Package: epoc 0.2.6-1.1

Tobias Abenius

epoc: Endogenous Perturbation Analysis of Cancer

Estimates sparse matrices A or G using fast lasso regression from mRNA transcript levels Y and CNA profiles U. Two models are provided, EPoC A where AY + U + R = 0 and EPoC G where Y = GU + E, the matrices R and E are so far treated as noise. For details see the manual page of 'lassoshooting' and the article Rebecka Jörnsten, Tobias Abenius, Teresia Kling, Linnéa Schmidt, Erik Johansson, Torbjörn E M Nordling, Bodil Nordlander, Chris Sander, Peter Gennemark, Keiko Funa, Björn Nilsson, Linda Lindahl, Sven Nelander (2011) <doi:10.1038/msb.2011.17>.

Authors:Rebecka Jornsten, Tobias Abenius, Sven Nelander

epoc_0.2.6-1.1.tar.gz
epoc_0.2.6-1.1.tar.gz(r-4.5-noble)epoc_0.2.6-1.1.tar.gz(r-4.4-noble)
epoc_0.2.6-1.1.tgz(r-4.4-emscripten)epoc_0.2.6-1.1.tgz(r-4.3-emscripten)
epoc.pdf |epoc.html
epoc/json (API)

# Install 'epoc' in R:
install.packages('epoc', repos = c('https://cran.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Datasets:
  • synth - Blinded cancer mRNA, CNA and survival data

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

1.48 score 3 scripts 185 downloads 3 mentions 16 exports 8 dependencies

Last updated 5 years agofrom:f580787c99. Checks:OK: 1 NOTE: 1. Indexed: yes.

TargetResultDate
Doc / VignettesOKNov 13 2024
R-4.5-linuxNOTENov 13 2024

Exports:as.graph.EPOCAas.graph.EPOCGepoc.bootplotepoc.bootstrapepoc.finalepoc.lambdamaxepoc.survivalepoc.svdepoc.svdplotepoc.validationepocAepocGmodelselPlotplapplyplot.bootsizewrite.sif

Dependencies:elasticnetirrlarslassoshootinglatticelpSolveMatrixsurvival

Readme and manuals

Help Manual

Help pageTopics
EPoCas.graph.EPOCA as.graph.EPOCG coef.EPOCA coef.EPOCG epoc epoc.lambdamax epocA epocG predict.EPOCA predict.EPOCG print.EPOCA print.EPOCG summary.EPOCA summary.EPOCG write.sif
epoc.bootstrapepoc.bootplot epoc.bootstrap epoc.final plot.bootsize
epoc.survivalepoc.survival epoc.svd epoc.svdplot plot.EPoC.survival print.summary.EPoC.survival summary.EPoC.survival
epoc.validationepoc.validation
Plot BIC, Mallow's Cp and lambdamodelselPlot plot.EPOCA plot.EPOCG
Parallell list applyplapply
Plot model validation criteriaplot.EPoC.validation plot.EPoC.validation.pred plot.EPoC.validation.W
Blinded cancer mRNA, CNA and survival datasynth