{ "_id": "6a16ac9cacfb0bcc41d84420", "Package": "refreg", "Type": "Package", "Title": "Conditional Multivariate Reference Regions", "Version": "0.1.1", "Authors@R": "c(\nperson(\"Oscar\", \"Lado-Baleato\",email=\"oscarlado.baleato@usc.es\", role =c(\"cre\",\"aut\")),\nperson(\"Javier\", \"Roca-Pardinas\", email=\"roca@uvigo.es\", role =c(\"aut\", \"ctb\")),\nperson(\"Carmen\", \"Cadarso-Suarez\",email=\"carmen.cadarso@usc.es\", role = c(\"aut\", \"ths\")),\nperson(\"Gude\",\"Francisco\",email=\"francisco.gude.sampedro@sergas.es\", role = c(\"aut\", \"ths\"))\n)", "Maintainer": "Oscar Lado-Baleato ", "Description": "An R package for estimating conditional multivariate\nreference regions. The reference region is non parametrically\nestimated using a kernel density estimator. Covariates effects\non the multivariate response means vector and\nvariance-covariance matrix, thus on the region shape, are\nestimated by flexible additive predictors. Continuous\ncovariates non linear effects might be estimated using\npenalized splines smoothers. Confidence intervals for the\ncovariates estimated effects might be derived from bootstrap\nresampling. Kernel density bandwidth can be estimated with\ndifferent methods, including a method that optimize the region\ncoverage. Numerical, and graphical, summaries can be obtained\nby the user in order to evaluate reference region performance\nwith real data. Full mathematical details can be found in\n and .", "License": "GPL-2", "Encoding": "UTF-8", "LazyData": "true", "RoxygenNote": "7.1.2", "NeedsCompilation": "no", "Packaged": { "Date": "2026-05-27 08:30:39 UTC", "User": "root" }, "Author": "Oscar Lado-Baleato [cre, aut], Javier Roca-Pardinas [aut, ctb],\nCarmen Cadarso-Suarez [aut, ths], Gude Francisco [aut, ths]", "Repository": "https://cran.r-universe.dev", "Date/Publication": "2022-04-18 13:20:02 UTC", "RemoteUrl": "https://github.com/cran/refreg", "RemoteRef": "HEAD", "RemoteSha": "40eed0780ac588c843ccce5926f10beb4fed6d3b", "MD5sum": "e1fdedb40f98191c09958f3116037a74", "_user": "cran", "_type": "src", "_file": "refreg_0.1.1.tar.gz", "_fileid": "d588d299d54176aff127c403126ef6453a64541d5f9dda4b7f0c456215a02bc8", "_filesize": 276109, "_sha256": "d588d299d54176aff127c403126ef6453a64541d5f9dda4b7f0c456215a02bc8", "_created": "2026-05-27T08:30:39.000Z", "_published": "2026-05-27T08:34:36.931Z", "_distro": "noble", "_jobs": [ { "job": 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