{ "_id": "6a1014dfacfb0bcc41c83ccb", "Package": "triggerstrategy", "Title": "Trigger Strategy in Clinical Trials", "Version": "1.2.0", "Date": "2023-07-02", "Authors@R": "c(\nperson(\"Jiangtao\", \"Gou\", email = \"gouRpackage@gmail.com\", role = c(\"aut\", \"cre\")),\nperson(\"Fengqing (Zoe)\", \"Zhang\", role = \"aut\"))", "Description": "The trigger strategy is a general framework for a\nmultistage statistical design with multiple hypotheses,\nallowing an adaptive selection of interim analyses. The\nselection of interim stages can be associated with some\nprespecified endpoints which serve as the trigger. This\nselection allows us to refine the critical boundaries in\nhypotheses testing procedures, and potentially increase the\nstatistical power. This package includes several trial designs\nusing the trigger strategy. See Gou, J. (2023), \"Trigger\nstrategy in repeated tests on multiple hypotheses\", Statistics\nin Biopharmaceutical Research, 15(1), 133-140, and Gou, J.\n(2022), \"Sample size optimization and initial allocation of the\nsignificance levels in group sequential trials with multiple\nendpoints\", Biometrical Journal, 64(2), 301-311.", "License": "GPL-3", "Encoding": "UTF-8", "RoxygenNote": "7.2.3", "NeedsCompilation": "no", "Packaged": { "Date": "2026-05-15 05:55:12 UTC", "User": "root" }, "Author": "Jiangtao Gou [aut, cre], Fengqing (Zoe) Zhang [aut]", "Maintainer": "Jiangtao Gou ", "Repository": "https://cran.r-universe.dev", "Date/Publication": "2023-07-04 13:40:02 UTC", "RemoteUrl": "https://github.com/cran/triggerstrategy", "RemoteRef": "HEAD", "RemoteSha": "6d15e9f81567f76ecadcfc4db044238f2b408412", "MD5sum": "5adb89ca779da3c0758618d938184ef7", "_user": "cran", "_type": "src", "_file": "triggerstrategy_1.2.0.tar.gz", "_fileid": "44da69287c5c2bd6608f6f74091185d51961c2aa741793f42d5e2a941b1bb646", "_filesize": 141966, "_sha256": "44da69287c5c2bd6608f6f74091185d51961c2aa741793f42d5e2a941b1bb646", "_created": "2026-05-15T05:55:12.000Z", "_published": "2026-05-22T08:33:35.908Z", "_distro": "noble", "_jobs": [ { "job": 77344521588, "time": 161, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "7011030684" }, { "job": 77344521494, "time": 111, "config": "linux-release-x86_64", "r": "4.6.0", "check": "OK", "artifact": "7011021327" }, { "job": 77344521497, "time": 144, "config": "source", "r": "4.6.0", "check": "OK", "artifact": "7010997417" }, { "job": 77344521148, "time": 97, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "7156241701" } ], "_buildurl": "https://github.com/r-universe/cran/actions/runs/25902749979", "_status": "success", "_host": "GitHub-Actions", "_upstream": "https://github.com/cran/triggerstrategy", "_commit": { "id": "6d15e9f81567f76ecadcfc4db044238f2b408412", "author": "Jiangtao Gou ", "committer": "cran-robot ", "message": "version 1.2.0\n", "time": 1688478002 }, "_maintainer": { "name": "Jiangtao Gou", "email": "gourpackage@gmail.com" }, "_registered": true, "_dependencies": [ { "package": "R", "version": ">= 4.2.0", "role": "Depends" }, { "package": "GA", "version": ">= 3.0.0", "role": "Imports" }, { "package": "ldbounds", "version": ">= 2.0.0", "role": "Imports" }, { "package": "mvtnorm", "version": ">= 1.1.0", "role": "Imports" }, { "package": "nleqslv", "version": ">= 3.0.0", "role": "Imports" }, { "package": "stats", "version": ">= 4.0.0", "role": "Imports" } ], "_owner": "cran", "_selfowned": false, "_usedby": 0, "_updates": [], "_tags": [], "_stars": 0, "_userbio": { "uuid": 6899542, "type": "organization", "name": "cran", "description": "Unofficial read-only mirror of all CRAN R packages" }, "_downloads": { "count": 178, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/triggerstrategy" }, "_searchresults": 0, "_rbuild": "4.6.0", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/triggerstrategy.html", "manual.pdf" ], "_realowner": "cran", "_cranurl": false, "_releases": [ { "version": "1.0.4", "date": "2021-05-31" }, { "version": "1.1.0", "date": "2021-06-22" }, { "version": "1.2.0", "date": "2023-07-04" } ], "_exports": [ "alpha2boundary", "boundary2alpha", "corrMatGenerator", "gbounds", "marginalPwR", "psPwRbhmb", "psPwRtrigger", "sBoundsPh2", "sErrRphInt2", "solveAlphaXsampleSize", "solveAlphaXsampleSizeGA", "sPwRholm", "sPwRholmye", "sPwRnaiveBonf", "sPwRph2", "sPwRtrigger" ], "_help": [ { "page": "alpha2boundary", "title": "Convert cumulative alpha levels to normal critical boundaries", "topics": [ "alpha2boundary" ] }, { "page": "boundary2alpha", "title": "Convert normal critical boundaries to cumulative alpha levels.", "topics": [ "boundary2alpha" ] }, { "page": "corrMatGenerator", "title": "Correlation matrix generator", "topics": [ "corrMatGenerator" ] }, { "page": "gbounds", "title": "Critical boundary in group sequential trials", "topics": [ "gbounds" ] }, { "page": "marginalPwR", "title": "Marginal Power Rate", "topics": [ "marginalPwR" ] }, { "page": "psPwRbhmb", "title": "Powers of testing the primary and secondary hypotheses", "topics": [ "psPwRbhmb" ] }, { "page": "psPwRtrigger", "title": "Powers of testing the primary and secondary hypotheses using trigger strategy", "topics": [ "psPwRtrigger" ] }, { "page": "sBoundsPh2", "title": "Critical boundaries for the secondary endpoint in the partially hierarchical group sequential design", "topics": [ "sBoundsPh2" ] }, { "page": "sErrRphInt2", "title": "Type I error rate of the overall null hypothesis using the partial hierarchical design", "topics": [ "sErrRphInt2" ] }, { "page": "solveAlphaXsampleSize", "title": "Sample size calculation", "topics": [ "solveAlphaXsampleSize" ] }, { "page": "solveAlphaXsampleSizeGA", "title": "Sample size calculation using Genetic Algorithms", "topics": [ "solveAlphaXsampleSizeGA" ] }, { "page": "sPwRholm", "title": "Power of testing the secondary hypothesis using Holm", "topics": [ "sPwRholm" ] }, { "page": "sPwRholmye", "title": "Power of testing the secondary hypothesis using Holm-Ye", "topics": [ "sPwRholmye" ] }, { "page": "sPwRnaiveBonf", "title": "Power of testing the secondary hypothesis using Bonferroni", "topics": [ "sPwRnaiveBonf" ] }, { "page": "sPwRph2", "title": "Power of testing the secondary hypothesis in partially hierarchical design", "topics": [ "sPwRph2" ] }, { "page": "sPwRtrigger", "title": "Power of testing the secondary hypothesis using Trigger strategy", "topics": [ "sPwRtrigger" ] } ], "_rundeps": [ "cli", "codetools", "crayon", "foreach", "GA", "iterators", "ldbounds", "mvtnorm", "nleqslv", "Rcpp", "RcppArmadillo" ], "_score": 1, "_indexed": true, "_nocasepkg": "triggerstrategy", "_universes": [ "cran" ], "_binaries": [ { "r": "4.7.0", "os": "linux", "version": "1.2.0", "date": "2026-05-15T05:57:55.000Z", "distro": "noble", "commit": "6d15e9f81567f76ecadcfc4db044238f2b408412", "fileid": "6d9aaa6fbea47bc637f45dd52a16266f6f8e704319f2b7f5dedd6dc13448c0dd", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/cran/actions/runs/25902749979" }, { "r": "4.6.0", "os": "linux", "version": "1.2.0", "date": "2026-05-15T05:57:04.000Z", "distro": "noble", "commit": "6d15e9f81567f76ecadcfc4db044238f2b408412", "fileid": "38e78952dea787df3401cbd76024b052fcb001425b03c5ccb0502cbded1df090", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/cran/actions/runs/25902749979" }, { "r": "4.6.0", "os": "wasm", "version": "1.2.0", "date": "2026-05-22T08:33:23.000Z", "commit": "6d15e9f81567f76ecadcfc4db044238f2b408412", "fileid": "219cd318ffa31a036c364578f3809b37831786accb2c47cf63430d662ac47404", "status": "success", "buildurl": "https://github.com/r-universe/cran/actions/runs/25902749979" } ] }