Package: boinet
Version: 1.5.0
Title: Conduct Simulation Study of Bayesian Optimal Interval Design
        with BOIN-ET Family
Authors@R: c(
    person(given  = "Yusuke",
           family = "Yamaguchi",
           role   = c("aut","cre"),
           email  = "yamagubed@gmail.com"),
    person(given  = "Kentaro",
           family = "Takeda",
           role   = c("aut")))
Description: Bayesian optimal interval based on both efficacy and
        toxicity outcomes (BOIN-ET) design is a model-assisted oncology
        phase I/II trial design, aiming to establish an optimal
        biological dose accounting for efficacy and toxicity in the
        framework of dose-finding. Some extensions of BOIN-ET design
        are also available to allow for time-to-event efficacy and
        toxicity outcomes based on cumulative and pending data
        (time-to-event BOIN-ET: TITE-BOIN-ET), ordinal graded efficacy
        and toxicity outcomes (generalized BOIN-ET: gBOIN-ET), and
        their combination (TITE-gBOIN-ET). 'boinet' is a package to
        implement the BOIN-ET design family and supports the conduct of
        simulation studies to assess operating characteristics of
        BOIN-ET, TITE-BOIN-ET, gBOIN-ET, and TITE-gBOIN-ET, where users
        can choose design parameters in flexible and straightforward
        ways depending on their own application.
License: MIT + file LICENSE
Encoding: UTF-8
RoxygenNote: 7.3.3
Depends: R (>= 4.1.0)
Imports: Iso, mfp, copula, gt, tibble, shiny, shinydashboard, DT,
        plotly, ggplot2, rhandsontable, shinyBS
Suggests: testthat (>= 3.0.0), knitr, rmarkdown, dplyr (>= 1.0.0),
VignetteBuilder: knitr
Config/testthat/edition: 3
NeedsCompilation: no
Packaged: 2026-07-07 06:08:30 UTC; root
Author: Yusuke Yamaguchi [aut, cre], Kentaro Takeda [aut]
Maintainer: Yusuke Yamaguchi <yamagubed@gmail.com>
Repository: https://cran.r-universe.dev
Date/Publication: 2025-10-26 19:20:02 UTC
RemoteUrl: https://github.com/cran/boinet
RemoteRef: HEAD
RemoteSha: d28e0e4732e32db4a8d4bbcb655f03a5c7acf3b4