{ "_id": "6a3adc545cdecea1d67eda8e", "Package": "msprog", "Type": "Package", "Title": "Reproducible Assessment of Disability Course in Multiple\nSclerosis", "Version": "1.0.0", "Authors@R": "c(\nperson(given=\"Noemi\", family=\"Montobbio\", , email=\"noemi.montobbio@gmail.com\", role=c(\"aut\", \"cre\"),\ncomment=c(ORCID = \"0000-0003-0302-393X\")),\nperson(given=\"Francesca\", family=\"Bovis\", role = c(\"rev\")),\nperson(given=\"Luca\", family=\"Carmisciano\", role = c(\"rev\")))", "Description": "Analyse disability course in multiple sclerosis (MS) from\nlongitudinal data. The package provides a flexible framework\nfor identifying disability events under user-specified\ncriteria, allowing adaptation to different study designs and\nendpoints. Tools are included to facilitate transparent and\nreproducible reporting of the settings used in the analysis.\nFor an introduction to the package and illustrative\napplications, see Montobbio et al. (2024)\n.", "Encoding": "UTF-8", "LazyData": "true", "RoxygenNote": "7.3.3", "VignetteBuilder": "knitr", "License": "MIT + file LICENSE", "NeedsCompilation": "no", "Packaged": { "Date": "2026-06-23 19:16:31 UTC", "User": "root" }, "Author": "Noemi Montobbio [aut, cre] (ORCID:\n), Francesca Bovis\n[rev], Luca Carmisciano [rev]", "Maintainer": "Noemi Montobbio ", "Repository": "https://cran.r-universe.dev", "Date/Publication": "2026-06-23 16:00:02 UTC", "RemoteUrl": "https://github.com/cran/msprog", "RemoteRef": "HEAD", "RemoteSha": "82e9caff29d0133b158a2c2e7cfbebe9ffdbc5da", "MD5sum": "4b1fecce141cef3ee0bed19135b6ab58", "_user": "cran", "_type": "src", "_file": "msprog_1.0.0.tar.gz", "_fileid": "0ba43a5245752941fbc54f685d3050c74cd8706494d7a6ed708c5d9a07875adf", "_filesize": 989904, "_sha256": "0ba43a5245752941fbc54f685d3050c74cd8706494d7a6ed708c5d9a07875adf", "_created": "2026-06-23T19:16:31.000Z", "_published": "2026-06-23T19:19:48.651Z", "_distro": "resolute", "_jobs": [ { "job": 83040548737, "time": 133, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "7831027105" }, { "job": 83040548734, "time": 125, "config": "linux-release-x86_64", "r": "4.6.0", "check": "OK", "artifact": "7831023583" }, { "job": 83039889964, "time": 197, "config": "source", "r": "4.6.0", "check": "OK", "artifact": "7830974866" }, { "job": 83040548716, "time": 158, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "7831036863" } ], "_buildurl": "https://github.com/r-universe/cran/actions/runs/28050578151", "_status": "success", "_host": "GitHub-Actions", "_upstream": "https://github.com/cran/msprog", "_commit": { "id": "82e9caff29d0133b158a2c2e7cfbebe9ffdbc5da", "author": "Noemi Montobbio ", "committer": "cran-robot ", "message": "version 1.0.0\n", "time": 1782230402 }, "_maintainer": { "name": "Noemi Montobbio", "email": "noemi.montobbio@gmail.com", "login": "noemimontobbio", "twitter": "@NMontobbio", "description": "", "uuid": 94608349, "orcid": "0000-0003-0302-393X" }, "_registered": true, "_dependencies": [ { "package": "R", "version": ">= 4.1.0", "role": "Depends" }, { "package": "stats", "role": "Imports" }, { "package": "dplyr", "role": "Imports" }, { "package": "rlang", "role": "Imports" }, { "package": "knitr", "role": "Suggests" }, { "package": "rmarkdown", "role": "Suggests" }, { "package": "xfun", "role": "Suggests" }, { "package": "DT", "role": "Suggests" } ], "_owner": "cran", "_selfowned": false, "_usedby": 0, "_updates": [ { "week": "2026-26", "n": 1 } ], "_tags": [ { "name": "1.0.0", "date": "2026-06-23" } ], "_stars": 0, "_contributors": [ { "user": "noemimontobbio", "count": 1, "uuid": 94608349 } ], "_userbio": { "uuid": 6899542, "type": "organization", "name": "cran", "followers": 610, "description": "Unofficial read-only mirror of all CRAN R packages" }, "_downloads": { "count": 0, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/msprog" }, "_searchresults": 23, "_rbuild": "4.6.0", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/msprog.html", "LICENSE", "manual.pdf" ], "_cranurl": false, "_releases": [ { "version": "1.0.0", "date": "2026-06-23" } ], "_exports": [ "compute_delta", "is_event", "MSprog", "relapse_indep_from_bounds", "value_milestone" ], "_datasets": [ { "name": "toydata_relapses", "title": "Synthetic Relapse Data", "object": "toydata_relapses", "class": [ "tbl_df", "tbl", "data.frame" ], "fields": [ "id", "date", "visit_day" ], "rows": 5, "table": true, "tojson": true }, { "name": "toydata_visits", "title": "Synthetic Longitudinal EDSS and SDMT Data", "object": "toydata_visits", "class": [ "tbl_df", "tbl", "data.frame" ], "fields": [ "id", "date", "visit_day", "EDSS", "SDMT" ], "rows": 57, "table": true, "tojson": true } ], "_help": [ { "page": "compute_delta", "title": "Default minimum clinically meaningful shift for different scales.", "topics": [ "compute_delta" ] }, { "page": "is_event", "title": "Compare value to reference.", "topics": [ "is_event" ] }, { "page": "MSprog", "title": "Assess multiple sclerosis disability course from longitudinal data.", "topics": [ "MSprog" ] }, { "page": "print.MSprogOutput", "title": "Textual description of criteria used to assess disability course.", "topics": [ "print.MSprogOutput" ] }, { "page": "relapse_indep_from_bounds", "title": "Define relapse-free intervals for PIRA definition.", "topics": [ "relapse_indep_from_bounds" ] }, { "page": "toydata_relapses", "title": "Synthetic Relapse Data", "topics": [ "toydata_relapses" ] }, { "page": "toydata_visits", "title": "Synthetic Longitudinal EDSS and SDMT Data", "topics": [ "toydata_visits" ] }, { "page": "value_milestone", "title": "Time to disability milestone.", "topics": [ "value_milestone" ] } ], "_rundeps": [ "cli", "dplyr", "generics", "glue", "lifecycle", "magrittr", "pillar", "pkgconfig", "R6", "rlang", "tibble", "tidyselect", "utf8", "vctrs", "withr" ], "_vignettes": [ { "source": "vignette0.Rmd", "filename": "vignette0.html", "title": "Analysing disability course in MS", "author": "Noemi Montobbio", "engine": "knitr::rmarkdown", "headings": [ "Input data", "Minimal example", "Outcome", "Customising \"clinically relevant change\"", "Baseline scheme", "Additional options", "Multiple events", "Event confirmation", "Sustained CDW or CDI", "Relapse-based classification of CDW events", "Relapse-associated worsening (RAW)", "Progression independent of relapse activity (PIRA)", "MSprog() outputs", "What to include in results", "Printing progress info", "Time to disability milestone", "References" ], "created": "2026-06-23 16:00:02", "modified": "2026-06-23 16:00:02", "commits": 1 }, { "source": "vignette_PIRA.Rmd", "filename": "vignette_PIRA.html", "title": "Assessing progression independent of relapse activity (PIRA) in MS", "author": "Noemi Montobbio", "engine": "knitr::rmarkdown", "headings": [ "Defining PIRA", "Detecting PIRA", "References" ], "created": "2026-06-23 16:00:02", "modified": "2026-06-23 16:00:02", "commits": 1 }, { "source": "vignette_time2event.Rmd", "filename": "vignette_time2event.html", "title": "Time to event", "author": "Noemi Montobbio", "engine": "knitr::rmarkdown", "headings": [ "Time to first disability worsening event", "Time to disability milestone", "Multiple events" ], "created": "2026-06-23 16:00:02", "modified": "2026-06-23 16:00:02", "commits": 1 } ], "_score": 2.838849090737255, "_indexed": true, "_nocasepkg": "msprog", "_universes": [ "cran", "noemimontobbio" ], "_binaries": [ { "r": "4.7.0", "os": "linux", "version": "1.0.0", "date": "2026-06-23T19:18:44.000Z", "distro": "resolute", "commit": "82e9caff29d0133b158a2c2e7cfbebe9ffdbc5da", "fileid": "ce8ce82d4bc58d2236509877de78114f72b729198b6590a3834a32efa2c8c0d1", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/cran/actions/runs/28050578151" }, { "r": "4.6.0", "os": "linux", "version": "1.0.0", "date": "2026-06-23T19:18:35.000Z", "distro": "resolute", "commit": "82e9caff29d0133b158a2c2e7cfbebe9ffdbc5da", "fileid": "237f2f2ea32bd6050b121a63bf5bdff6235727e57c98e3dae4bfa33c1a1d0d27", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/cran/actions/runs/28050578151" }, { "r": "4.6.0", "os": "wasm", "version": "1.0.0", "date": "2026-06-23T19:19:30.000Z", "commit": "82e9caff29d0133b158a2c2e7cfbebe9ffdbc5da", "fileid": "6567c19b74b4781952375ba10c2ddb227554b629fd470a7f656ac0535ece503f", "status": "success", "buildurl": "https://github.com/r-universe/cran/actions/runs/28050578151" } ] }