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Currently, the package provides\nprocedures based on parallel replicate design and balanced\ndata, according to the U.S. Food and Drug Administration's\n\"Draft Guidance on Acyclovir\"\n.\nPotvin et al. (2008) provides the basis\nfor our adaptive design (see Method B). For a comprehensive\noverview of the method, refer to Lim et al. (2023)\n. 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