{
  "_id": "6a1e85b71d7bb097a0a67119",
  "Package": "drc",
  "Version": "3.0-1",
  "Date": "2016-08-25",
  "Title": "Analysis of Dose-Response Curves",
  "Author": "Christian Ritz <ritz@bioassay.dk>, Jens C. Strebig\n<streibig@bioassay.dk>",
  "Maintainer": "Christian Ritz <ritz@bioassay.dk>",
  "LazyLoad": "yes",
  "LazyData": "yes",
  "Description": "Analysis of dose-response data is made available through a\nsuite of flexible and versatile model fitting and after-fitting\nfunctions.",
  "License": "GPL-2 | file LICENCE",
  "URL": "http://www.r-project.org, http://www.bioassay.dk",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-06-02 07:22:56 UTC",
    "User": "root"
  },
  "Repository": "https://cran.r-universe.dev",
  "Date/Publication": "2016-08-30 01:33:38 UTC",
  "RemoteUrl": "https://github.com/cran/drc",
  "RemoteRef": "HEAD",
  "RemoteSha": "ad2974183da72a4978467f77615d3d41eb4026a5",
  "MD5sum": "833fe2d8aeae1d14fca5141b3d4e8c18",
  "_user": "cran",
  "_type": "src",
  "_file": "drc_3.0-1.tar.gz",
  "_fileid": "5a0777ce2f2fc4dfd1ed48c21860355319644ce87d4170f418a12569f8d1020b",
  "_filesize": 770841,
  "_sha256": "5a0777ce2f2fc4dfd1ed48c21860355319644ce87d4170f418a12569f8d1020b",
  "_created": "2026-06-02T07:22:56.000Z",
  "_published": "2026-06-02T07:26:47.079Z",
  "_distro": "noble",
  "_jobs": [
    {
      "job": 79019981058,
      "time": 162,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "NOTE",
      "artifact": "7351459913"
    },
    {
      "job": 79019981046,
      "time": 179,
      "config": "linux-release-x86_64",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7351465290"
    },
    {
      "job": 79019456478,
      "time": 212,
      "config": "source",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7351411387"
    },
    {
      "job": 79019981010,
      "time": 114,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7351445547"
    }
  ],
  "_buildurl": "https://github.com/r-universe/cran/actions/runs/26804601575",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_upstream": "https://github.com/cran/drc",
  "_commit": {
    "id": "ad2974183da72a4978467f77615d3d41eb4026a5",
    "author": "Christian Ritz <ritz@bioassay.dk>",
    "committer": "cran-robot <csardi.gabor+cran@gmail.com>",
    "message": "version 3.0-1\n",
    "time": 1472520818
  },
  "_maintainer": {
    "name": "Christian Ritz",
    "email": "ritz@bioassay.dk"
  },
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 2.0.0",
      "role": "Depends"
    },
    {
      "package": "MASS",
      "role": "Depends"
    },
    {
      "package": "stats",
      "role": "Depends"
    },
    {
      "package": "car",
      "role": "Imports"
    },
    {
      "package": "gtools",
      "role": "Imports"
    },
    {
      "package": "multcomp",
      "role": "Imports"
    },
    {
      "package": "plotrix",
      "role": "Imports"
    },
    {
      "package": "scales",
      "role": "Imports"
    }
  ],
  "_owner": "cran",
  "_selfowned": false,
  "_usedby": 30,
  "_updates": [],
  "_tags": [],
  "_stars": 8,
  "_userbio": {
    "uuid": 6899542,
    "type": "organization",
    "name": "cran",
    "description": "Unofficial read-only mirror of all CRAN R packages"
  },
  "_downloads": {
    "count": 86904,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/drc"
  },
  "_mentions": 291,
  "_searchresults": 1408,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/drc.html",
    "extra/NEWS.html",
    "extra/NEWS.txt",
    "manual.pdf"
  ],
  "_realowner": "cran",
  "_cranurl": false,
  "_releases": [
    {
      "version": "0.8-2",
      "date": "2005-12-14"
    },
    {
      "version": "0.9-0",
      "date": "2006-02-08"
    },
    {
      "version": "1.0-3",
      "date": "2006-10-08"
    },
    {
      "version": "1.1-0",
      "date": "2007-02-01"
    },
    {
      "version": "1.2-0",
      "date": "2007-05-14"
    },
    {
      "version": "1.3-0",
      "date": "2007-09-24"
    },
    {
      "version": "1.4-2",
      "date": "2008-05-06"
    },
    {
      "version": "1.4-7",
      "date": "2008-09-18"
    },
    {
      "version": "1.5-0",
      "date": "2008-11-04"
    },
    {
      "version": "1.5-1",
      "date": "2008-11-10"
    },
    {
      "version": "1.5-2",
      "date": "2008-11-13"
    },
    {
      "version": "1.5-5",
      "date": "2009-02-08"
    },
    {
      "version": "1.6-0",
      "date": "2009-03-24"
    },
    {
      "version": "1.6-1",
      "date": "2009-03-25"
    },
    {
      "version": "1.6-3",
      "date": "2009-04-14"
    },
    {
      "version": "1.7-0",
      "date": "2009-06-08"
    },
    {
      "version": "1.7-2",
      "date": "2009-07-18"
    },
    {
      "version": "1.7-7",
      "date": "2009-09-03"
    },
    {
      "version": "1.8-1",
      "date": "2010-01-12"
    },
    {
      "version": "1.9-0",
      "date": "2010-04-23"
    },
    {
      "version": "1.9-1",
      "date": "2010-05-03"
    },
    {
      "version": "1.9-3",
      "date": "2010-05-31"
    },
    {
      "version": "2.0-1",
      "date": "2010-09-23"
    },
    {
      "version": "2.1-1",
      "date": "2011-03-10"
    },
    {
      "version": "2.1-4",
      "date": "2011-04-10"
    },
    {
      "version": "2.2-1",
      "date": "2011-09-20"
    },
    {
      "version": "2.2-9",
      "date": "2012-06-10"
    },
    {
      "version": "2.3-0",
      "date": "2012-06-22"
    },
    {
      "version": "2.3-7",
      "date": "2013-04-18"
    },
    {
      "version": "2.3-96",
      "date": "2013-11-29"
    },
    {
      "version": "2.5-11",
      "date": "2015-04-13"
    },
    {
      "version": "2.5-12",
      "date": "2015-04-14"
    },
    {
      "version": "3.0-1",
      "date": "2016-08-29"
    }
  ],
  "_exports": [
    "AR.2",
    "AR.3",
    "backfit",
    "baro5",
    "BC.4",
    "BC.5",
    "bcl3",
    "bcl4",
    "braincousens",
    "bread.drc",
    "cedergreen",
    "CIcomp",
    "CIcompX",
    "comped",
    "compParm",
    "CRS.4a",
    "CRS.4b",
    "CRS.4c",
    "CRS.5a",
    "CRS.5b",
    "CRS.5c",
    "CRS.6",
    "drm",
    "drmc",
    "ED",
    "EDcomp",
    "estfun.drc",
    "EXD.2",
    "EXD.3",
    "FPL.4",
    "fplogistic",
    "G.2",
    "G.3",
    "G.3u",
    "G.4",
    "gammadr",
    "gaussian",
    "getInitial",
    "getMeanFunctions",
    "gompertz",
    "gompertzd",
    "isobole",
    "L.3",
    "L.4",
    "L.5",
    "l2",
    "l3",
    "l3u",
    "l4",
    "l5",
    "lgaussian",
    "lin.test",
    "LL.2",
    "LL.3",
    "LL.3u",
    "LL.4",
    "LL.5",
    "LL2.2",
    "LL2.3",
    "LL2.3u",
    "LL2.4",
    "LL2.5",
    "llogistic",
    "llogistic2",
    "LN.2",
    "LN.3",
    "LN.3u",
    "LN.4",
    "lnormal",
    "logistic",
    "maED",
    "MAX",
    "mixture",
    "ml3a",
    "ml3b",
    "ml3c",
    "ml4a",
    "ml4b",
    "ml4c",
    "MM.2",
    "MM.3",
    "modelFit",
    "mr.test",
    "mselect",
    "multi2",
    "NEC.2",
    "NEC.3",
    "NEC.4",
    "neill.test",
    "noEffect",
    "plotFACI",
    "PR",
    "rdrm",
    "relpot",
    "searchdrc",
    "simDR",
    "twophase",
    "ucedergreen",
    "UCRS.4a",
    "UCRS.4b",
    "UCRS.4c",
    "UCRS.5a",
    "UCRS.5b",
    "UCRS.5c",
    "uml3a",
    "uml3b",
    "uml3c",
    "uml4a",
    "uml4b",
    "uml4c",
    "ursa",
    "W1.2",
    "W1.3",
    "W1.3u",
    "W1.4",
    "w2",
    "W2.2",
    "W2.3",
    "W2.3u",
    "W2.4",
    "W2x.3",
    "W2x.4",
    "w3",
    "w4",
    "weibull1",
    "weibull2",
    "weibull2x",
    "yieldLoss"
  ],
  "_datasets": [
    {
      "name": "acidiq",
      "title": "Acifluorfen and diquat tested on Lemna minor.",
      "object": "acidiq",
      "class": [
        "data.frame"
      ],
      "fields": [
        "dose",
        "pct",
        "rgr"
      ],
      "rows": 180,
      "table": true,
      "tojson": true
    },
    {
      "name": "algae",
      "title": "Volume of algae as function of increasing concentrations of a herbicide",
      "object": "algae",
      "class": [
        "data.frame"
      ],
      "fields": [
        "conc",
        "vol"
      ],
      "rows": 14,
      "table": true,
      "tojson": true
    },
    {
      "name": "auxins",
      "title": "Effect of technical grade and commercially formulated auxin herbicides",
      "object": "auxins",
      "class": [
        "data.frame"
      ],
      "fields": [
        "r",
        "h",
        "w",
        "y",
        "dose"
      ],
      "rows": 150,
      "table": true,
      "tojson": true
    },
    {
      "name": "chickweed",
      "title": "Germination of common chickweed (_Stellaria media_)",
      "object": "chickweed",
      "class": [
        "data.frame"
      ],
      "fields": [
        "start",
        "end",
        "count"
      ],
      "rows": 35,
      "table": true,
      "tojson": true
    },
    {
      "name": "chickweed0",
      "title": "Germination of common chickweed (_Stellaria media_)",
      "object": "chickweed0",
      "class": [
        "data.frame"
      ],
      "fields": [
        "time",
        "count"
      ],
      "rows": 34,
      "table": true,
      "tojson": true
    },
    {
      "name": "daphnids",
      "title": "Daphnia test",
      "object": "daphnids",
      "class": [
        "data.frame"
      ],
      "fields": [
        "dose",
        "no",
        "total",
        "time"
      ],
      "rows": 16,
      "table": true,
      "tojson": true
    },
    {
      "name": "decontaminants",
      "title": "Performance of decontaminants used in the culturing of a micro-organism",
      "object": "decontaminants",
      "class": [
        "data.frame"
      ],
      "fields": [
        "conc",
        "count",
        "group"
      ],
      "rows": 128,
      "table": true,
      "tojson": true
    },
    {
      "name": "deguelin",
      "title": "Deguelin applied to chrysanthemum aphis",
      "object": "deguelin",
      "class": [
        "data.frame"
      ],
      "fields": [
        "dose",
        "log10dose",
        "r",
        "n"
      ],
      "rows": 6,
      "table": true,
      "tojson": true
    },
    {
      "name": "earthworms",
      "title": "Earthworm toxicity test",
      "object": "earthworms",
      "class": [
        "data.frame"
      ],
      "fields": [
        "dose",
        "number",
        "total"
      ],
      "rows": 35,
      "table": true,
      "tojson": true
    },
    {
      "name": "etmotc",
      "title": "Effect of erythromycin on mixed sewage microorganisms",
      "object": "etmotc",
      "class": [
        "data.frame"
      ],
      "fields": [
        "cell",
        "dose1",
        "pct1",
        "rgr1"
      ],
      "rows": 57,
      "table": true,
      "tojson": true
    },
    {
      "name": "finney71",
      "title": "Example from Finney (1971)",
      "object": "finney71",
      "class": [
        "data.frame"
      ],
      "fields": [
        "dose",
        "total",
        "affected"
      ],
      "rows": 6,
      "table": true,
      "tojson": true
    },
    {
      "name": "G.aparine",
      "title": "Herbicide applied to Galium aparine",
      "object": "G.aparine",
      "class": [
        "data.frame"
      ],
      "fields": [
        "dose",
        "drymatter",
        "treatment"
      ],
      "rows": 240,
      "table": true,
      "tojson": true
    },
    {
      "name": "germination",
      "title": "Germination of three crops",
      "object": "germination",
      "class": [
        "data.frame"
      ],
      "fields": [
        "temp",
        "species",
        "start",
        "end",
        "germinated"
      ],
      "rows": 192,
      "table": true,
      "tojson": true
    },
    {
      "name": "glymet",
      "title": "Glyphosate and metsulfuron-methyl tested on algae.",
      "object": "glymet",
      "class": [
        "data.frame"
      ],
      "fields": [
        "dose",
        "pct",
        "rgr"
      ],
      "rows": 113,
      "table": true,
      "tojson": true
    },
    {
      "name": "H.virescens",
      "title": "Mortality of tobacco budworms",
      "object": "H.virescens",
      "class": [
        "data.frame"
      ],
      "fields": [
        "dose",
        "numdead",
        "total",
        "sex"
      ],
      "rows": 12,
      "table": true,
      "tojson": true
    },
    {
      "name": "heartrate",
      "title": "Heart rate baroreflexes for rabbits",
      "object": "heartrate",
      "class": [
        "data.frame"
      ],
      "fields": [
        "pressure",
        "rate"
      ],
      "rows": 18,
      "table": true,
      "tojson": true
    },
    {
      "name": "leaflength",
      "title": "Leaf length of barley",
      "object": "leaflength",
      "class": [
        "data.frame"
      ],
      "fields": [
        "Dose",
        "DW"
      ],
      "rows": 42,
      "table": true,
      "tojson": true
    },
    {
      "name": "lepidium",
      "title": "Dose-response profile of degradation of agrochemical using lepidium",
      "object": "lepidium",
      "class": [
        "data.frame"
      ],
      "fields": [
        "conc",
        "weight"
      ],
      "rows": 42,
      "table": true,
      "tojson": true
    },
    {
      "name": "lettuce",
      "title": "Hormesis in lettuce plants",
      "object": "lettuce",
      "class": [
        "data.frame"
      ],
      "fields": [
        "conc",
        "weight"
      ],
      "rows": 14,
      "table": true,
      "tojson": true
    },
    {
      "name": "M.bahia",
      "title": "Effect of an effluent on the growth of mysid shrimp",
      "object": "M.bahia",
      "class": [
        "data.frame"
      ],
      "fields": [
        "conc",
        "dryweight"
      ],
      "rows": 40,
      "table": true,
      "tojson": true
    },
    {
      "name": "mecter",
      "title": "Mechlorprop and terbythylazine tested on Lemna minor",
      "object": "mecter",
      "class": [
        "data.frame"
      ],
      "fields": [
        "dose",
        "pct",
        "rgr"
      ],
      "rows": 102,
      "table": true,
      "tojson": true
    },
    {
      "name": "metals",
      "title": "Data from heavy metal mixture experiments",
      "object": "metals",
      "class": [
        "data.frame"
      ],
      "fields": [
        "metal",
        "conc",
        "BIF"
      ],
      "rows": 543,
      "table": true,
      "tojson": true
    },
    {
      "name": "methionine",
      "title": "Weight gain for different methionine sources",
      "object": "methionine",
      "class": [
        "data.frame"
      ],
      "fields": [
        "product",
        "dose",
        "gain"
      ],
      "rows": 9,
      "table": true,
      "tojson": true
    },
    {
      "name": "nasturtium",
      "title": "Dose-response profile of degradation of agrochemical using nasturtium",
      "object": "nasturtium",
      "class": [
        "data.frame"
      ],
      "fields": [
        "conc",
        "weight"
      ],
      "rows": 42,
      "table": true,
      "tojson": true
    },
    {
      "name": "O.mykiss",
      "title": "Test data from a 21 day fish test",
      "object": "O.mykiss",
      "class": [
        "data.frame"
      ],
      "fields": [
        "conc",
        "weight"
      ],
      "rows": 70,
      "table": true,
      "tojson": true
    },
    {
      "name": "P.promelas",
      "title": "Effect of sodium pentachlorophenate on growth of fathead minnow",
      "object": "P.promelas",
      "class": [
        "data.frame"
      ],
      "fields": [
        "conc",
        "dryweight"
      ],
      "rows": 24,
      "table": true,
      "tojson": true
    },
    {
      "name": "RScompetition",
      "title": "Competition between two biotypes",
      "object": "RScompetition",
      "class": [
        "data.frame"
      ],
      "fields": [
        "z",
        "x",
        "biomass"
      ],
      "rows": 49,
      "table": true,
      "tojson": true
    },
    {
      "name": "ryegrass",
      "title": "Effect of ferulic acid on growth of ryegrass",
      "object": "ryegrass",
      "class": [
        "data.frame"
      ],
      "fields": [
        "rootl",
        "conc"
      ],
      "rows": 24,
      "table": true,
      "tojson": true
    },
    {
      "name": "S.alba",
      "title": "Potency of two herbicides",
      "object": "S.alba",
      "class": [
        "data.frame"
      ],
      "fields": [
        "Dose",
        "Herbicide",
        "DryMatter"
      ],
      "rows": 68,
      "table": true,
      "tojson": true
    },
    {
      "name": "S.capricornutum",
      "title": "Effect of cadmium on growth of green alga",
      "object": "S.capricornutum",
      "class": [
        "data.frame"
      ],
      "fields": [
        "conc",
        "count"
      ],
      "rows": 18,
      "table": true,
      "tojson": true
    },
    {
      "name": "secalonic",
      "title": "Root length measurements",
      "object": "secalonic",
      "class": [
        "data.frame"
      ],
      "fields": [
        "dose",
        "rootl"
      ],
      "rows": 7,
      "table": true,
      "tojson": true
    },
    {
      "name": "selenium",
      "title": "Data from toxicology experiments with selenium",
      "object": "selenium",
      "class": [
        "data.frame"
      ],
      "fields": [
        "type",
        "conc",
        "total",
        "dead"
      ],
      "rows": 25,
      "table": true,
      "tojson": true
    },
    {
      "name": "spinach",
      "title": "Inhibition of photosynthesis",
      "object": "spinach",
      "class": [
        "data.frame"
      ],
      "fields": [
        "CURVE",
        "HERBICIDE",
        "DOSE",
        "SLOPE"
      ],
      "rows": 105,
      "table": true,
      "tojson": true
    },
    {
      "name": "terbuthylazin",
      "title": "The effect of terbuthylazin on growth rate",
      "object": "terbuthylazin",
      "class": [
        "data.frame"
      ],
      "fields": [
        "dose",
        "rgr"
      ],
      "rows": 30,
      "table": true,
      "tojson": true
    },
    {
      "name": "vinclozolin",
      "title": "Vinclozolin from AR in vitro assay",
      "object": "vinclozolin",
      "class": [
        "data.frame"
      ],
      "fields": [
        "exper",
        "conc",
        "effect"
      ],
      "rows": 53,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "acidiq",
      "title": "Acifluorfen and diquat tested on Lemna minor.",
      "topics": [
        "acidiq"
      ]
    },
    {
      "page": "algae",
      "title": "Volume of algae as function of increasing concentrations of a herbicide",
      "topics": [
        "algae"
      ]
    },
    {
      "page": "anova.drc",
      "title": "ANOVA for dose-response model fits",
      "concept": [
        "extra sum-of-squares F-test",
        "approximate F-test"
      ],
      "topics": [
        "anova.drc"
      ]
    },
    {
      "page": "AR",
      "title": "Asymptotic regression model",
      "topics": [
        "AR.2",
        "AR.3"
      ]
    },
    {
      "page": "auxins",
      "title": "Effect of technical grade and commercially formulated auxin herbicides",
      "topics": [
        "auxins"
      ]
    },
    {
      "page": "backfit",
      "title": "Calculation of backfit values from a fitted dose-response model",
      "topics": [
        "backfit"
      ]
    },
    {
      "page": "baro5",
      "title": "The modified baro5 function",
      "topics": [
        "baro5"
      ]
    },
    {
      "page": "BC",
      "title": "The Brain-Cousens hormesis models",
      "topics": [
        "BC.4",
        "BC.5",
        "bcl3",
        "bcl4"
      ]
    },
    {
      "page": "boxcox.drc",
      "title": "Transform-both-sides Box-Cox transformation",
      "topics": [
        "boxcox.drc"
      ]
    },
    {
      "page": "braincousens",
      "title": "The Brain-Cousens hormesis models",
      "concept": [
        "hormesis hormetic effect initial stimulation"
      ],
      "topics": [
        "braincousens"
      ]
    },
    {
      "page": "bread.drc",
      "title": "Bread and meat for the sandwich",
      "topics": [
        "bread.drc",
        "estfun.drc"
      ]
    },
    {
      "page": "cedergreen",
      "title": "The Cedergreen-Ritz-Streibig model",
      "concept": [
        "hormesis hormetic effect initial stimulation u-shaped"
      ],
      "topics": [
        "cedergreen",
        "CRS.6",
        "ucedergreen"
      ]
    },
    {
      "page": "chickweed",
      "title": "Germination of common chickweed (_Stellaria media_)",
      "topics": [
        "chickweed",
        "chickweed0"
      ]
    },
    {
      "page": "CIcompX",
      "title": "Calculation of combination index for binary mixtures",
      "concept": [
        "antagonism mixture synergy"
      ],
      "topics": [
        "CIcomp",
        "CIcompX",
        "plotFACI"
      ]
    },
    {
      "page": "coef.drc",
      "title": "Extract Model Coefficients",
      "topics": [
        "coef.drc"
      ]
    },
    {
      "page": "comped",
      "title": "Comparison of effective dose values",
      "topics": [
        "comped"
      ]
    },
    {
      "page": "compParm",
      "title": "Comparison of parameters",
      "topics": [
        "compParm"
      ]
    },
    {
      "page": "confint.drc",
      "title": "Confidence Intervals for model parameters",
      "topics": [
        "confint.drc"
      ]
    },
    {
      "page": "CRS.4a",
      "title": "The Cedergreen-Ritz-Streibig model",
      "topics": [
        "CRS.4a",
        "CRS.4b",
        "CRS.4c",
        "ml3a",
        "ml3b",
        "ml3c",
        "UCRS.4a",
        "UCRS.4b",
        "UCRS.4c",
        "uml3a",
        "uml3b",
        "uml3c"
      ]
    },
    {
      "page": "CRS.5a",
      "title": "Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis",
      "topics": [
        "CRS.5a",
        "CRS.5b",
        "CRS.5c",
        "ml4a",
        "ml4b",
        "ml4c",
        "UCRS.5a",
        "UCRS.5b",
        "UCRS.5c",
        "uml4a",
        "uml4b",
        "uml4c"
      ]
    },
    {
      "page": "daphnids",
      "title": "Daphnia test",
      "topics": [
        "daphnids"
      ]
    },
    {
      "page": "decontaminants",
      "title": "Performance of decontaminants used in the culturing of a micro-organism",
      "topics": [
        "decontaminants"
      ]
    },
    {
      "page": "deguelin",
      "title": "Deguelin applied to chrysanthemum aphis",
      "topics": [
        "deguelin"
      ]
    },
    {
      "page": "drm",
      "title": "Fitting dose-response models",
      "topics": [
        "drm"
      ]
    },
    {
      "page": "drmc",
      "title": "Sets control arguments",
      "topics": [
        "drmc"
      ]
    },
    {
      "page": "earthworms",
      "title": "Earthworm toxicity test",
      "topics": [
        "earthworms"
      ]
    },
    {
      "page": "ED.drc",
      "title": "Estimating effective doses",
      "topics": [
        "ED",
        "ED.drc"
      ]
    },
    {
      "page": "EDcomp",
      "title": "Comparison of relative potencies between dose-response curves",
      "topics": [
        "EDcomp",
        "relpot"
      ]
    },
    {
      "page": "etmotc",
      "title": "Effect of erythromycin on mixed sewage microorganisms",
      "topics": [
        "etmotc"
      ]
    },
    {
      "page": "EXD",
      "title": "Exponential decay model",
      "topics": [
        "EXD.2",
        "EXD.3"
      ]
    },
    {
      "page": "finney71",
      "title": "Example from Finney (1971)",
      "topics": [
        "finney71"
      ]
    },
    {
      "page": "fitted.drc",
      "title": "Extract fitted values from model",
      "topics": [
        "fitted.drc"
      ]
    },
    {
      "page": "fplogistic",
      "title": "Fractional polynomial-logistic dose-response models",
      "topics": [
        "FPL.4",
        "fplogistic"
      ]
    },
    {
      "page": "G.aparine",
      "title": "Herbicide applied to Galium aparine",
      "topics": [
        "G.aparine"
      ]
    },
    {
      "page": "gammadr",
      "title": "Gamma dose-response model",
      "topics": [
        "gammadr"
      ]
    },
    {
      "page": "gaussian",
      "title": "Normal and log-normal biphasic dose-response models",
      "topics": [
        "gaussian",
        "lgaussian"
      ]
    },
    {
      "page": "germination",
      "title": "Germination of three crops",
      "topics": [
        "germination"
      ]
    },
    {
      "page": "getInitial",
      "title": "Showing starting values used",
      "topics": [
        "getInitial"
      ]
    },
    {
      "page": "getMeanFunctions",
      "title": "Display available dose-response models",
      "topics": [
        "getMeanFunctions"
      ]
    },
    {
      "page": "glymet",
      "title": "Glyphosate and metsulfuron-methyl tested on algae.",
      "topics": [
        "glymet"
      ]
    },
    {
      "page": "gompertz",
      "title": "Mean function for the Gompertz dose-response or growth curve",
      "concept": [
        "Gompertz"
      ],
      "topics": [
        "G.2",
        "G.3",
        "G.3u",
        "G.4",
        "gompertz"
      ]
    },
    {
      "page": "gompertzd",
      "title": "The derivative of the Gompertz function",
      "topics": [
        "gompertzd"
      ]
    },
    {
      "page": "H.virescens",
      "title": "Mortality of tobacco budworms",
      "topics": [
        "H.virescens"
      ]
    },
    {
      "page": "hatvalues.drc",
      "title": "Model diagnostics for nonlinear dose-response models",
      "topics": [
        "cooks.distance.drc",
        "hatvalues.drc"
      ]
    },
    {
      "page": "heartrate",
      "title": "Heart rate baroreflexes for rabbits",
      "topics": [
        "heartrate"
      ]
    },
    {
      "page": "isobole",
      "title": "Creating isobolograms",
      "topics": [
        "isobole"
      ]
    },
    {
      "page": "barley",
      "title": "Leaf length of barley",
      "topics": [
        "leaflength"
      ]
    },
    {
      "page": "lepidium",
      "title": "Dose-response profile of degradation of agrochemical using lepidium",
      "topics": [
        "lepidium"
      ]
    },
    {
      "page": "lettuce",
      "title": "Hormesis in lettuce plants",
      "topics": [
        "lettuce"
      ]
    },
    {
      "page": "lin.test",
      "title": "Lack-of-fit test for the mean structure based on cumulated residuals",
      "topics": [
        "lin.test"
      ]
    },
    {
      "page": "LL.2",
      "title": "The two-parameter log-logistic function",
      "concept": [
        "Hill logit 2-parameter two-parameter"
      ],
      "topics": [
        "l2",
        "LL.2",
        "LL2.2"
      ]
    },
    {
      "page": "LL.3",
      "title": "The three-parameter log-logistic function",
      "concept": [
        "Hill 3-parameter three-parameter"
      ],
      "topics": [
        "l3",
        "l3u",
        "LL.3",
        "LL.3u",
        "LL2.3",
        "LL2.3u"
      ]
    },
    {
      "page": "LL.4",
      "title": "The four-parameter log-logistic function",
      "concept": [
        "Hill 4-parameter four-parameter"
      ],
      "topics": [
        "l4",
        "LL.4",
        "LL2.4"
      ]
    },
    {
      "page": "LL.5",
      "title": "The five-parameter log-logistic function",
      "concept": [
        "Hill 5-parameter five-parameter"
      ],
      "topics": [
        "l5",
        "LL.5",
        "LL2.5"
      ]
    },
    {
      "page": "llogistic",
      "title": "The log-logistic function",
      "concept": [
        "Hill"
      ],
      "topics": [
        "llogistic",
        "llogistic2"
      ]
    },
    {
      "page": "lnormal",
      "title": "Log-normal dose-response model",
      "concept": [
        "log-normal probit"
      ],
      "topics": [
        "LN.2",
        "LN.3",
        "LN.3u",
        "LN.4",
        "lnormal"
      ]
    },
    {
      "page": "logistic",
      "title": "The logistic model",
      "topics": [
        "L.3",
        "L.4",
        "L.5",
        "logistic"
      ]
    },
    {
      "page": "logLik.drc",
      "title": "Extracting the log likelihood",
      "topics": [
        "logLik.drc"
      ]
    },
    {
      "page": "M.bahia",
      "title": "Effect of an effluent on the growth of mysid shrimp",
      "topics": [
        "M.bahia"
      ]
    },
    {
      "page": "maED",
      "title": "Estimation of ED values using model-averaging",
      "topics": [
        "maED"
      ]
    },
    {
      "page": "MAX",
      "title": "Maximum mean response",
      "topics": [
        "MAX"
      ]
    },
    {
      "page": "mecter",
      "title": "Mechlorprop and terbythylazine tested on Lemna minor",
      "topics": [
        "mecter"
      ]
    },
    {
      "page": "metals",
      "title": "Data from heavy metal mixture experiments",
      "topics": [
        "metals"
      ]
    },
    {
      "page": "methionine",
      "title": "Weight gain for different methionine sources",
      "topics": [
        "methionine"
      ]
    },
    {
      "page": "mixture",
      "title": "Fitting binary mixture models",
      "topics": [
        "mixture"
      ]
    },
    {
      "page": "MM",
      "title": "Michaelis-Menten model",
      "topics": [
        "MM.2",
        "MM.3"
      ]
    },
    {
      "page": "modelFit",
      "title": "Assessing the model fit",
      "topics": [
        "modelFit"
      ]
    },
    {
      "page": "mr.test",
      "title": "Mizon-Richard test for dose-response models",
      "topics": [
        "mr.test"
      ]
    },
    {
      "page": "mselect",
      "title": "Dose-response model selection",
      "topics": [
        "mselect"
      ]
    },
    {
      "page": "multi2",
      "title": "Multistage dose-response model with quadratic terms",
      "topics": [
        "multi2"
      ]
    },
    {
      "page": "nasturtium",
      "title": "Dose-response profile of degradation of agrochemical using nasturtium",
      "topics": [
        "nasturtium"
      ]
    },
    {
      "page": "NEC",
      "title": "Dose-response model for estimation of no effect concentration (NEC).",
      "topics": [
        "NEC",
        "NEC.2",
        "NEC.3",
        "NEC.4"
      ]
    },
    {
      "page": "neill.test",
      "title": "Neill's lack-of-fit test for dose-response models",
      "topics": [
        "neill.test"
      ]
    },
    {
      "page": "noEffect",
      "title": "Testing if there is a dose effect at all",
      "topics": [
        "noEffect"
      ]
    },
    {
      "page": "O.mykiss",
      "title": "Test data from a 21 day fish test",
      "topics": [
        "O.mykiss"
      ]
    },
    {
      "page": "P.promelas",
      "title": "Effect of sodium pentachlorophenate on growth of fathead minnow",
      "topics": [
        "P.promelas"
      ]
    },
    {
      "page": "plot.drc",
      "title": "Plotting fitted dose-response curves",
      "topics": [
        "plot.drc"
      ]
    },
    {
      "page": "PR",
      "title": "Expected or predicted response",
      "topics": [
        "PR"
      ]
    },
    {
      "page": "predict.drc",
      "title": "Prediction",
      "concept": [
        "prediction"
      ],
      "topics": [
        "predict.drc",
        "predict.mrdrc"
      ]
    },
    {
      "page": "print.drc",
      "title": "Printing key features",
      "topics": [
        "print.drc"
      ]
    },
    {
      "page": "print.summary.drc",
      "title": "Printing summary of non-linear model fits",
      "topics": [
        "print.summary.drc"
      ]
    },
    {
      "page": "rdrm",
      "title": "Simulating a dose-response curve",
      "topics": [
        "rdrm"
      ]
    },
    {
      "page": "residuals.drc",
      "title": "Extracting residuals from the fitted dose-response model",
      "topics": [
        "residuals.drc"
      ]
    },
    {
      "page": "RScompetition",
      "title": "Competition between two biotypes",
      "topics": [
        "RScompetition"
      ]
    },
    {
      "page": "ryegrass",
      "title": "Effect of ferulic acid on growth of ryegrass",
      "topics": [
        "ryegrass"
      ]
    },
    {
      "page": "S.alba",
      "title": "Potency of two herbicides",
      "topics": [
        "S.alba"
      ]
    },
    {
      "page": "S.capricornutum",
      "title": "Effect of cadmium on growth of green alga",
      "topics": [
        "S.capricornutum"
      ]
    },
    {
      "page": "searchdrc",
      "title": "Searching through a range of initial parameter values to obtain convergence",
      "topics": [
        "searchdrc"
      ]
    },
    {
      "page": "secalonic",
      "title": "Root length measurements",
      "topics": [
        "secalonic"
      ]
    },
    {
      "page": "selenium",
      "title": "Data from toxicology experiments with selenium",
      "topics": [
        "selenium"
      ]
    },
    {
      "page": "simDR",
      "title": "Simulating ED values under various scenarios",
      "topics": [
        "simDR"
      ]
    },
    {
      "page": "spinach",
      "title": "Inhibition of photosynthesis",
      "topics": [
        "spinach"
      ]
    },
    {
      "page": "summary.drc",
      "title": "Summarising non-linear model fits",
      "topics": [
        "summary.drc"
      ]
    },
    {
      "page": "terbuthylazin",
      "title": "The effect of terbuthylazin on growth rate",
      "topics": [
        "terbuthylazin"
      ]
    },
    {
      "page": "twophase",
      "title": "Two-phase dose-response model",
      "topics": [
        "twophase"
      ]
    },
    {
      "page": "update.drc",
      "title": "Updating and re-fitting a model",
      "topics": [
        "update.drc"
      ]
    },
    {
      "page": "ursa",
      "title": "Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction",
      "topics": [
        "actimL",
        "genBliss",
        "genBliss2",
        "genLoewe",
        "genLoewe2",
        "genursa",
        "iceLoewe.1",
        "iceLoewe2.1",
        "ursa"
      ]
    },
    {
      "page": "vcov.drc",
      "title": "Calculating variance-covariance matrix for objects of class 'drc'",
      "topics": [
        "vcov.drc"
      ]
    },
    {
      "page": "vinclozolin",
      "title": "Vinclozolin from AR in vitro assay",
      "topics": [
        "vinclozolin"
      ]
    },
    {
      "page": "W2",
      "title": "The two-parameter Weibull functions",
      "topics": [
        "W1.2",
        "w2",
        "W2.2"
      ]
    },
    {
      "page": "W3",
      "title": "The three-parameter Weibull functions",
      "topics": [
        "W1.3",
        "W1.3u",
        "W2.3",
        "W2.3u",
        "W2x.3",
        "w3"
      ]
    },
    {
      "page": "W4",
      "title": "The four-parameter Weibull functions",
      "topics": [
        "W1.4",
        "W2.4",
        "W2x.4",
        "w4"
      ]
    },
    {
      "page": "weibull1",
      "title": "Weibull model functions",
      "topics": [
        "weibull1",
        "weibull2",
        "weibull2x"
      ]
    },
    {
      "page": "yieldLoss",
      "title": "Calculating yield loss parameters",
      "concept": [
        "rectangular hyperbola model"
      ],
      "topics": [
        "yieldLoss"
      ]
    }
  ],
  "_rundeps": [
    "abind",
    "backports",
    "boot",
    "broom",
    "car",
    "carData",
    "cli",
    "codetools",
    "colorspace",
    "cowplot",
    "cpp11",
    "Deriv",
    "doBy",
    "dplyr",
    "farver",
    "forecast",
    "Formula",
    "fracdiff",
    "generics",
    "ggplot2",
    "glue",
    "gtable",
    "gtools",
    "isoband",
    "labeling",
    "lattice",
    "lifecycle",
    "lme4",
    "lmtest",
    "magrittr",
    "MASS",
    "Matrix",
    "MatrixModels",
    "mgcv",
    "microbenchmark",
    "minqa",
    "modelr",
    "multcomp",
    "mvtnorm",
    "nlme",
    "nloptr",
    "nnet",
    "numDeriv",
    "pbkrtest",
    "pillar",
    "pkgconfig",
    "plotrix",
    "purrr",
    "quantreg",
    "R6",
    "rbibutils",
    "RColorBrewer",
    "Rcpp",
    "RcppArmadillo",
    "RcppEigen",
    "Rdpack",
    "reformulas",
    "rlang",
    "S7",
    "sandwich",
    "scales",
    "SparseM",
    "stringi",
    "stringr",
    "survival",
    "TH.data",
    "tibble",
    "tidyr",
    "tidyselect",
    "timeDate",
    "urca",
    "utf8",
    "vctrs",
    "viridisLite",
    "withr",
    "zoo"
  ],
  "_score": 8.944974917765979,
  "_indexed": true,
  "_nocasepkg": "drc",
  "_universes": [
    "cran"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "3.0-1",
      "date": "2026-06-02T07:25:07.000Z",
      "distro": "noble",
      "commit": "ad2974183da72a4978467f77615d3d41eb4026a5",
      "fileid": "af2ad57672d9c7da7b3558013457ebaee9d0cb88200ca654e33d815136c5b448",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/cran/actions/runs/26804601575"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "3.0-1",
      "date": "2026-06-02T07:25:27.000Z",
      "distro": "noble",
      "commit": "ad2974183da72a4978467f77615d3d41eb4026a5",
      "fileid": "aefe94fdb09858ec6104e43137e6809d0dc562c97821bff04e68757296b78de2",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/cran/actions/runs/26804601575"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "3.0-1",
      "date": "2026-06-02T07:25:23.000Z",
      "commit": "ad2974183da72a4978467f77615d3d41eb4026a5",
      "fileid": "2b7c073d0e7f9916f28af6e55ad487064ca623cb8d6adc60396fdc1705f57cb8",
      "status": "success",
      "buildurl": "https://github.com/r-universe/cran/actions/runs/26804601575"
    }
  ]
}