Package: graposas Type: Package Title: Graphical Approach Optimal Sample Size Version: 1.0.0 Date: 2023-07-30 Authors@R: c( person("Jiangtao", "Gou", email = "gouRpackage@gmail.com", role = c("aut", "cre")), person("Fengqing (Zoe)", "Zhang", role = "aut")) Description: Graphical approach provides a useful framework for multiplicity adjustment in clinical trials with multiple endpoints. This package includes statistical methods to optimize sample size over initial weight and transition probability in a graphical approach under a common setting, which is to use marginal power for each endpoint in a trial design. See Zhang, F. and Gou, J. (2023). Sample size optimization for clinical trials using graphical approaches for multiplicity adjustment, Technical Report. License: GPL-3 Encoding: UTF-8 Depends: R (>= 4.2.0) Imports: GA (>= 3.0.0), graphics (>= 4.2.0), mvtnorm (>= 1.1.0), stats (>= 4.0.0) RoxygenNote: 7.2.3 NeedsCompilation: no Packaged: 2026-09-25 07:18:04 UTC; root Author: Jiangtao Gou [aut, cre], Fengqing (Zoe) Zhang [aut] Maintainer: Jiangtao Gou Repository: https://cran.r-universe.dev Date/Publication: 2023-08-17 08:30:55 UTC RemoteUrl: https://github.com/cran/graposas RemoteRef: HEAD RemoteSha: c99d3679e29c1b325f10fe8a042bf7b493897685