{ "_id": "6ae3c3373d0f299392dd1e77", "Package": "cepip", "Type": "Package", "Title": "Cell Explanatory Power with Inflection Point (CEP-IP) with CMRF", "Version": "0.1.0", "Authors@R": "person(\"Kah Keng\", \"Wong\", role = c(\"aut\", \"cre\"),\nemail = \"kahkeng3@gmail.com\",\ncomment = c(ORCID = \"0000-0001-7359-6202\"))", "Description": "Implements the cell explanatory power with inflection\npoint (CEP-IP) framework for single-cell co-expression\nanalysis. A generalized additive model (GAM) fitted by\nrestricted maximum likelihood (REML) with a penalized residual\nsum of squares (PRSS) search over the basis dimension relates a\ngene of interest to the mean of its partner genes. Cells are\nranked by their explanatory power, and the inflection point is\nthe first negative-to-positive zero crossing of a residual GAM.\nOptional extensions are the Spearman-Kendall cell-level score\n(SKCS) and the copula monotone recovery filter (CMRF), which\nrecovers cells near the module through a tolerance band and a\nrepeated stratified k-fold cross-validation gate. Downstream\nhelpers give per-donor module fractions, paired donor-level\ndifferential expression and donor-level association models.\nCEP-IP is described in Wong (2026)\n.", "License": "MIT + file LICENSE", "Encoding": "UTF-8", "LazyData": "true", "VignetteBuilder": "knitr", "Config/testthat/edition": "3", "RoxygenNote": "7.3.1", "URL": "https://github.com/kahkengwong/cepip", "BugReports": "https://github.com/kahkengwong/cepip/issues", "NeedsCompilation": "no", "Packaged": { "Date": "2026-10-29 22:01:47 UTC", "User": "root" }, "Author": "Kah Keng Wong [aut, cre] (ORCID:\n)", "Maintainer": "Kah Keng Wong ", "Repository": "https://cran.r-universe.dev", "Date/Publication": "2026-10-29 21:14:50 UTC", "RemoteUrl": "https://github.com/cran/cepip", "RemoteRef": "HEAD", "RemoteSha": "49283c8c1341a9b015bfe35820d2b1f69fa87f03", "_user": "cran", "_type": "src", "_file": "cepip_0.1.0.tar.gz", "_fileid": "https://r2.ropensci.org/d69c64d13175f3184e48ba76f7d9f3f80fea74a8ba31fb7665685ac5ab0bbca9", 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