# -------------------------------------------- # CITATION file created with {cffr} R package # See also: https://docs.ropensci.org/cffr/ # -------------------------------------------- cff-version: 1.2.0 message: 'To cite package "carts" in publications use:' type: software license: Apache-2.0 title: 'carts: Simulation-Based Assessment of Covariate Adjustment in Randomized Trials' version: 0.1.0 doi: 10.32614/CRAN.package.carts abstract: Monte Carlo simulation framework for different randomized clinical trial designs with a special emphasis on estimators based on covariate adjustment. The package implements regression-based covariate adjustment (Rosenblum & van der Laan (2010) ) and a one-step estimator (Van Lancker et al (2024) ) for trials with continuous, binary and count outcomes. The estimation of the minimum sample-size required to reach a specified statistical power for a given estimator uses bisection to find an initial rough estimate, followed by stochastic approximation (Robbins-Monro (1951) ) to improve the estimate, and finally, a grid search to refine the estimate in the neighborhood of the current best solution. authors: - family-names: Sommer given-names: Benedikt email: benediktsommer92@gmail.com - family-names: Holst given-names: Klaus K. email: klaus@holst.it - family-names: Shamsi given-names: Foroogh email: foroogh.shamsi1@gmail.com repository: https://cran.r-universe.dev repository-code: https://github.com/NovoNordisk-OpenSource/carts commit: 0a2bd54cab5b7dd2807d1b2c04e70edd1453b1eb url: https://novonordisk-opensource.github.io/carts/ date-released: '2025-11-13' contact: - family-names: Sommer given-names: Benedikt email: benediktsommer92@gmail.com