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The statistical model\nmakes maximal use of these high-throughput datasets by sharing\ninformation across transcripts to significantly improve\nuncertainty quantification and increase statistical power.\n'bakR' includes a maximally efficient implementation of this\nmodel for conservative initial investigations of datasets.\n'bakR' also provides more highly powered implementations using\nthe probabilistic programming language 'Stan' to sample from\nthe full posterior distribution. 'bakR' performs multiple-test\nadjusted statistical inference with the output of these model\nimplementations to help biologists separate signal from\nbackground. 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