{ "_id": "6a101d5aacfb0bcc41c8a193", "Package": "TRD", "Type": "Package", "Title": "Transmission Ratio Distortion", "Version": "1.1", "Date": "2015-11-10", "Author": "Lam Opal Huang", "Maintainer": "Lam Opal Huang ", "Description": "Transmission Ratio Distortion (TRD) is a genetic\nphenomenon where the two alleles from either parent are not\ntransmitted to the offspring at the expected 1:1 ratio under\nMendelian inheritance, leading to spurious signals in genetic\nassociation studies. Functions in this package are developed to\naccount for this phenomenon using loglinear model and\nTransmission Disequilibrium Test (TDT). Some population\ninformation can also be calculated.", "License": "GPL (>= 2)", "NeedsCompilation": "no", "Packaged": { "Date": "2026-05-14 07:55:29 UTC", "User": "root" }, "Repository": "https://cran.r-universe.dev", "Date/Publication": "2015-11-11 00:41:56 UTC", "RemoteUrl": "https://github.com/cran/TRD", "RemoteRef": "HEAD", "RemoteSha": "c3ddebb3af5eeff49bbe91e3dd3c606668ab4b9c", "MD5sum": "71520af26acf4335649763686a9684aa", "_user": "cran", "_type": "src", "_file": "TRD_1.1.tar.gz", "_fileid": "ff89893da20aa6c84f5149373f0280d6ed3955c7ab53936ead1cef2487474038", "_filesize": 121794, "_sha256": "ff89893da20aa6c84f5149373f0280d6ed3955c7ab53936ead1cef2487474038", "_created": "2026-05-14T07:55:29.000Z", "_published": "2026-05-22T09:09:46.059Z", "_distro": "noble", "_jobs": [ { "job": 77349957267, "time": 105, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "ERROR", "artifact": "6989838053" }, { "job": 77349957306, "time": 108, "config": "linux-release-x86_64", "r": "4.6.0", 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"Unofficial read-only mirror of all CRAN R packages" }, "_downloads": { "count": 156, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/TRD" }, "_mentions": 1, "_searchresults": 8, "_rbuild": "4.6.0", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/TRD.html", "manual.pdf" ], "_realowner": "cran", "_cranurl": false, "_releases": [ { "version": "1.0", "date": "2015-01-21" }, { "version": "1.1", "date": "2015-11-11" } ], "_exports": [ "find.maf", "find.t", "gcount", "ll", "prev", "rtrios", "strata.cnt", "tdt" ], "_help": [ { "page": "TRD-package", "title": "Transmission Ratio Distortion", "topics": [ "TRD-package", "TRD" ] }, { "page": "find.maf", "title": "Find minor allele frequency (MAF) in case-trios, control-trios, or the whole sample.", "topics": [ "find.maf" ] }, { "page": "find.t", "title": "Find transmission ratio of minor alleles in mother, father or both parents.", "topics": [ "find.t" ] }, { "page": "findr", "title": "Find transmission ratio of minor alleles.", "topics": [ "findr" ] }, { "page": "gcount", "title": "Calculate genotype counts (additive model) for selected population.", "topics": [ "gcount" ] }, { "page": "ll", "title": "Fit Loglinear model with and without adjustment for TRD.", "topics": [ "ll" ] }, { "page": "prev", "title": "Calculate theoretical prevalence of disease", "topics": [ "prev" ] }, { "page": "rtrios", "title": "Generate simulated popoulation of case- and control-trios", "topics": [ "rtrios" ] }, { "page": "strata.cnt", "title": "Count trios for each of the 15/16 strata with mother-father-child genotypes MFC", "topics": [ "strata.cnt" ] }, { "page": "tdt", "title": "Compute TDT and adjusted TDT on case- and/or control-trios", "topics": [ "tdt" ] }, { "page": "tdt.cnt", "title": "Count transmission of allele in McNemar Table", "topics": [ "tdt.cnt" ] } ], "_rundeps": [ "Rlab" ], "_score": 1, "_indexed": true, "_nocasepkg": "trd", 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