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At design stage, the package\nassists in selecting a subset of individuals that will be\nsequenced for phase 2 via alternative approaches, including a\nflexible genetic algorithm (GA) for near-optimal designs. Once\nphase 2 data have been collected, the package implements\nmethods to analyse phase 1 and phase 2 data together using\nsemi-parametric regression models via the\nexpectation-maximization (EM) algorithm. For more details see\nEspin-Garcia, Craiu and Bull (2018) \nand Espin-Garcia, Craiu and Bull (2021) .", "License": "GPL (>= 2)", "URL": "https://github.com/egosv/twoPhaseGAS", "BugReports": "https://github.com/egosv/twoPhaseGAS/issues", "VignetteBuilder": "knitr", "Encoding": "UTF-8", "RoxygenNote": "7.3.2", "Config/testthat/edition": "3", "NeedsCompilation": "no", "Packaged": { "Date": "2026-05-27 14:37:52 UTC", "User": "root" }, "Author": "Osvaldo Espin-Garcia [aut, cre], Apostolos Dimitromanolakis\n[aut], Radu V Craiu [ths], Shelley B Bull [ths]", "Maintainer": "Osvaldo Espin-Garcia ", "Repository": "https://cran.r-universe.dev", "Date/Publication": "2026-05-27 10:00:02 UTC", "RemoteUrl": "https://github.com/cran/twoPhaseGAS", "RemoteRef": "HEAD", "RemoteSha": "5f85bc43c06f44e49f413af5418eca64eb5bb4d9", "MD5sum": "39f001b9c539dc975e336dfef06cbd88", "_user": "cran", "_type": "src", "_file": "twoPhaseGAS_1.2.5.tar.gz", "_fileid": 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