaged: 2026-11-07 22:34:13 UTC; root Author: Lerong Li [aut, led], Anthony Pileggi [aut], Xiaolong Luo [aut], Xiao Ni [aut, cre], Sarepta Therapeutics Inc. [cph, fnd], Stephen Knapp [ctb] (ORCID: ), Preston Burns [ctb] Maintainer: Xiao Ni Repository: https://cran.r-universe.dev Date/Publication: 2026-11-07 21:00:28 UTC RemoteUrl: https://github.com/cran/gst RemoteRef: HEAD RemoteSha: d85276b3ae60c2d6961f238af7bb902a783c7153