{
  "_id": "6abb977b99f7aa8c6aa467bb",
  "Package": "msce",
  "Type": "Package",
  "Title": "Hazard of Multi-Stage Clonal Expansion Models",
  "Version": "1.0.2",
  "Date": "2025-12-05",
  "Authors@R": "c(person(given = \"Cristoforo\",\nfamily = \"Simonetto\",\nrole = c(\"aut\", \"cre\"),\nemail = \"cristoforo.simonetto@ph.tum.de\",\ncomment = c(ORCID = \"0000-0003-4816-3514\")),\nperson(given = c(\"Jan\", \"Christian\"),\nfamily = \"Kaiser\",\nrole = \"ctb\"))",
  "Author": "Cristoforo Simonetto [aut, cre] (ORCID:\n<https://orcid.org/0000-0003-4816-3514>), Jan Christian Kaiser\n[ctb]",
  "Maintainer": "Cristoforo Simonetto <cristoforo.simonetto@ph.tum.de>",
  "Description": "Functions to calculate hazard and survival function of\nMulti-Stage Clonal Expansion Models used in cancer\nepidemiology. For the Two-Stage Clonal Expansion Model an exact\nsolution is implemented assuming piecewise constant parameters,\nsee Heidenreich, Luebeck, Moolgavkar (1997)\n<doi:10.1111/j.1539-6924.1997.tb00878.x>. Numerical solutions\nare provided for its extensions, see also Little, Vineis, Li\n(2008) <doi:10.1016/j.jtbi.2008.05.027>.",
  "License": "GPL (>= 2)",
  "Encoding": "UTF-8",
  "RoxygenNote": "7.3.3",
  "VignetteBuilder": "knitr",
  "NeedsCompilation": "yes",
  "Packaged": {
    "Date": "2026-09-29 10:44:08 UTC",
    "User": "root"
  },
  "Repository": "https://cran.r-universe.dev",
  "Date/Publication": "2025-12-17 02:21:06 UTC",
  "RemoteUrl": "https://github.com/cran/msce",
  "RemoteRef": "HEAD",
  "RemoteSha": "826601c801598234a155928326e8c47bc28badf1",
  "_user": "cran",
  "_type": "src",
  "_file": "msce_1.0.2.tar.gz",
  "_fileid": "https://r2.ropensci.org/db42da167c4d0709f32ac57c51ae7fffea49215e0ffc31e6d181eda521113a40",
  "_filesize": 327716,
  "_sha256": "db42da167c4d0709f32ac57c51ae7fffea49215e0ffc31e6d181eda521113a40",
  "_expires": "2027-01-07T10:48:25.000Z",
  "_created": "2026-09-29T10:44:08.000Z",
  "_published": "2026-09-29T10:48:27.111Z",
  "_jobs": [
    {
      "job": 109369875341,
      "time": 126,
      "config": "linux-devel-arm64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11028735568"
    },
    {
      "job": 109369875195,
      "time": 140,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11027954917"
    },
    {
      "job": 109369875295,
      "time": 117,
      "config": "linux-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11027269903"
    },
    {
      "job": 109369875374,
      "time": 139,
      "config": "linux-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11028450257"
    },
    {
      "job": 109368714775,
      "time": 202,
      "config": "source",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11027539640"
    },
    {
      "job": 109369875102,
      "time": 133,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "11028270515"
    },
    {
      "job": 109369875471,
      "time": 212,
      "config": "windows-devel-arm64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11028365459"
    },
    {
      "job": 109369875765,
      "time": 155,
      "config": "windows-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11028495241"
    },
    {
      "job": 109369875350,
      "time": 211,
      "config": "windows-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11028390498"
    },
    {
      "job": 109369875237,
      "time": 98,
      "config": "windows-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11028545173"
    }
  ],
  "_host": "GitHub-Actions",
  "_buildurl": "https://github.com/r-universe/cran/actions/runs/36557041121",
  "_status": "success",
  "_upstream": "https://github.com/cran/msce",
  "_commit": {
    "id": "826601c801598234a155928326e8c47bc28badf1",
    "author": "Cristoforo Simonetto <cristoforo.simonetto@ph.tum.de>",
    "committer": "cran-robot <csardi.gabor+cran@gmail.com>",
    "message": "version 1.0.2\n",
    "time": 1765938066
  },
  "_maintainer": {
    "name": "Cristoforo Simonetto",
    "email": "cristoforo.simonetto@ph.tum.de",
    "orcid": "0000-0003-4816-3514"
  },
  "_distro": "resolute",
  "_registered": true,
  "_dependencies": [
    {
      "package": "Rcpp",
      "role": "LinkingTo"
    },
    {
      "package": "RcppParallel",
      "role": "LinkingTo"
    },
    {
      "package": "Rcpp",
      "version": ">= 1.0.3",
      "role": "Imports"
    },
    {
      "package": "RcppParallel",
      "version": ">= 5.0.0",
      "role": "Imports"
    },
    {
      "package": "knitr",
      "role": "Suggests"
    },
    {
      "package": "rmarkdown",
      "role": "Suggests"
    },
    {
      "package": "testthat",
      "role": "Suggests"
    }
  ],
  "_owner": "cran",
  "_selfowned": false,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2025-51",
      "n": 1
    }
  ],
  "_tags": [
    {
      "name": "1.0.2",
      "date": "2025-12-17"
    }
  ],
  "_stars": 0,
  "_contributors": [
    {
      "user": "cristoforosimonetto",
      "count": 1,
      "uuid": 87534109
    }
  ],
  "_userbio": {
    "uuid": 6899542,
    "type": "organization",
    "name": "cran",
    "followers": 630,
    "description": "Unofficial read-only mirror of all CRAN R packages"
  },
  "_downloads": {
    "count": 328,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/msce"
  },
  "_searchresults": 0,
  "_topics": [
    "cpp"
  ],
  "_rbuild": "4.6.1",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/manual.pdf",
    "extra/msce.html"
  ],
  "_realowner": "cran",
  "_cranurl": false,
  "_releases": [
    {
      "version": "1.0.1",
      "date": "2020-10-29"
    },
    {
      "version": "1.0.2",
      "date": "2025-12-17"
    }
  ],
  "_exports": [
    "msce_numerical",
    "tsce"
  ],
  "_datasets": [
    {
      "name": "lungCancerRadon",
      "title": "Exemplary person year table",
      "object": "lungCancerRadon",
      "file": "lungCancerRadon.rda",
      "class": [
        "data.frame"
      ],
      "fields": [
        "doseRate",
        "ageBeginExposure",
        "ageEndExposure",
        "isCase",
        "ageEndFollowUp"
      ],
      "rows": 4260,
      "table": true,
      "tojson": true
    },
    {
      "name": "lungCancerSmoking",
      "title": "Exemplary person year table",
      "object": "lungCancerSmoking",
      "file": "lungCancerSmoking.rda",
      "class": [
        "data.frame"
      ],
      "fields": [
        "age",
        "ageStart",
        "ageQuit",
        "cigsPerDay",
        "pyr",
        "cases"
      ],
      "rows": 1368,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "lungCancerRadon",
      "title": "Exemplary person year table",
      "topics": [
        "lungCancerRadon"
      ]
    },
    {
      "page": "lungCancerSmoking",
      "title": "Exemplary person year table",
      "topics": [
        "lungCancerSmoking"
      ]
    },
    {
      "page": "msce_numerical",
      "title": "Numerical solution of the Multi-Stage Clonal Expansion Model",
      "topics": [
        "msce_numerical"
      ]
    },
    {
      "page": "tsce",
      "title": "Exact solution of the Two-Stage Clonal Expansion Model",
      "topics": [
        "tsce"
      ]
    }
  ],
  "_rundeps": [
    "Rcpp",
    "RcppParallel"
  ],
  "_sysdeps": [
    {
      "shlib": "libstdc++",
      "package": "libstdc++6",
      "source": "gcc",
      "version": "16-20260322-1ubuntu1",
      "name": "c++",
      "homepage": "http://gcc.gnu.org/",
      "description": "GNU Standard C++ Library v3"
    }
  ],
  "_vignettes": [
    {
      "source": "msce.Rmd",
      "filename": "msce.html",
      "title": "Fitting Incidence Data with Multi-Stage Clonal Expansion Models using msce",
      "author": "Cristoforo Simonetto",
      "engine": "knitr::rmarkdown",
      "headings": [
        "Motivation",
        "A glimpse on Multi-Stage Clonal Expansion Models",
        "General cautions on fitting incidence data with Multi-Stage Clonal Expansion Models",
        "A fitting approach",
        "References"
      ],
      "created": "2020-10-29 14:10:02",
      "modified": "2025-12-17 02:21:06",
      "commits": 2
    }
  ],
  "_score": 2,
  "_indexed": true,
  "_nocasepkg": "msce",
  "_universes": [
    "cran"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.0.2",
      "date": "2026-09-29T10:46:19.000Z",
      "distro": "resolute",
      "arch": "aarch64",
      "commit": "826601c801598234a155928326e8c47bc28badf1",
      "fileid": "https://r2.ropensci.org/592cea9e3da6b93765e1ba72bd3916f2b26c4d4ddefd9a78ef5d52aa66ba9667",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/cran/actions/runs/36557041121"
    },
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.0.2",
      "date": "2026-09-29T10:46:27.000Z",
      "distro": "resolute",
      "arch": "x86_64",
      "commit": "826601c801598234a155928326e8c47bc28badf1",
      "fileid": "https://r2.ropensci.org/e23a125a3169dbd570c8dae24c161fcdc28264ec981cef29342047bea0b6db8a",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/cran/actions/runs/36557041121"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "1.0.2",
      "date": "2026-09-29T10:46:14.000Z",
      "distro": "resolute",
      "arch": "aarch64",
      "commit": "826601c801598234a155928326e8c47bc28badf1",
      "fileid": "https://r2.ropensci.org/d4343e632a0f4b84a06663b680c519b018d70465a326fc174c33eb2865f111ff",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/cran/actions/runs/36557041121"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "1.0.2",
      "date": "2026-09-29T10:46:28.000Z",
      "distro": "resolute",
      "arch": "x86_64",
      "commit": "826601c801598234a155928326e8c47bc28badf1",
      "fileid": "https://r2.ropensci.org/d46399f51b965c73bf0c5ea815b8b91288af530b91b1269ec670a24cbbab1eae",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/cran/actions/runs/36557041121"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.0.2",
      "date": "2026-09-29T10:46:38.000Z",
      "arch": "emscripten",
      "commit": "826601c801598234a155928326e8c47bc28badf1",
      "fileid": "https://r2.ropensci.org/eb868afd5137260e934cce0cafd8751dfc6524df839b3735bfb877356bbc8ede",
      "status": "success",
      "buildurl": "https://github.com/r-universe/cran/actions/runs/36557041121"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.0.2",
      "date": "2026-09-29T10:47:30.000Z",
      "arch": "aarch64",
      "commit": "826601c801598234a155928326e8c47bc28badf1",
      "fileid": "https://r2.ropensci.org/015cef3de4e741a6041ef5ebb17ddf41533f3b0b7f5c46a5247d196a1507cdf5",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/cran/actions/runs/36557041121"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.0.2",
      "date": "2026-09-29T10:45:38.000Z",
      "arch": "x86_64",
      "commit": "826601c801598234a155928326e8c47bc28badf1",
      "fileid": "https://r2.ropensci.org/35b41ae5214c215aec3d6b1643e0f0b3a52213393226401c6cd533b2ffa7995a",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/cran/actions/runs/36557041121"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "1.0.2",
      "date": "2026-09-29T10:47:29.000Z",
      "arch": "aarch64",
      "commit": "826601c801598234a155928326e8c47bc28badf1",
      "fileid": "https://r2.ropensci.org/3621d52c80dfe665104394532d8de4150d23481eba337c8a8b1ee8f204167f67",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/cran/actions/runs/36557041121"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "1.0.2",
      "date": "2026-09-29T10:45:27.000Z",
      "arch": "x86_64",
      "commit": "826601c801598234a155928326e8c47bc28badf1",
      "fileid": "https://r2.ropensci.org/d89f71e808c7fb5c86ed96b0f23f5b1d95a4556ec8e5945fcfef2e461f123569",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/cran/actions/runs/36557041121"
    }
  ]
}