{ "_id": "6ab771c799f7aa8c6aa30acd", "Package": "digiNORM", "Type": "Package", "Title": "Data-Driven Digital PCR Normalization", "Version": "0.1.0", "Authors@R": "person(\ngiven=\"Grant C.\",\nfamily=\"O'Connell\",\nrole = c(\"aut\", \"cre\"),\nemail=\"goconnell.phd@gmail.com\",\ncomment=c(ORCID = \"0000-0002-2642-6670\"))", "Description": "Adopts the general least squares-based data-driven\nnormalization strategy developed by Heckmann et al. (2011)\n to correct for technical\nvariance in gene expression data generated via digital\npolymerase chain reaction (dPCR). Performs normalization of raw\ncopy numbers and also calculates relative variability metrics\nthat can be used to assess the impact of normalization on\nvariance.", "License": "GPL-3", "Encoding": "UTF-8", "LazyData": "true", "RoxygenNote": "7.3.3", "Author": "Grant C. O'Connell [aut, cre] (ORCID:\n)", "Maintainer": "Grant C. O'Connell ", "Config/testthat/edition": "3", "NeedsCompilation": "no", "Packaged": { "Date": "2026-09-26 07:15:11 UTC", "User": "root" }, "Repository": "https://cran.r-universe.dev", "Date/Publication": "2026-04-16 21:07:01 UTC", "RemoteUrl": "https://github.com/cran/digiNORM", "RemoteRef": "HEAD", "RemoteSha": "1a6e3ef34d52ffd28a19c15e5a4680890486e56f", "_user": "cran", "_type": "src", "_file": "digiNORM_0.1.0.tar.gz", "_fileid": "https://r2.ropensci.org/0b78ae64af0aa7fb332b201244ce37ebf7bbec6b563585c4e430c62d9fc54d65", "_filesize": 144514, "_sha256": "0b78ae64af0aa7fb332b201244ce37ebf7bbec6b563585c4e430c62d9fc54d65", "_expires": "2027-01-04T07:18:30.000Z", "_created": "2026-09-26T07:15:11.000Z", "_published": "2026-09-26T07:18:31.767Z", "_jobs": [ { "job": 108360692462, "time": 114, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "10900512927" }, { "job": 108360692405, "time": 161, "config": "linux-release-x86_64", "r": "4.6.1", "check": "OK", "artifact": "10900793217" }, { "job": 108360261805, "time": 174, "config": "source", "r": "4.6.1", "check": "OK", "artifact": "10900203341" }, { "job": 108360692411, "time": 89, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "10901315817" }, { "job": 108360692413, "time": 60, "config": "windows-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "10900393121" }, { "job": 108360692401, "time": 91, "config": "windows-release-x86_64", "r": "4.6.1", "check": "OK", "artifact": "10900673620" } ], "_host": "GitHub-Actions", "_buildurl": "https://github.com/r-universe/cran/actions/runs/36226058860", "_status": "success", "_upstream": "https://github.com/cran/digiNORM", "_commit": { "id": "1a6e3ef34d52ffd28a19c15e5a4680890486e56f", "author": "Grant C. O'\"'\"'Connell ", "committer": "cran-robot ", "message": "version 0.1.0\n", "time": 1776373621 }, "_maintainer": { "name": "Grant C. OConnell", "email": "goconnell.phd@gmail.com", "orcid": "0000-0002-2642-6670" }, "_distro": "resolute", "_registered": true, "_dependencies": [ { "package": "R", "version": ">= 3.5", "role": "Depends" }, { "package": "utils", "role": "Imports" }, { "package": "testthat", "version": ">= 3.0.0", "role": "Suggests" } ], "_owner": "cran", "_selfowned": false, "_usedby": 0, "_updates": [ { "week": "2026-16", "n": 1 } ], "_tags": [ { "name": "0.1.0", "date": "2026-04-16" } ], "_stars": 0, "_userbio": { "uuid": 6899542, "type": "organization", "name": "cran", "followers": 630, "description": "Unofficial read-only mirror of all CRAN R packages" }, "_downloads": { "count": 303, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/digiNORM" }, "_searchresults": 0, "_rbuild": "4.6.1", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/digiNORM.html", "extra/manual.pdf" ], "_realowner": "cran", "_cranurl": false, "_releases": [ { "version": "0.1.0", "date": "2026-04-16" } ], "_exports": [ "correction_factors", "digi_norm", "normalization_weights", "relative_variability" ], "_datasets": [ { "name": "multi_cond_data", "title": "Example dataset from a multi-condition dPCR experiment.", "object": "multi_cond_data", "class": [ "data.frame" ], "fields": [ "Sample_id", "Brain_region", "B2m", "Cend1", "Elavl3", "Gabra1", "Grin1", "Kif5a", "Mapt", "Mt3", "Sncb", "Stmn2" ], "rows": 64, "table": true, "tojson": true }, { "name": "single_cond_data", "title": "Example dataset from a single condition dPCR experiment.", "object": "single_cond_data", "class": [ "data.frame" ], "fields": [ "Sample_id", "Cend1", "Kif5a", "Mapt", "Mbp", "Mt3", "Plp1", "Psd2", "Stmn2", "Uchl1", "Nefl", "Mobp", "Bcan", "Elavl3", "Gfap", "Grin1" ], "rows": 10, "table": true, "tojson": true } ], "_help": [ { "page": "digiNORM-package", "title": "Data-Driven Digital PCR Normalization", "topics": [ "digiNORM-package" ] }, { "page": "correction_factors", "title": "Retrieve correction factors from digiNORM output", "topics": [ "correction_factors" ] }, { "page": "digi_norm", "title": "Normalize copy numbers using digiNORM", "topics": [ "digi_norm" ] }, { "page": "multi_cond_data", "title": "Example dataset from a multi-condition dPCR experiment.", "topics": [ "multi_cond_data" ] }, { "page": "normalization_weights", "title": "Retrieve target weights from digiNORM output", "topics": [ "normalization_weights" ] }, { "page": "relative_variability", "title": "Retrieve relative variability metrics from digiNORM output", "topics": [ "relative_variability" ] }, { "page": "single_cond_data", "title": "Example dataset from a single condition dPCR experiment.", "topics": [ "single_cond_data" ] }, { "page": "summary.digi_norm", "title": "Summarize digiNORM normalization", "topics": [ "summary.digi_norm" ] } ], "_rundeps": [], "_score": 1, "_indexed": true, "_nocasepkg": "diginorm", "_universes": [ "cran" ], "_binaries": [ { "r": "4.7.0", "os": "linux", "version": "0.1.0", "date": "2026-09-26T07:17:13.000Z", "distro": "resolute", "commit": "1a6e3ef34d52ffd28a19c15e5a4680890486e56f", "fileid": "https://r2.ropensci.org/13f4f4297d670b33b75b584167805b2d55afb3819cbace9f9cc012e2981ead55", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/cran/actions/runs/36226058860" }, { "r": "4.6.1", "os": "linux", "version": "0.1.0", "date": "2026-09-26T07:17:58.000Z", "distro": "resolute", "commit": "1a6e3ef34d52ffd28a19c15e5a4680890486e56f", "fileid": "https://r2.ropensci.org/5f027d4cfa6614b2e5eb243deb0cc39ec0c922a3101b2dc6c19d5b53aed91434", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/cran/actions/runs/36226058860" }, { "r": "4.6.0", "os": "wasm", "version": "0.1.0", "date": "2026-09-26T07:16:58.000Z", "commit": "1a6e3ef34d52ffd28a19c15e5a4680890486e56f", "fileid": "https://r2.ropensci.org/276340c502c5f1b5b50dd437c072ade51acded4bcb0d7ce2a9d89f7314608ceb", "status": "success", "buildurl": "https://github.com/r-universe/cran/actions/runs/36226058860" }, { "r": "4.7.0", "os": "win", "version": "0.1.0", "date": "2026-09-26T07:16:14.000Z", "commit": "1a6e3ef34d52ffd28a19c15e5a4680890486e56f", "fileid": "https://r2.ropensci.org/eb7c5fca8d171d15cfc92624f329f3e3af911dca704aae65d059801d2d50d222", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/cran/actions/runs/36226058860" }, { "r": "4.6.1", "os": "win", "version": "0.1.0", "date": "2026-09-26T07:16:46.000Z", "commit": "1a6e3ef34d52ffd28a19c15e5a4680890486e56f", "fileid": "https://r2.ropensci.org/cbad88bbd55853e8a395a17504206e186dfbd654ebc2e245ec213314475dcd8d", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/cran/actions/runs/36226058860" } ] }